4 Ubuchwepheshe Bokukhiqiza Okuyisisekelo kanye Namafomula we-HPMC, Ungaphuthelwa!

IHydroxypropyl methylcellulose (HPMC) iyi-polymer eguquguqukayo esetshenziswa kabanzi ezimbonini ezahlukahlukene, kufaka phakathi izimboni zokwakha, ezemithi, nezokudla. I-HPMC ikhiqizwa kusetshenziswa ubuchwepheshe obuhlukahlukene bokukhiqiza kanye nokwakheka, kuye ngohlelo oluhlosiwe. Kulesi sihloko, sizohlola ubuchwepheshe obune obuyisisekelo bokukhiqiza namafomula we-HPMC okungafanele uwageje.

1. Ubuchwepheshe be-Etherification Ubuchwepheshe be-etherification ubuchwepheshe bokukhiqiza obusetshenziswa kakhulu be-HPMC. Kule nqubo, i-cellulose iphathwa nge-alkali, njenge-sodium hydroxide, ukwenza i-alkali cellulose. I-alkali cellulose bese isabela nge-propylene oxide kanye ne-methyl chloride ukwenza i-HPMC. I-degree of substitution (DS) ye-HPMC ingalawulwa ngokulungisa isilinganiso se-propylene oxide ku-methyl chloride ngesikhathi sokusabela.

Ifomula ye-HPMC ekhiqizwa kusetshenziswa ubuchwepheshe be-etherification ithi:

I-Cellulose + Alkali → I-Alkali Cellulose I-Alkali Cellulose + Propylene Oxide + Methyl Chloride → HPMC

2. Ubuchwepheshe Bokomisa Ngokufutha Ubuchwepheshe bokumisa isifutho bubuchwepheshe bokukhiqiza obuthuthuke kakhulu be-HPMC. Kule nqubo, i-cellulose incibilika kusisombululo se-alkali bese isabela nge-propylene oxide ne-methyl chloride. Isixazululo se-HPMC esiwumphumela sibe sesifafazwa somisiwe ukukhiqiza impushana ye-HPMC.

Ifomula ye-HPMC ekhiqizwa kusetshenziswa ubuchwepheshe bokumisa isifutho yile:

I-Cellulose + Alkali → I-Alkali Cellulose I-Alkali Cellulose + Propylene Oxide + Methyl Chloride → Isixazululo se-HPMC Isixazululo se-HPMC + Ukomisa Isifutho → I-HPMC Powder

3. I-Suspension Polymerization Technology Ubuchwepheshe be-suspension polymerization bungobunye ubuchwepheshe bokukhiqiza be-HPMC. Kule nqubo, i-cellulose imiswa ku-solvent bese isabela nge-propylene oxide ne-methyl chloride phambi kwesiqalisi se-polymerization ukuze kwakhiwe i-HPMC.

Ifomula ye-HPMC ekhiqizwa kusetshenziswa ubuchwepheshe be-polymerization yokumiswa yile:

I-Cellulose + Solvent + Polymerization Initiator → Ukumiswa KweCellulose Ukumiswa + I-Propylene Oxide + Methyl Chloride → HPMC

4. Isixazululo se-Polymerization Technology Ubuchwepheshe be-polymerization besixazululo ubuchwepheshe obusha bokukhiqiza be-HPMC. Kule nqubo, i-cellulose incibilika ku-solvent bese isabela nge-propylene oxide ne-methyl chloride phambi kwesiqalisi se-polymerization ukuze kwakhiwe i-HPMC.

Ifomula ye-HPMC ekhiqizwa kusetshenziswa ubuchwepheshe be-polymerization yesisombululo ithi:

I-Cellulose + Solvent + Polymerization Initiator → Cellulose Solution Cellulose Solution + Propylene Oxide + Methyl Chloride → HPMC

Sengiphetha, i-HPMC iyi-polymer eguquguqukayo ekhiqizwa kusetshenziswa ubuchwepheshe obuhlukahlukene bokukhiqiza kanye nokubunjwa, kuye ngokusetshenziswa okuhlosiwe. Ubuchwepheshe obune obuyisisekelo bokukhiqiza kanye namafomula e-HPMC ahlanganisa ubuchwepheshe be-etherification, ubuchwepheshe bokumisa isifutho, ubuchwepheshe bokumiswa kwe-polymerization, kanye nobuchwepheshe be-polymerization yesisombululo. Ukuqonda ubuchwepheshe bokukhiqiza kanye nefomula ye-HPMC kungasiza abakhiqizi bakhethe umkhiqizo olungile we-HPMC wezinhlelo zabo zokusebenza ezithile.