Ngubani umenzi we-hypromellose?

I-Kima Chemical inikeza uluhlu olubanzi lweemveliso ze-hypromellose ukuhlangabezana neemfuno zezicelo ezahlukeneyo. Iimveliso ze-hypromellose zenkampani zifumaneka kumabakala ahlukeneyo e-viscosity kunye ne-degrees of substitution (DS), kunye neendlela ezenziwe ngokwezifiso ukuhlangabezana neemfuno ezithile zabathengi.

Iimveliso ze-hypromellose zeKima Chemical zenziwa kusetyenziswa itekhnoloji yokuvelisa ephucukileyo kunye nemilinganiselo engqongqo yokulawula umgangatho ukuqinisekisa umgangatho ongaguqukiyo kunye nokusebenza. Iimveliso ze-hypromellose zenkampani nazo zihambelana nemigangatho eyahlukeneyo yamazwe ngamazwe, kuquka i-USP, i-EP, i-JP, kunye ne-FCC.

IHypromellose yipolymer eguquguqukayo esetyenziswa kuluhlu olubanzi lwamashishini. I-Kima Chemical ngumenzi ohamba phambili we-hypromellose, enika uluhlu olubanzi lwamabakala kunye neenkcukacha zokuhlangabezana neemfuno zezicelo ezahlukeneyo. Iimveliso ze-hypromellose zeKima Chemical zenziwa kusetyenziswa itekhnoloji yokuvelisa ephucukileyo kunye nemilinganiselo engqongqo yokulawula umgangatho ukuqinisekisa umgangatho ongaguqukiyo kunye nokusebenza. Ngeempawu zayo ezintle kunye noluhlu olubanzi lwezicelo, i-hypromellose iyisithako esibalulekileyo kwiimveliso ezininzi kunye namashishini.

IHypromellose, ekwaziwa ngokuba yi-hydroxypropyl methylcellulose (HPMC), i-semi-synthetic polymer esetyenziswa kuluhlu olubanzi lwamashishini. Yenziwe ngokuguqula i-cellulose, i-polymer yendalo efumaneka kwizityalo. I-Hypromellose isetyenziswa ngokuqhelekileyo njenge-thickener, emulsifier, kunye ne-stabilizer kwishishini lokutya, kwaye njenge-binder, ifilimu-yangaphambili, kunye ne-lubricant kumashishini amayeza. I-Kima Chemical ngumenzi ohamba phambili we-hypromellose, enika uluhlu olubanzi lwamabakala kunye neenkcukacha zokuhlangabezana neemfuno zezicelo ezahlukeneyo.

Ulwakhiwo lweMichiza yeHypromellose

Hypromeloseyipolima enyibilikayo emanzini ephuma kwiselulosi. Yenziwe ngokuphendula i-cellulose kunye nepropylene oxide kunye ne-methyl chloride. I-polymer ebangelwayo inomlinganiselo we-molecular weight of 10,000 ukuya kwi-1,000,000 ye-Daltons, kuxhomekeke kwiqondo lokutshintshwa (DS) kunye nebakala le-viscosity.

Ubume bekhemikhali be-hypromellose bubandakanya umqolo we-cellulose kunye ne-hydroxypropyl kunye namaqela e-methyl aqhotyoshelwe kwiiyunithi ze-anhydroglucose. Iqondo lokutshintsha (DS) libhekisa kumndilili wenani le-hydroxypropyl kunye namaqela e-methyl ngeyunithi ye-anhydroglucose. I-DS inokuvela kwi-0.1 ukuya kwi-2.5, kuxhomekeke kwiipropati ezifunwayo ze-hypromellose.

Iipropati zeHypromellose

IHypromellose ngumgubo omhlophe ukuya kumhlophe ongenavumba kwaye ongenancasa. Iyanyibilika emanzini nakwizinyibilikisi ezininzi eziphilayo, kodwa ayinyibiliki kuninzi lwezinyibilikisi ezingezizo ipolar. I-Hypromellose ine-viscosity ephezulu kwindawo ephantsi, eyenza ibe yinto esebenzayo kunye ne-binder. Ikwanazo neempawu ezigqwesileyo zokwenza ifilimu, ezenza kube luncedo ekuveliseni iingubo kunye neefilimu.

Iimpawu ze-hypromellose zixhomekeke kwiqondo lokutshintshela (DS) kunye nebakala le-viscosity. Amanqanaba aphezulu e-DS ane-solubility enkulu yamanzi kunye nokushisa okuphantsi kwe-gelation, ngelixa amanqanaba aphantsi e-DS anobushushu obuphezulu be-gelation kunye nokuzinza okungcono kwe-thermal. Ibakala le-viscosity limisela ubukhulu besisombululo se-hypromellose kunye nokukwazi ukwenza iigels.

Ukusetyenziswa kweHypromellose

IHypromellose isetyenziswa kuluhlu olubanzi lwamashishini, kubandakanya ukutya, amayeza, izinto zokuthambisa kunye nokwakha. Kwishishini lokutya, i-hypromellose isetyenziswa njenge-thickener, emulsifier, kunye ne-stabilizer kwiimveliso ezahlukeneyo, kubandakanya i-ayisikrimu, i-sauces, kunye neempahla ezibhakiweyo. Kumashishini amayeza, i-hypromellose isetyenziswa njenge-binder, ifilimu-yangaphambili, kunye ne-lubricant kwiipilisi, ii-capsules, kunye ne-ointments. Ikwasetyenziswa njenge-ejenti yokwambathisa kwimiqulu elawulwayo yokukhutshwa.

Kwishishini lezithambiso, i-hypromellose isetyenziswa njenge-thickener, emulsifier, kunye nefilimu-yangaphambili kwizinto zokuthambisa, iikhrimu kunye neemveliso zokuthambisa. Kwishishini lokwakha, i-hypromellose isetyenziswa njenge-thickener kunye ne-binder kwiimveliso ezisekelwe kwi-samente, ezifana nodaka kunye ne-grouts.