Kutheni i-HEMC ilukhetho olungcono kune-HPMC?

I-Hypromellose (HPMC) kunye ne-hydroxyethylmethylcellulose (HEMC) zimbini ezisetyenziswa ngokubanzi kwi-cellulose derivatives kunye nezicelo kumashishini amayeza, ukutya kunye ne-cosmetic. Nangona i-HPMC kunye ne-HEMC babelana ngezinto ezininzi ezifanayo, ziyahluka ngeendlela ezithile, zenza enye ibe phezulu kunezinye izicelo ezithile.

I-HEMC yi-ether ye-cellulose eguqulwayo efunyenwe ngokuphendula i-methyl cellulose kunye ne-ethylene oxide kunye ne-ethyl chloride, kwaye emva koko ithatha indawo ye-ethyl ye-hydroxyl. Ngoko ke, i-HEMC inezinga eliphezulu lokuthatha indawo (DS) kune-HPMC. I-DS ibhekisa kwi-avareji yenani le-substituent kwiyunithi nganye ye-glucose, echaphazela i-physical and chemical properties of the polymer. Ngokubanzi, i-DS ephezulu ikhokelela ekunyibilikeni okungcono kwizinyibilikisi zezinto eziphilayo, amazinga okupheliswa okukhawulezayo, kunye nokuthambekela okwandisiweyo okufunxa amanzi. I-DS ye-HEMC idla ngokuba yi-1.7-2.0, ngelixa i-DS ye-HPMC idla ngokuba phakathi kwe-1.2 kunye ne-1.5.

Uncedo olwahlukileyo lwe-HEMC ngaphezu kwe-HPMC lugcino lwamanzi olugqwesileyo, luyenza ilungele ukwakheka kokuncamathelisa, imathiriyeli yokwakha kunye nezinye iimveliso ezifuna ukugcinwa kakuhle kwamanzi. I-HEMC ikwazi ukumelana nohlaselo lwe-microbial kune-HPMC kwaye inobomi obude beshelufu. Ukunyuka kwe-hydrophobicity ye-HEMC kunye nobukho bamaqela e-ethyl kwi-backbone yayo yenza i-emulsifier egqwesileyo kwaye inokuphucula ukuzinza kwexesha elide le-emulsions.

Olunye uncedo lokusebenzisa i-HEMC kukuhambelana kwayo nezinye iikhemikhali ezininzi, ezinegalelo ekuguquguqukeni kwayo kwizicelo ezahlukeneyo. Ukongezelela, i-HEMC ineempawu ezintle zokwenza ifilimu, ezenza kube luncedo ukuveliswa kweengubo kunye nezibophelelo ekuveliseni iipilisi, iipilisi kunye neegranules.

Kwelinye icala, i-HPMC ineempawu ezingcono ze-thermal gelling, nto leyo eyenza ukuba ibe lolona khetho lubalaseleyo kumayeza okwenziwa ngokucothayo afuna ijeli ezingeva lubushushu. I-HPMC nayo inonyibiliko olungcono lwamanzi kwaye ayithandeki kangako ekwenzeni i-coagglomerate, ezizii-aggregates ezinganyibilikiyo zeepholima kwisisombululo.

Ukuqukumbela, zombini i-HEMC kunye ne-HPMC zizinto eziphuma kwi-cellulose ezixabisekileyo ezibonelela ngeenzuzo ezahlukeneyo ngokuxhomekeke kwisicelo. I-HEMC inokugcinwa kwamanzi ngcono, i-emulsification, kunye nokuhambelana nezinye iikhemikhali, ngelixa i-HPMC ineempawu ezibalaseleyo ze-thermogelling kunye nokunyibilika kwamanzi. Ngoko ke, ukhetho phakathi kwe-HEMC kunye ne-HPMC luxhomekeke kwisicelo esifunwayo, inkqubo yokuvelisa kunye neemfuno zokugqibela zemveliso.