IHydroxypropylmethylcellulose (HPMC) ingenye yezinto ezisetshenziswa kakhulu embonini yezemithi nokudla kanye nasembonini yezokwakha. Enye yezinzuzo eziyinhloko ze-HPMC yikhono layo lokugcina amanzi, okuyenza ilungele izinhlelo zokusebenza ezihlukahlukene. Ukusebenza kokugcinwa kwamanzi kwe-HPMC kuthintwa izici eziningi, okuhlanganisa i-viscosity, okuqukethwe, izinga lokushisa elizungezile kanye nesakhiwo samangqamuzana.
i-viscosity
Enye yezinto eziyinhloko ezithinta ukusebenza kokugcinwa kwamanzi kwe-HPMC yi-viscosity yayo. I-viscosity isho ukujiya noma ukumelana nokugeleza kwento. Ku-HPMC, ukuphakama kwe-viscosity, kuyanda ukugcinwa kwamanzi.
I-viscosity ephakeme i-HPMC inesisindo se-molecular ephakeme, okusho ukuthi amaketanga e-polymer amade. Amaketanga amade enza kube nzima ukuthi ama-molecule amanzi ahambe phakathi kwezinto. Lokhu kubangela ukugcinwa kwamanzi okuphezulu njengoba ama-molecule amanzi evaleleke ngaphakathi kwe-polymer matrix, okuthuthukisa amandla onke e-matrix.
okuqukethwe
Esinye isici esithinta ukusebenza kokugcinwa kwamanzi kwe-HPMC okuqukethwe. I-HPMC iqukethe izingxenye ezimbili eziyinhloko ezinamazinga ahlukene e-hydrophilicity, okuyi-methoxyl ne-hydroxypropyl. Ukuphakama kokuqukethwe kwe-hydroxypropyl ku-HPMC, kuba mkhulu umthamo wokugcina amanzi.
Iqembu le-hydroxypropyl ku-HPMC linquma ukusebenza kwalo kokugcinwa kwamanzi. Lawa maqembu aheha futhi agcine ama-molecule amanzi, okwenza i-HPMC ivuvuke. Lokhu kuvuvukala kusiza ukwakha umgoqo obambezela ukuphuma kwamanzi ku-HPMC. Amaqembu e-Methoxy, ngakolunye uhlangothi, awawona ama-hydrophilic njengamaqembu e-hydroxypropyl futhi ngaleyo ndlela awafaki isandla ngokuphawulekayo kumthamo wokugcina amanzi.
izinga lokushisa elizungezile
Izinga lokushisa le-ambient ngenye into ethinta ukusebenza kokugcinwa kwamanzi kwe-HPMC. Njengoba izinga lokushisa likhuphuka, amandla okugcina amanzi e-HPMC ayehla. Lokhu kwenzeka ngoba emazingeni okushisa aphezulu, amaketanga e-polymer e-HPMC anamandla e-kinetic engeziwe, futhi ahamba ngokushesha. Ngenxa yalokho, ama-molecule amanzi akhululwa ngokushesha ku-matrix ye-polymer. Futhi, emazingeni okushisa aphansi, ama-molecule amanzi aqina kakhulu ku-matrix ye-HPMC, okuholela ekugcinweni kwamanzi okuphezulu.
Ngakho-ke, kubalulekile ukulawula izinga lokushisa le-ambient phakathi nenqubo yokukhiqiza ukuze kuqinisekiswe ukusebenza okungaguquki nokuthembekile kokugcinwa kwamanzi.
Isakhiwo samangqamuzana
Amandla okugcina amanzi e-HPMC nawo athintwa ukwakheka kwawo kwamangqamuzana. Isakhiwo samangqamuzana e-HPMC sinqunywa izinga lokushintshwa (DS) nokusatshalaliswa kwesisindo samangqamuzana.
Izinga lokushintsha lisho izinga lapho amaqembu e-hydroxyl e-cellulose ashintshwa ngayo amaqembu e-hydroxypropyl. I-HPMC enezinga eliphezulu lokushintsha inamandla okugcina amanzi aphezulu. Ngokuphambene, i-HPMC enezinga eliphansi lokushintsha inamandla aphansi okugcina amanzi.
Ukusatshalaliswa kwesisindo samangqamuzana e-HPMC nakho kuthinta umthamo wokugcina amanzi. Uma ukuphakama kwesisindo sengqamuzana, amandla okugcina amanzi aphakama, njengoba ama-molecule amakhulu akha isakhiwo se-matrix esiqinile esibamba ama-molecule amanzi aqine kakhudlwana.
Ekuphetheni
I-HPMC iyimpahla ezuzisa kakhulu ngenxa yezakhiwo zayo ezinhle kakhulu zokugcina amanzi. Amandla okugcina amanzi e-HPMC ahlobene ngokuqondile ne-viscosity yayo, okuqukethwe, izinga lokushisa elizungezile kanye nesakhiwo samangqamuzana. Ngakho-ke, ukukhetha i-HPMC efanele yohlelo oluthile kudinga ukucatshangelwa ngokucophelela kwalezi zici. Sekukonke, i-HPMC inomthelela omuhle kwikhwalithi nokusebenza kahle kwezinhlobonhlobo zemikhiqizo kuzo zonke izimboni eziningi, okuhlanganisa ezemithi, ukudla, nezokwakha.
Isikhathi sokuthumela: Aug-30-2023