IHydroxypropyl methylcellulose (HPMC) iyipolymer eguquguqukayo esetshenziswa kabanzi ezimbonini ezahlukahlukene ezihlanganisa ezemithi, ezokudla nezokwakha. Enye yezimpawu zayo ezibalulekile ukugcinwa kwamanzi, okudlala indima ebalulekile ekunqumeni ukusebenza kwawo ezinhlelweni ezahlukene.
1 Isingeniso:
IHydroxypropylmethylcellulose (HPMC) iyi-polymer esekwe ku-cellulose etholakala ku-cellulose yemvelo. Idonse ukunaka ngekhono layo elihle kakhulu lokwenza ifilimu, izakhiwo zokunamathela futhi, okubaluleke kakhulu, izakhiwo zokugcina amanzi. Umthamo wokubamba amanzi we-HPMC uyipharamitha ebalulekile ezisetshenziswayo ezifana nezinto zokwakha, ukwakheka kwemithi, nemikhiqizo yokudla.
2. Ukubaluleka kokugcinwa kwamanzi ku-HPMC:
Ukuqonda izakhiwo zokugcina amanzi ze-HPMC kubalulekile ekuthuthukiseni ukusebenza kwayo ezinhlelweni ezihlukahlukene. Ezintweni zokwakha, kuqinisekisa ukunamathela okufanele nokusebenza kwezinsimbi namapulasi. Kwezemithi, kuthinta amaphrofayili okukhishwa kwezidakamizwa, futhi ekudleni, kuthinta ukuthungwa nempilo yeshelufu.
3. Izinto ezithinta ukugcinwa kwamanzi:
Izinto ezimbalwa zithinta umthamo wokubamba amanzi we-HPMC, okuhlanganisa isisindo samangqamuzana, izinga lokushintsha, izinga lokushisa, nokugxilisa ingqondo. Ukuqonda lezi zici kubalulekile ekuklameni ukuhlola okubonisa ngokunembile izimo zomhlaba wangempela.
4. Izindlela ezijwayelekile zokuhlola ukugcinwa kwamanzi:
Indlela ye-Gravimetric:
Kala amasampula e-HPMC ngaphambi nangemuva kokucwiliswa emanzini.
Bala umthamo wokugcina amanzi usebenzisa ifomula elandelayo: Izinga lokugcinwa kwamanzi (%) = [(Isisindo ngemva kokucwiliswa - Isisindo sokuqala) / Isisindo sokuqala] x 100.
Inkomba yokuvuvukala:
Ukwenyuka komthamo we-HPMC ngemva kokucwiliswa emanzini kukalwa.
Inkomba yokuvuvukala (%) = [(ivolumu ngemva kokucwiliswa - ivolumu yokuqala)/ivolumu yokuqala] x 100.
Indlela ye-Centrifugation:
I-Centrifuge ingxube ye-HPMC-amanzi futhi ulinganise umthamo wamanzi agciniwe.
Izinga lokugcinwa kwamanzi (%) = (umthamo wokugcina amanzi / umthamo wamanzi wokuqala) x 100.
I-Nuclear Magnetic Resonance (NMR):
Ukusebenzisana phakathi kwe-HPMC nama-molecule amanzi kwacwaningwa kusetshenziswa i-NMR spectroscopy.
Thola imininingwane ngezinguquko zeleveli yamangqamuzana ku-HPMC ngesikhathi sokuthatha amanzi.
5. Izinyathelo zokuhlola:
Ukulungiselela Isampula:
Qinisekisa ukuthi amasampula e-HPMC amele uhlelo oluhlosiwe.
Lawula izinto ezifana nosayizi wezinhlayiyana kanye nomswakama.
Ukuhlolwa kwesisindo:
Kala ngokunembile isampula ye-HPMC elinganisiwe.
Gxilisa isampula emanzini ngesikhathi esishiwo.
Isampula yomiswa futhi isisindo salinganiswa futhi.
Bala ukugcinwa kwamanzi.
Isilinganiso senkomba yokunwetshwa:
Linganisa ivolumu yokuqala ye-HPMC.
Gxilisa isampula emanzini bese ukala ivolumu yokugcina.
Bala inkomba yokunweba.
Ukuhlolwa kwe-Centrifuge:
Xuba i-HPMC namanzi futhi uvumele ukulinganisa.
I-Centrifuge ingxube futhi ulinganise umthamo wamanzi agciniwe.
Bala ukugcinwa kwamanzi.
Ukuhlaziywa kwe-NMR:
Ukulungiswa kwamasampuli e-HPMC-amanzi okuhlaziya i-NMR.
Hlaziya izinguquko ekushintsheni kwamakhemikhali kanye nokuqina okukhulu.
Ukuhlobanisa idatha ye-NMR nezakhiwo zokugcina amanzi.
6. Ukuhlaziywa nokuhumusha idatha:
Chaza imiphumela etholwe ngendlela ngayinye, ucabangela izidingo ezithile zohlelo lokusebenza. Qhathanisa idatha evela ezindleleni ezahlukene ukuze uthole ukuqonda okuphelele kokuziphatha kokugcinwa kwamanzi kwe-HPMC.
7. Izinselelo nokucatshangwayo:
Xoxa ngezinselele ezingaba khona ekuhloleni ukugcinwa kwamanzi, njengokuhlukahluka kwamasampula e-HPMC, izimo zemvelo, kanye nesidingo sokumiswa.
8. Isiphetho:
Okutholakele okuyinhloko kufingqiwe futhi ukubaluleka kokuqonda izakhiwo zokugcina amanzi ze-HPMC ukuze kusetshenziswe ngempumelelo ezimbonini ezihlukahlukene kuyagqanyiswa.
9.Amathemba esikhathi esizayo:
Intuthuko engaba khona ezindleleni nezindlela zokuhlola kuxoxwa ngazo ukuze kuthuthukiswe ukuqonda kwethu izici zokugcinwa kwamanzi ze-HPMC.
Isikhathi sokuthumela: Dec-11-2023