Ukusetshenziswa kwe-CMC kwezokwelapha

I-Carboxymethyl cellulose (CMC) iyi-polymer encibilika emanzini etholakala ku-cellulose, esetshenziswa kabanzi embonini yezokwelapha ngenxa yezakhiwo zayo ezihlukile, njengokuvumelana kwe-biocompatibility, ukungabi nobuthi, kanye nekhono elihle kakhulu lokunamathela kwe-mucoadhesive. Kulesi sihloko, sizoxoxa ngezicelo ezahlukahlukene ze-CMC kwezokwelapha.

1. Izicelo ze-Ophthalmic: I-CMC isetshenziswa kabanzi emalungiselelweni e-ophthalmic, njengamaconsi esweni namafutha okugcoba, ngenxa yekhono layo lokwandisa isikhathi sokuhlala somuthi endaweni ye-ocular, ngaleyo ndlela ithuthukise i-bioavailability yayo. I-CMC futhi isebenza njenge-ejenti yokuqina futhi inikeza ukuthambisa, ukunciphisa ukucasuka okubangelwa ukusetshenziswa komuthi.
2. Ukuphulukiswa kwesilonda: Ama-hydrogel asekelwe ku-CMC akhiwe ukuze asetshenziswe ukupholisa amanxeba. Lawa ma-hydrogel anokuqukethwe okuphezulu kwamanzi futhi ahlinzeka ngendawo emanzi ekhuthaza ukuphulukiswa kwesilonda. Ama-hydrogel e-CMC nawo ane-biocompatibility enhle kakhulu futhi angasetshenziswa njengezikafula zokukhula kwamaseli nezicubu.
3. Ukulethwa kwezidakamizwa: I-CMC isetshenziswa kakhulu ezinhlelweni zokulethwa kwezidakamizwa, njengama-microspheres, ama-nanoparticles, nama-liposomes, ngenxa yokuhambisana kwayo ne-biocompatibility, i-biodegradability, kanye nezakhiwo ze-mucoadhesive. Amasistimu okulethwa kwezidakamizwa asuselwa ku-CMC angathuthukisa ukutholakala kwezidakamizwa, ehlise ubuthi bazo, futhi anikeze ukulethwa okuhlosiwe ezicutshini ezithile noma izitho ezithile.
4. Izinhlelo zokusebenza zamathumbu: I-CMC isetshenziswa ekwakhiweni kwamaphilisi namaphilisi ukuze kuthuthukiswe izakhiwo zawo zokuhlakazeka nokuhlakazeka. I-CMC iphinde isetshenziswe njengesihlanganisi kanye nesihlukanisi ekwakhiweni kwamaphilisi ahlakaza ngomlomo. I-CMC isetshenziswa ekwakhiweni kokumiswa kanye nama-emulsions ukuze kuthuthukiswe ukuzinza kwawo kanye ne-viscosity.
5. Izinhlelo zokusebenza zamazinyo: I-CMC isetshenziswa ekwakhiweni kwamazinyo, okufana ne-toothpaste kanye ne-mouthwash, ngenxa yekhono layo lokuhlinzeka nge-viscosity kanye nokuthuthukisa izici zokugeleza kokwakheka. I-CMC futhi isebenza njengesibophezelo, ivimbela ukuhlukaniswa kwezingxenye ezihlukene zokwakheka.
6. Ukufakwa kwesitho sangasese sowesifazane: I-CMC isetshenziswa ekwakhiweni kwesitho sangasese sowesifazane, njengamajeli nokhilimu, ngenxa yezakhiwo zayo zokunamathisela i-mucoadhesive. Ukwakhiwa okusekelwe ku-CMC kungathuthukisa isikhathi sokuhlala komuthi ku-mucosa yangasese, ngaleyo ndlela kuthuthukise ukutholakala kwawo kwe-bioavailability.

Sengiphetha, i-CMC iyi-polymer eguquguqukayo enezinhlobonhlobo zezicelo kwezokwelapha. Izici zayo eziyingqayizivele, ezifana ne-biocompatibility, non-toxicity, kanye nekhono lokunamathela kwe-mucoadhesive, kuyenza ibe isithako esibalulekile ekulungiseleleni amehlo, ukuphulukiswa kwesilonda, izinhlelo zokulethwa kwezidakamizwa, ukwakheka kwamathumbu, ukwakheka kwamazinyo, kanye nokulungiswa kwesitho sangasese sowesifazane. Ukusetshenziswa kokwakheka okusekelwe ku-CMC kungathuthukisa ukutholakala kwezidakamizwa kwezidakamizwa, kunciphise ubuthi bazo, futhi kunikeze ukulethwa okuhlosiwe ezicutshini ezithile noma ezithweni ezithile, ngaleyo ndlela kuthuthukise imiphumela yesiguli.