I-Hydroxypropylmethylcellulose (HPMC) yi-polymer esekwe kwi-cellulose esetyenziswa ngokubanzi njenge-thickener, i-binder kunye ne-stabilizer kwizicelo ezahlukeneyo zoshishino, kubandakanywa noshishino lokwakha. Kwikhonkrithi, i-HPMC isetyenziswa ikakhulu njenge-arhente yokugcina amanzi kunye nesixhasi sokusebenza, esinokuphucula ukusebenza kunye nokuqina kwekhonkrithi. Isixa se-HPMC esisetyenziswe kwikhonkrithi sibalulekile ukuphumeza umphumo ofunekayo.
Isixa se-HPMC esifunekayo kwikhonkrithi sixhomekeke kwisicelo esithile, uhlobo lwesamente esetyenziswayo kunye neemeko zokusingqongileyo. Ngokuqhelekileyo, inani le-HPMC elisetyenzisiweyo livela kwi-0.1% ukuya kwi-0.5% yesisindo esipheleleyo se-samente kumxube. Nangona kunjalo, isixa esichanekileyo kufuneka sinqunywe ngokweempawu ezifunwayo kunye nokusebenza kwekhonkrithi.
Enye yeenzuzo eziphambili zokusebenzisa i-HPMC kwikhonkrithi kukukwazi ukuphucula ukusebenza komxube. I-HPMC isebenza njenge-lubricant, inciphisa ingxabano phakathi kwamasuntswana kwisamente kwaye inceda umxube uhambe kakuhle. Oku kwandisa ukusebenza kwekhonkrithi, okwenza kube lula ukubeka kunye nokubumba ngomzamo omncinci kunye nomzamo. Ukongeza, i-HPMC inokunceda ukunciphisa ubungakanani bamanzi afunekayo kumxube, ukuphucula inkqubo ye-hydration kunye namandla kunye nokuqina kwekhonkrithi ephilileyo.
Enye inzuzo ye-HPMC kwikhonkrithi kukukwazi ukugcina amanzi. I-HPMC yenza ijeli-efana nesakhiwo esinokubamba iimolekyuli zamanzi, zithintele ukuba zingabi ngumphunga okanye zifunxwe yi-substrate engqongileyo. Oku kunceda ukukhusela ubuso bekhonkrithi ukuba bome kunye nokuqhekeka kwangaphambi kwexesha, okunokuphazamisa ukuqina kwayo kunye nobuhle.
I-HPMC inokuphucula ukunamathela kunye nokusebenza kokudibanisa kwekhonkrithi. Xa yongezwa kumxube, i-HPMC yenza ifilimu egubungela umphezulu weengqungquthela zesamente, inceda ukubopha kunye nokwenza isakhiwo esidibeneyo. Oku kwandisa amandla omatshini kunye nokuqina kwekhonkrithi, okwenza kube nzima ukuchasa, ukukrazula kunye nezinye iindlela zomonakalo.
Ukuqinisekisa ukusetyenziswa okusebenzayo nokukhuselekileyo kwe-HPMC kwikhonkrithi, kubalulekile ukulandela izikhokelo ezithile kunye nezenzo ezingcono. I-HPMC kufuneka yongezwe kumxube ngokucothayo nangokulungeleleneyo, ngokukhethekayo kusetyenziswa umxube womatshini, ukuqinisekisa ukuba ihlakazwe kakuhle kwaye ifakwe kumxube. Ukuhambelana kunye nokusebenza komxube kufuneka kuhlolwe ngamaxesha kwaye kulungiswe njengoko kuyimfuneko ukufezekisa iimpawu ezifunwayo kunye nokusebenza.
Kwakhona kubalulekile ukusebenzisa i-HPMC ekumgangatho ophezulu eyenzelwe ikhonkrithi. I-HPMC kufuneka ithathwe kubaboneleli abathembekileyo kwaye ivavanyelwe umgangatho kunye nokucoceka ukuqinisekisa ukuba iyahlangabezana nemigangatho efunekayo kunye neenkcukacha. Ukugcinwa ngendlela eyiyo kunye nokuphathwa kwe-HPMC kukwabalulekile ukuthintela ukosuleleka okanye ukuthotywa okunokuphazamisa ukusebenza kwayo kunye nokusebenza kwayo.
Ngokubanzi, ukusetyenziswa kwe-HPMC ekuqulunqweni kwekhonkrithi kuphucula ukusetyenzwa, ukugcinwa kwamanzi, kunye neempawu zokubopha umxube, okubangela ukuba kubekho ixesha elide, elinamandla, kunye nomgangatho ophezulu wekhonkrithi. Ngokulandela iindlela ezifanelekileyo kunye nezikhokelo, kunye nokusebenzisa i-HPMC ephezulu, abakhi kunye neenjineli banokufikelela kwiziphumo ezinqwenelekayo kwaye baqinisekise ukusebenza kwexesha elide kunye nokuthembeka kwezakhiwo zabo eziphathekayo.
Ixesha lokuposa: Aug-03-2023