IHydroxypropylmethylcellulose (HPMC) iyinhlanganisela yamangqamuzana esebenza ngezinto eziningi esetshenziswe kabanzi embonini yezokwakha. Isetshenziswa kabanzi ezinhlelweni ze-putty njengoba ithuthukisa ukusebenza okuphelele kanye nekhwalithi ye-putty. Kulesi sihloko, sizohlola ukusetshenziswa kwe-HPMC ku-putty, sihlaziye izinkinga ezingase ziphakame ngesikhathi sokusetshenziswa kwayo, futhi sabelane ngamathiphu okuthi ungazigwema kanjani lezi zinkinga.
Okokuqala, ake sibhekisise izici ze-HPMC. I-nonionic cellulose ether, encibilika emanzini nezinye izincibilikisi zemvelo. Isakhiwo sayo samangqamuzana esiyingqayizivele siyinikeza i-viscosity enhle kakhulu, ukugcinwa kwamanzi kanye nezakhiwo zokunamathela. Ngakho-ke, iyisengezo esifanelekile sezinhlelo zokusebenza ze-putty.
I-HPMC ingasetshenziswa njenge-thickener, binder kanye ne-emulsifier ekwenziweni kwe-putty. Inokugcinwa kwamanzi okuhle kakhulu okusiza ukuvimbela i-putty ukuthi yome ngokushesha. Iphinde ithuthukise ukunamathela kwe-putty ku-substrate, iyenze ihlale isikhathi eside. Lezi zakhiwo zenza i-HPMC ibe isithako esibalulekile kuma-putty ekhwalithi ephezulu.
Kodwa-ke, ezinye izinkinga zingase zenzeke lapho i-HPMC isetshenziswa ku-putty. Inkinga yokuqala ukuthi i-HPMC iyazwela ku-pH kanye nokushintsha kwezinga lokushisa. Uma i-pH yokwakheka kwe-putty ine-asidi kakhulu, ingabangela i-HPMC ukuthi ilahlekelwe yi-viscosity. Ngesikhathi esifanayo, uma izinga lokushisa liphezulu kakhulu, lizokwenza ukuthi i-HPMC ihlehlise, okuzothinta ukusebenza kwe-putty.
Enye inkinga engase iphakame ukunqwabelana. Uma i-HPMC ingaxubene kahle nezinye izithako kwifomula ye-putty, ingase yakhe ama-clumps noma ama-clumps. Lezi zigaxa zithinta ikhwalithi ye-putty, okwenza ingabi bushelelezi futhi kube nzima ukuyifaka.
Ukuze ugweme lezi zinkinga, eminye imithetho eyisisekelo kufanele ilandelwe lapho kusetshenziswa i-HPMC ezinhlelweni ze-Putty. Okokuqala, kuyadingeka ukukhetha uhlobo olufanele lwe-HPMC lokwakhiwa kwe-putty. Izinhlobo ezihlukene ze-HPMC zingase zibe nezici ezihlukile, ngakho-ke uhlobo olulungile kufanele lukhethelwe uhlelo oluthile.
Okwesibili, kubalulekile ukuhlanganisa kahle i-HPMC nezinye izithako ekwakhiweni kwe-putty. Lokhu kuzosiza ukuvimbela izigaxa noma izigaxa. Kubalulekile futhi ukusebenzisa inqubo efanele yokuxuba ukuze uqinisekise ukuthi i-putty ixubene kahle.
Okwesithathu, qaphela i-pH nezinga lokushisa lefomula ye-putty. Kubalulekile ukuqinisekisa ukuthi i-pH ingaphakathi kwebanga elinconyiwe lohlobo oluthile lwe-HPMC esetshenziswayo. Kubalulekile futhi ukuqapha izinga lokushisa lokwakheka futhi uligcine ngaphakathi kwebanga elinconyiwe ukuze kuvinjelwe ukuwohloka kwe-HPMC.
Kafushane, i-HPMC iyisithako esibalulekile ekwenziweni kwe-putty yekhwalithi ephezulu. Inikeza ukugcinwa kwamanzi okuhle kakhulu, izici zokunamathela kanye ne-viscosity ezingathuthukisa ukusebenza okuphelele kanye nekhwalithi yama-putty. Kodwa-ke, ezinye izinkinga zingase zenzeke phakathi nokusetshenziswa kwayo, njengokuzwela ku-pH kanye noshintsho lokushisa, i-caking, njll Ngokulandela imithetho ethile eyisisekelo lapho usebenzisa i-HPMC, lezi zinkinga zingagwenywa futhi i-putty yekhwalithi ephezulu ingatholakala.
Isikhathi sokuthumela: Jul-27-2023