Kungani i-HEMC iyisinqumo esingcono kune-HPMC?

I-Hypromellose (HPMC) kanye ne-hydroxyethylmethylcellulose (HEMC) yizinto ezimbili eziphuma kabanzi ze-cellulose ezisetshenziswa ezimbonini zemithi, zokudla nezimonyo. Nakuba i-HPMC ne-HEMC zabelana ngokufana okuningi, ziyehluka ngezindlela ezithile, okwenza eyodwa iphakame kwenye kwezinye izinhlelo zokusebenza.

I-HEMC iyi-ether ye-cellulose eguquliwe etholwe ngokuphendula i-methyl cellulose nge-ethylene oxide ne-ethyl chloride, bese ifaka i-ethyl esikhundleni se-hydroxyl. Ngakho-ke, i-HEMC inezinga eliphezulu lokushintshwa (DS) kune-HPMC. I-DS ibhekisela enanini elimaphakathi leyunithi ngayinye ye-glucose, ethinta izici ezibonakalayo namakhemikhali ze-polymer. Ngokuvamile, i-DS ephezulu iphumela ekuncibilikeni okungcono kakhulu kuzinyibilikisi zemvelo, amanani okuncibilika ngokushesha, kanye nokuthambekela okukhulayo kokumunca amanzi. I-DS ye-HEMC ivamise ukuba ngu-1.7-2.0, kuyilapho i-DS ye-HPMC ivamise ukuba phakathi kuka-1.2 no-1.5.

Inzuzo ehlukile ye-HEMC ngaphezu kwe-HPMC umthamo wayo omuhle kakhulu wokugcina amanzi, okuyenza ilungele ukwakheka kokunamathelayo, izinto zokwakha kanye neminye imikhiqizo edinga ukugcinwa kwamanzi okuhle. I-HEMC futhi imelana kakhulu nokuhlasela kwamagciwane kune-HPMC futhi ineshelufu ende nempilo. Ukwanda kwe-hydrophobicity ye-HEMC kanye nokuba khona kwamaqembu e-ethyl emhlane wayo kwenza kube i-emulsifier enhle kakhulu futhi ingathuthukisa ukuzinza kwesikhathi eside kwama-emulsions.

Enye inzuzo yokusebenzisa i-HEMC ukuhambisana kwayo namanye amakhemikhali amaningi, okunomthelela ekusebenzisaneni kwayo nezinto ezihlukahlukene ezinhlelweni ezihlukene. Ukwengeza, i-HEMC inezinto ezinhle zokwenza ifilimu, okwenza kube usizo ekukhiqizeni ama-coatings kanye nama-binders ekukhiqizeni amaphilisi, amaphilisi nama-granules.

Ngakolunye uhlangothi, i-HPMC inezinto ezingcono zokugelisa ezishisayo, okuyenza ibe ukukhetha okuhle kakhulu kokwenziwa kwemithi ekhishwa kancane edinga amajeli azwela ukushisa. I-HPMC futhi inokuncibilika okungcono kwamanzi futhi ayithambekele kangako ekwenzeni ama-coagglomerate, okungamaqoqo angancibiliki ama-polymers esixazululweni.

Sengiphetha, kokubili i-HEMC kanye ne-HPMC kuyizinto eziphuma ku-cellulose ezibalulekile ezinikeza izinzuzo ezihlukile kuye ngohlelo lokusebenza. I-HEMC inokugcinwa kwamanzi okungcono, i-emulsification, nokuhambisana namanye amakhemikhali, kuyilapho i-HPMC inezakhiwo ezinhle kakhulu ze-thermogelling kanye nokuncibilika kwamanzi. Ngakho-ke, ukukhetha phakathi kwe-HEMC ne-HPMC kuncike esicelweni esifunwayo, inqubo yokukhiqiza kanye nezidingo zokugcina zomkhiqizo.