I-HPMC (i-hydroxypropyl methylcellulose) yinto evamise ukusetshenziswa esetshenziswa njenge-polymer encibilika emanzini engeyona ionic, esetshenziswa kabanzi kwezemithi, ekudleni, ekwakhiweni, ekunakekelweni komuntu siqu nakweminye imikhakha.
1. Izakhiwo zesakhiwo
Isakhiwo samangqamuzana e-HPMC sine-viscosity ephezulu kanye nezakhiwo ezinhle ze-rheological. Kunamaqembu amaningi e-hydroxyl (-OH) ochungechungeni lwawo lwamangqamuzana, angakha amabhondi e-hydrogen nama-molecule wamanzi, ukuze i-HPMC incibilike ngokuphumelelayo emanzini ukuze yakhe isixazululo se-colloidal high-viscosity. Lesi sakhiwo sivumela i-HPMC ukuthi iqine ngempumelelo kufomula futhi ikhulise i-viscosity yomkhiqizo.
2. Ukuqina komphumela
Umthelela wokujiya we-HPMC ufinyelelwa ngokuyinhloko ngokusebenzisana kwamaketanga ayo amangqamuzana. Lapho i-HPMC ichitheka emanzini, amaketanga amangqamuzana azohlangana ukuze enze isakhiwo senethiwekhi, ngaleyo ndlela andise i-viscosity yesisombululo. Lo mphumela wokujiya ubonakala ikakhulukazi emikhiqizweni ewuketshezi (njengeziphuzo, izinongo) kanye nemikhiqizo yokunamathisela (njengamafutha okugcoba, imikhiqizo yokunakekelwa kwesikhumba), engathuthukisa ukunambitheka nokusebenzisa isipiliyoni somkhiqizo.
3. Ukuzinza okuthuthukisiwe
Ngokwandisa i-viscosity, i-HPMC ingaphinde ithuthukise ukuzinza komkhiqizo. Kuma-suspensions amaningi kanye nama-emulsions, i-viscosity ekhulayo ingavimbela ukubola kanye nokuhlukaniswa kwesigaba sezinhlayiya eziqinile, ngaleyo ndlela kugcinwe ukufana nokubukeka komkhiqizo. Isibonelo, ekugqokeni nasekunamathiseleni, ukusetshenziswa kwe-HPMC kungathuthukisa ukuzinza kwe-rheological yomkhiqizo futhi kuvimbele ukuvela kwe-sedimentation kanye ne-stratification.
4. Ukusebenza kokukhishwa okulawulwayo
Emkhakheni wokwenza imithi, i-HPMC ivamise ukusetshenziswa njengengxenye yezinhlelo zokukhishwa ezilawulwa izidakamizwa. Ngokulungisa ukuhlushwa kanye nesisindo samangqamuzana e-HPMC, ukukhululwa okuqhubekayo nokulawulwayo kwezidakamizwa kungafinyelelwa. Izakhiwo zokuvuvukala ze-HPMC emanzini zivumela izinga lokukhululwa kwezidakamizwa emzimbeni ukuthi lilawulwe, ngaleyo ndlela kuthuthukiswe ukusebenza kahle kwezidakamizwa nokunciphisa imiphumela emibi.
5. Ukuvumelana nezimo okubanzi
I-HPMC isengagcina izakhiwo ezinhle zokujiya ezindaweni ezinamavelu e-pH ahlukene namandla e-ionic, okuyenza isebenze ekuhlanganiseni okuningi okuyinkimbinkimbi. Kungakhathaliseki ukuthi isistimu ene-acidic, alkaline noma engathathi hlangothi, i-HPMC inganikeza i-viscosity ezinzile futhi ithuthukise ukusebenza komkhiqizo.
6. Ukusebenza okuphansi kokugxila
Uma kuqhathaniswa namanye ama-thickeners, i-HPMC ingakhuphula ngempumelelo i-viscosity ezindaweni eziphansi, inciphise izindleko zokukhiqiza. Ngesikhathi esifanayo, lokhu kuhlanganiswa okuphansi kunganciphisa umthelela kwezinye izithako futhi kugcine ukuguquguquka nokuzinza kwefomula.
7. Izici ezinomthelela
Ukuqina komphumela we-HPMC kuthintwa izici eziningi, okuhlanganisa uhlobo lwe-HPMC (njengesisindo samangqamuzana ahlukene, ukufakwa esikhundleni kwe-hydroxyl), izinga lokushisa lesixazululo, ukugxiliswa kwe-ion, njll. Ezinhlelweni ezithile, kuyadingeka ukwenza izinguquko ezihambisanayo ngokuvumelana nezidingo. yomkhiqizo ukufeza umphumela omuhle kakhulu we-viscosity.
8. Izibonelo zohlelo lokusebenza
Embonini yokudla, i-HPMC ivame ukusetshenziselwa ukwenza ukudla okunamafutha aphansi nemikhiqizo yobisi ukusiza ukuthuthukisa ukunambitheka nokuvumelana. Embonini yezokwakha, i-HPMC isetshenziswa ezintweni ezisekelwe kusimende ukuthuthukisa ukunamathela nokusebenza. Emkhakheni wokwenza imithi, i-HPMC isetshenziswa kakhulu kumaphilisi, amaphilisi kanye namafomu emithamo ahlukahlukene ukuze kuthuthukiswe uketshezi nokuzinza kwawo.
Iqhaza le-HPMC ekwenzeni ngcono i-viscosity yomkhiqizo alinakubukelwa phansi. Izakhiwo zayo eziyingqayizivele zomzimba namakhemikhali ziyenza ibe ukuqina nokuqiniswa okubalulekile ezimbonini eziningi. Lapho ukhetha futhi usebenzisa i-HPMC, kuyadingeka ukwenza izilinganiso ezifanele futhi isetshenziswe ngokuya ngezimpawu nezidingo zemikhiqizo ethile ukuze unikeze ukudlala okugcwele ezinzuzweni zayo.
Isikhathi sokuthumela: Oct-21-2024