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Ziziphi izinto ezinxulumene ne-viscosity ye-hydroxypropyl methylcellulose isisombululo se-aqueous?

I-Hydroxypropylmethylcellulose (HPMC) i-polymer e-soluble yamanzi ephuma kwi-cellulose yendalo kwaye isetyenziswa ngokubanzi kumashishini amaninzi ngenxa yokukwazi ukuvelisa uluhlu lwe-viscosities kwizisombululo zamanzi. I-HPMC inoluhlu olubanzi lwezicelo kumashishini amayeza, ukutya kunye nezithambiso. I-Viscosity luphawu oluphambili lwezisombululo ze-HPMC ezichaphazela ukusebenza kwazo kwezi zicelo.

Izinto ezichaphazela i-viscosity:

1. Ugxininiso: Ukugxininiswa kwe-HPMC kwisisombululo kuhambelana ngqo ne-viscosity yesisombululo. Njengoko uxinaniso lwe-HPMC lusanda, i-viscosity yesisombululo iyanda njengoko amakhonkco e-polymer ebambene ngakumbi. Nangona kunjalo, ugxininiso oluphezulu kakhulu lunokubangela isisombululo esiqinileyo kunye nejeli, esinokuthi singanqweneleki kwezinye izicelo.

2. Ubunzima bemolekyuli: Ubunzima bemolekyuli ye-HPMC yinto ephambili echaphazela i-viscosity yesisombululo. Njengoko ubunzima bemolekyuli be-HPMC bukhula, i-viscosity yesisombululo nayo iyanda ngenxa yokunyuka kokuphonswa kwamakhonkco e-polymer. I-HPMC enobunzima obuphezulu bemolekyuli inamatyathanga amade, okukhokelela kwisisombululo se-viscous.

3. Ubushushu: I-viscosity yesisombululo se-HPMC nayo ichaphazeleka ngubushushu. Njengoko ubushushu besisombululo sanda, i-viscosity yesisombululo iyancipha. Ukuncipha kwe-viscosity kungenxa yokuncipha kwamandla e-intermolecular phakathi kwamatyathanga e-polymer, okukhokelela ekubambeni okuncinci kunye nokwanda kwe-fluidity.

4. Ixabiso le-pH: Ixabiso le-pH lesisombululo liya kuchaphazela kwakhona i-viscosity yesisombululo se-HPMC. Amaxabiso e-pH angaphandle koluhlu lwe-5.5-8 anokubangela ukuhla kwe-viscosity ngenxa yotshintsho kwi-solubility kunye nentlawulo ye-polymer ye-HPMC.

5. Ubutyuwa: Ubutyuwa okanye amandla e-ionic esisombululo nawo achaphazela i-viscosity yesisombululo se-HPMC. Ukwandisa ityuwa yetyuwa kuphazamisa i-HPMC i-polymer chain interactions, okukhokelela ekunciphiseni kwe-viscosity yesisombululo.

6. Iimeko zokucheba: Iimeko zokucheba apho isisombululo se-HPMC sibonakaliswe siya kuchaphazela i-viscosity yesisombululo. Iimeko ze-shear zingabangela ukuhla kwexeshana kwi-viscosity, njengokuba ngexesha lokuxuba okanye ukupompa isisombululo. Emva kokuba imeko ye-shear isusiwe, i-viscosity ibuyela ngokukhawuleza kwisimo esizinzileyo.

ukuququmbela:

I-viscosity ye-HPMC izisombululo zamanzi zichatshazelwa zizinto ezahlukeneyo ekufuneka ziqwalaselwe xa kuqulunqwa imveliso. Ukugxila, ubunzima bemolekyuli, ubushushu, i-pH, ityuwa, kunye neemeko zokucheba zezona zinto zibalulekileyo ezichaphazela i-viscosity yezisombululo ze-HPMC. Ukuqonda ezi zinto kunokunceda abavelisi baphucule i-viscosity yezisombululo ze-HPMC kwizicelo ezithile. I-Viscosity luphawu olubalulekileyo lwezisombululo ze-HPMC njengoko inokumisela ukusebenza kunye nokuzinza kweemveliso ezisekelwe kwi-HPMC.


Ixesha lokuposa: Oct-16-2023
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