IHydroxypropylmethylcellulose (HPMC) iyi-polymer encibilika emanzini etholakala ku-cellulose yemvelo futhi isetshenziswa kabanzi ezimbonini eziningi ngenxa yekhono layo lokukhiqiza uhla lwama-viscosity ezixazululweni ezinamanzi. I-HPMC inezinhlobonhlobo zezicelo ezimbonini zemithi, zokudla nezimonyo. I-Viscosity iyisibaluli esiyinhloko sezixazululo ze-HPMC ezithinta ukusebenza kwazo kulezi zinhlelo zokusebenza.
Izinto ezithinta i-viscosity:
1. Ukugxila: Ukugxila kwe-HPMC kusixazululo kuhlobene ngokuqondile ne-viscosity yesisombululo. Njengoba ukugxila kwe-HPMC kukhuphuka, i-viscosity yesisombululo iyakhula njengoba amaketanga e-polymer ethandeka kakhulu. Kodwa-ke, ukugxila okuphezulu kakhulu kungabangela isisombululo esiqinile futhi esifana nejeli, esingase singafiseleki kwezinye izinhlelo zokusebenza.
2. Isisindo samangqamuzana: Isisindo samangqamuzana e-HPMC siyisici esiyinhloko esithinta i-viscosity yesisombululo. Njengoba isisindo samangqamuzana e-HPMC sikhula, i-viscosity yesisombululo nayo iyanda ngenxa yokwanda kokubopha kwamaketanga e-polymer. I-HPMC enesisindo se-molecular ephakeme inamaketanga amade, okuholela esixazululweni se-viscous ngaphezulu.
3. Izinga lokushisa: I-viscosity yesisombululo se-HPMC nayo ithintwa izinga lokushisa. Njengoba izinga lokushisa lesisombululo landa, i-viscosity yesisombululo iyancipha. Ukuncipha kwe-viscosity kungenxa yokuncipha kwamandla e-intermolecular phakathi kwamaketanga e-polymer, okuholela ekubambeni okuncane kanye nokwanda kwe-fluidity.
4. Inani le-pH: Inani le-pH lesixazululo lizophinde lithinte i-viscosity yesisombululo se-HPMC. Amanani e-pH angaphandle kobubanzi obungu-5.5-8 angabangela ukwehla kwe-viscosity ngenxa yezinguquko ekuncibilikeni kanye nokushajwa kwepolymer ye-HPMC.
5. Usawoti: Usawoti noma amandla e-ionic esixazululo nawo athinta i-viscosity yesisombululo se-HPMC. Ukwanda kokuhlushwa kukasawoti kuphazamisa ukusebenzisana kwe-HPMC polymer chain, okuholela ekwehleni kwe-viscosity yesisombululo.
6. Izimo zokugunda: Izimo zokugunda lapho isixazululo se-HPMC sivezwa khona zizophinde zithinte i-viscosity yesisombululo. Izimo ze-shear zingabangela ukwehla kwesikhashana kwe-viscosity, njengalapho kuxutshwa noma ukupompa isixazululo. Uma isimo se-shear sisusiwe, i-viscosity ibuyela ngokushesha esimweni sokuzinza.
Ekuphetheni:
I-viscosity yezixazululo ezinamanzi ze-HPMC ithintwa izinto ezihlukahlukene ezidinga ukucatshangelwa lapho kwakhiwa umkhiqizo. Ukugxila, isisindo samangqamuzana, izinga lokushisa, i-pH, usawoti, nezimo zokugunda yizinto ezibaluleke kakhulu ezithinta i-viscosity yezixazululo ze-HPMC. Ukuqonda lezi zici kungasiza abakhiqizi bandise i-viscosity yezixazululo ze-HPMC zezinhlelo zokusebenza ezithile. I-Viscosity iyisici esibalulekile sezixazululo ze-HPMC njengoba inganquma ukusebenza nokuzinza kwemikhiqizo esekelwe ku-HPMC.
Isikhathi sokuthumela: Oct-16-2023