IHydroxypropyl methylcellulose (HPMC) iyisengezo se-polymer esisetshenziswa kakhulu embonini yezokwakha, ikakhulukazi ekukhiqizeni ukhonkolo. Isetshenziswa njenge-ejenti yokujiya, i-ejenti egcina amanzi kanye ne-binder kukhonkolo wengxube emanzi. I-HPMC inenzuzo kukhonkolo ngezindlela ezimbalwa, futhi ukusetshenziswa kwayo kusiza ukunciphisa imifantu yokuncipha kukhonkolo.
Ukuqhekeka kwe-shrinkage kuvame ukwenzeka phakathi nenqubo yokomisa ukhonkolo. Lapho amanzi ehwamuka endaweni kakhonkolo, ukhonkolo uyashwabana. Ukwehliswa kwevolumu kudala izingcindezi eziqinile ezingaholela ekuqhekekeni. Nokho, i-HPMC inciphisa okuqukethwe kwamanzi engxube kakhonkolo, ngaleyo ndlela inciphise ukuhwamuka kwamanzi futhi yehlise inani lokushwabana okwenzeka lapho ukhonkolo woma.
Omunye umsebenzi we-HPMC kukhonkolo ukuthi yenza ifilimu elincanyana phezu kukakhonkolo, okusiza ekunciphiseni ukulahlekelwa kwamanzi okuhwamuka. Ifilimu isiza ukugcina indawo enomswakama ezungeze ukhonkolo, ngaleyo ndlela ithuthukise inqubo yokwelapha. Ukwelapha okuthuthukisiwe kuthuthukisa izakhiwo zikakhonkolo, okuhlanganisa amandla, ukuqina kanye nokumelana nokuqhekeka kokuncipha.
Ukwengeza, i-HPMC ithuthukisa ukusebenza kukakhonkolo, ikwenze kube lula ukuxutshwa nokubeka. Lokhu kuthuthukisa izinga likakhonkolo futhi kunciphisa ingozi yezinkinga ezifana nokuhlukaniswa nokuphuma kwegazi. Lokhu kungenxa yokuthi i-HPMC isebenza njengesithambiso, ekhuthaza ukuxubana okubushelelezi kwezithako kungxube kakhonkolo.
I-HPMC iphinde izuze ukhonkolo ngokuthuthukisa amandla ayo okubopha kanye nokunamathela kwendawo. Uma isetshenziswa enqubweni yokuxuba okomile, i-HPMC iqinisekisa ukuthi ingxube kakhonkolo iyafana nokuthi izithasiselo ezifana nama-aggregate zisatshalaliswa ngokulinganayo kuyo yonke ingxube. Lokhu kusiza ukunciphisa ukushwabana nokuqhekeka kukakhonkolo futhi kuqinisekisa umkhiqizo wokugcina wekhwalithi ephezulu.
I-HPMC futhi inezinye izinzuzo eziyenza ilungele izinhlelo zokusebenza ezikhonkolo. Ayinabuthi futhi iyabola, okwenza ibe umkhiqizo ohambisana nemvelo. Iphinde ibe nempilo yeshelufu ende, iqinisekisa ukuthi igcina ukusebenza kwayo noma igcinwe isikhathi eside. Ukwengeza, kuwumkhiqizo ongabizi kakhulu othuthukisa izakhiwo zekhonkrithi, okwenza kube isengezo esibalulekile embonini yokwakha.
I-HPMC iyisengezo esibalulekile kubuchwepheshe bukasimende besimanje futhi idlala indima ebalulekile ekwehliseni imifantu yokushwabana kukakhonkolo. Izakhiwo zayo ezinhle kakhulu zokubopha kanye nokugcinwa kwamanzi zivumela ukuthi isetshenziselwe ukuthuthukisa izakhiwo ezingokomzimba nezomshini zikakhonkolo. Ngokukhawulela ukushwabana, i-HPMC iqinisekisa ukuthi ikhonkolo igcina ubuqotho bayo besakhiwo, iyenze ibe into ephephile, ehlala isikhathi eside. Ukusetshenziswa kwe-HPMC ekukhiqizeni ukhonkolo kungaba nomthelela omuhle emvelweni, kunciphise izindleko, kuthuthukise ikhwalithi, futhi kuthuthukise ikhwalithi iyonke yesakhiwo. Ngakho-ke, kunconywa kakhulu kunoma iyiphi iphrojekthi yokwakha edinga ukhonkolo oqhekekile ophansi we-shrinkage.
Isikhathi sokuthumela: Sep-19-2023