I-Action Mechanism Yokuqiniswa Kweziphuzo Zobisi Olune-Acidified yi-CMC
Iziphuzo zobisi ezine-Acid seziye zanda kakhulu eminyakeni yamuva ngenxa yezinzuzo zazo zezempilo kanye nokunambitheka okuyingqayizivele. Kodwa-ke, lezi ziphuzo zingase zibe inselele ukuzinza, njengoba i-asidi ebisini ingabangela amaprotheni ukuthi ahlangane futhi akhe ama-aggregate, okuholela ekudambiseni nasekuhlukaneni. Enye indlela ephumelelayo yokusimamisa iziphuzo zobisi ezine-asidi iwukusebenzisa i-carboxymethyl cellulose (CMC), i-polymer encibilika emanzini engakwazi ukusebenzisana namaprotheni nezinye izithako ukwakha ukumiswa okuzinzile. Kulesi sihloko, sizoxoxa ngendlela yesenzo sokuzinzisa iziphuzo zobisi ezine-asidi yi-CMC.
Isakhiwo kanye Nezakhiwo ze-CMC
I-CMC iphuma ku-cellulose, i-polymer yemvelo etholakala ezindongeni zamaseli ezitshalo. Yenziwa ngokushintsha amakhemikhali i-cellulose ngamaqembu e-carboxymethyl, athuthukisa ukunyibilika kwayo kwamanzi nezinye izakhiwo. I-CMC iyi-polymer enamagatsha amaningi enomgogodla omude womugqa kanye namaketanga amaningi aseceleni amaqembu e-carboxymethyl. Izinga lokushintshwa (DS) le-CMC libhekisela enanini lamaqembu e-carboxymethyl ngeyunithi ngayinye ye-cellulose, futhi linquma izinga lokuncibilika kanye ne-viscosity ye-CMC.
I-Action Mechanism ye-CMC Ekuqiniseni Iziphuzo Zobisi Olune-Acidified
Ukwengezwa kwe-CMC eziphuzweni zobisi ezine-asidi kungathuthukisa ukuzinza kwazo ngezindlela ezimbalwa:
- I-Electrostatic Repulsion: Amaqembu e-carboxymethyl ku-CMC akhokhiswa kabi futhi angasebenzisana namaprotheni ashajwe kahle nezinye izithako obisini, okudala amandla anyanyekayo avimbela amaprotheni ukuthi angahlangani futhi azinze. Lokhu kwe-electrostatic repulsion kuzinza ukumiswa futhi kuvimbele ukubola.
- Ukusebenzisana kwe-Hydrophilic: Imvelo ye-hydrophilic ye-CMC iyivumela ukuthi ihlanganyele nama-molecule amanzi nezinye izakhi ze-hydrophilic obisini, zenze ungqimba oluvikelayo oluzungeze amaprotheni futhi luwavimbele ukuthi axhumane.
- Isithiyo Esiqinile: Isakhiwo esinamagatsha eI-CMCkungakha umphumela wesithiyo obulalayo, ukuvimbela amaprotheni ukuthi angasondelani futhi akhe ama-aggregate. Amaketanga amade, aguquguqukayo e-CMC nawo angagoqa izinhlayiya zamaprotheni, enze umgoqo ozivimbela ukuthi zingathintani.
- I-Viscosity: Ukwengezwa kwe-CMC eziphuzweni zobisi ezine-asidi kungakhuphula i-viscosity yazo, engavimbela ukuthungwa kwenhlabathi ngokunciphisa isivinini sokumisa izinhlayiya. I-viscosity ekhuphukile ingaphinda idale ukumiswa okuzinzile ngokuthuthukisa ukusebenzisana phakathi kwe-CMC nezinye izithako obisini.
Izinto Ezithinta Ukuqiniswa Kweziphuzo Zobisi Olune-Acidified yi-CMC
Ukusebenza kwe-CMC ekuqiniseni iziphuzo zobisi ezine-asidi kuncike ezintweni ezimbalwa, ezihlanganisa:
- I-pH: Ukuzinza kweziphuzo zobisi ezine-asidi kuthonywa kakhulu i-pH. Emazingeni aphansi e-pH, amaprotheni obisi ayashintshashintsha futhi akhe ama-aggregate kalula, okwenza ukuzinza kube inselele. I-CMC ingakwazi ukuzinzisa iziphuzo zobisi ezine-asidi ngamanani e-pH aphansi njengo-3.5, kodwa ukusebenza kwawo kwehla ngamavelu e-pH aphansi.
- Ukugxila kwe-CMC: Ukugxila kwe-CMC obisini kuthinta izici zayo zokuzinzisa. Ukugxila okuphezulu kwe-CMC kungaholela ekwandeni kwe-viscosity nokuzinza okuthuthukisiwe, kodwa ukugxila okuphezulu kakhulu kungabangela ukuthungwa nokunambitha okungafuneki.
- Ukugxila Kwamaprotheni: Ukugxila kanye nohlobo lwamaprotheni obisini kungathinta ukuzinza kwesiphuzo. I-CMC iphumelela kakhulu ekuzinziseni iziphuzo ezinamaphrotheni aphansi, kodwa futhi ingasimamisa iziphuzo ezinokuqukethwe okuphezulu kwamaprotheni uma izinhlayiya zamaprotheni zizincane futhi zisakazwa ngokulinganayo.
- Izimo Zokucubungula: Izimo zokucubungula ezisetshenziselwa ukukhiqiza isiphuzo sobisi olune-asidi zingaphazamisa ukuzinza kwaso. Amandla aphezulu we-shear kanye nokushisa kungabangela ukuguqulwa kwamaprotheni kanye nokuhlanganisa, okuholela ekungazinzini. Izimo zokucubungula kufanele zithuthukiswe ukuze kuncishiswe amaprotheni.
Isiphetho
Sengiphetha, ukuqiniswa kweziphuzo zobisi ezine-asidi yi-CMC kuyinqubo eyinkimbinkimbi ehlanganisa izindlela ezimbalwa, okuhlanganisa ukuxoshwa kwe-electrostatic, ukusebenzisana kwe-hydrophilic, isithiyo esibulalayo, kanye ne-viscosity. Lezi zindlela zisebenza ndawonye ukuze kuvinjelwe ukuhlangana kwamaprotheni kanye ne-sedimentation, okuholela ekumisweni okuzinzile nokufana okufanayo. Ukusebenza kwe-CMC ekuqiniseni iziphuzo zobisi ezine-asidi kuncike ezintweni ezimbalwa, okuhlanganisa i-pH, ukugxilisa ingqondo kwe-CMC, ukugxiliswa kwamaprotheni, nezimo zokucubungula. Ngokuqonda indlela yokusebenza ye-CMC ekuzinziseni iziphuzo zobisi ezine-asidi, abakhiqizi bangathuthukisa ukwakheka kwabo ukuze bathole ukuzinza nokuthungwa okufiselekayo kuyilapho begcina ukunambitheka nezinzuzo zezempilo zesiphuzo.
Isikhathi sokuthumela: Mar-18-2023