ukwazisa
IHydroxypropyl methylcellulose (HPMC) yi-ether eselulosi enyibilikayo emanzini edla ngokusetyenziswa kwizicelo ezahlukeneyo ezinjengokwakha, ukutya, amayeza kunye nezithambiso ngenxa yeempawu zayo ezizodwa ezinjengokugcina amanzi, ukujiya kunye nobuchule bokwenza ifilim. Iimpawu zokugcina amanzi ze-HPMC zibaluleke kakhulu kulwakhiwo njengoko kunceda ukuphucula ukusebenza, ukunciphisa ukuqhekeka kunye nokwandisa ukusebenza kwemathiriyeli esekwe kwisamente. Ke ngoko, ukulinganisa ngokuchanekileyo umthamo wokugcina amanzi we-HPMC kubalulekile ukuqinisekisa umgangatho wemveliso yokugqibela. Kweli nqaku, siza kuxubusha indlela yokuvavanya ukugcinwa kwamanzi ye-HPMC kunye nokubaluleka kwayo kushishino lokwakha.
Indlela yokuvavanya ukugcinwa kwamanzi
Umthamo wokubamba amanzi we-HPMC ulinganiswa ngobungakanani bamanzi i-HPMC enokuwagcina ngexesha elithile. Zininzi iindlela zokuvavanya ugcino lwamanzi lwe-HPMC, eyona ndlela isetyenziswa kakhulu yindlela ye-centrifugation. Indlela inamanyathelo amathathu aphambili:
Inyathelo 1: Ukulungiselela iSampuli
Inyathelo lokuqala kukulungiselela isampuli HPMC. Ukulinganisa umlinganiselo othile we-HPMC powder kwangaphambili kwaye wongeze umlinganiselo othile wamanzi ukwenza i-slurry. Umlinganiselo we-HPMC kumanzi uyahluka ngokuxhomekeke kwiimfuno ezithile zesicelo kunye novavanyo. Nangona kunjalo, umlinganiselo oqhelekileyo yi-0.5% HPMC kumanzi ngobunzima. I-slurry kufuneka ishukunyiswe imizuzu emininzi ukuqinisekisa ukuba i-HPMC isasazwe ngokulinganayo emanzini. Emva koko, vumela i-slurry ihlale iiyure ezili-12 ukuqinisekisa ukuba i-hydrated ngokupheleleyo.
Inyathelo 2: I-Centrifuge
Emva kweeyure ze-12, susa i-slurry kwaye ubeke ubunzima obaziwayo be-slurry kwi-tube ye-centrifuge. Emva koko ityhubhu ifakwe kwi-centrifuge kwaye ijikelezwe ngesantya esithile kwixesha elimiselweyo. Isantya kunye nobude be-centrifugation inokwahluka ngokuxhomekeke kwindlela ekhethiweyo. Ngokuqhelekileyo, isantya se-centrifuge yi-3000rpm kwaye ixesha lokuvavanya yimizuzu engama-30. Nangona kunjalo, imigangatho eyahlukeneyo inokufuna isantya kunye nobude obahlukeneyo.
Inyathelo lesi-3: Ukubalwa kwexabiso lokugcinwa kwamanzi
Emva kwe-centrifugation, susa ityhubhu kwaye uhlukanise amanzi kwi-HPMC. Ixabiso lokugcinwa kwamanzi lingabalwa ngolu hlobo lulandelayo:
Ixabiso lokugcinwa kwamanzi = [(HPMC + ubunzima bamanzi phambi kwe-centrifugation) - (HPMC + ubunzima bamanzi emva kwe-centrifugation)] / (HPMC + ubunzima bamanzi phambi kwe-centrifugation) x 100
Ixabiso lokugcinwa kwamanzi libonisa ubungakanani bamanzi agcinwe yi-HPMC emva kwe-centrifugation.
Ukubaluleka kovavanyo lokugcinwa kwamanzi kulwakhiwo
Uvavanyo lokugcinwa kwamanzi lubalulekile kushishino lokwakha njengoko lunceda ekuqinisekiseni ukuba imveliso yokugqibela ikumgangatho ofanayo kwaye ihlangabezana neenkcukacha ezifunekayo. I-HPMC isetyenziswa ngokuqhelekileyo kwizinto ezisekelwe kwisamente ezifana nodaka, i-grout kunye nekhonkrithi ukuphucula ukusebenza kwazo, ukunciphisa ukucutheka kunye nokwandisa ukuqina kwazo. Iipropati zokugcina amanzi ze-HPMC zidlala indima ebalulekileyo ekuphumezeni ezi zibonelelo.
Ixabiso lokugcinwa kwamanzi kwe-HPMC limisela ubungakanani bamanzi anokugcinwa kwimathiriyeli esekwe kwisamente, enegalelo ekusebenzeni kwayo. Izixhobo zesamente ezinamaxabiso aphezulu okugcina amanzi zinokwenzeka kwaye kulula ukuxuba kunye nokusebenzisa. Ukongezelela, izinto eziphathekayo ezinexabiso eliphezulu lokugcinwa kwamanzi zineepokotshi zomoya ezincinci, ezinciphisa amathuba okuqhekeka kunye nokwandisa ukuqina okupheleleyo kwezinto.
Ukongezelela, ixabiso lokugcinwa kwamanzi kwe-HPMC luphawu lomgangatho we-HPMC esetyenziswe kwizinto eziphathekayo. I-HPMC eneempawu ezifunekayo zokugcina amanzi iqinisekisa ukusebenza kwexesha elide lezinto zokwakha. Ngokwahlukileyo, i-HPMC enexabiso eliphantsi lokugcinwa kwamanzi kunokukhokelela kwiipropati ezingonelanga zokwakha, ukudibanisa okungahambi kakuhle kunye nokushwabana, ekugqibeleni kukhokelela ekungaphumeleli kwezinto zokwakha.
ukuququmbela
Uvavanyo lokugcinwa kwamanzi luyinto ephambili ekumiseleni umgangatho we-HPMC osetyenziswa kushishino lokwakha. Olu vavanyo lunceda ukulinganisa ngokuchanekileyo iipropati zokugcina amanzi ze-HPMC ukuqinisekisa ukuba iyahlangabezana neemfuno ezithile zesicelo esinikiweyo. I-HPMC inokugcinwa kwamanzi aphezulu, ibonelela ngokusebenza okuphuculweyo, ukudibanisa okuphuculweyo, ukuqhekeka okuncitshisiweyo kunye nokuqina okwandisiweyo kwizinto zesamente. Ngoko ke, kushishino lokwakha, kuyimfuneko ukuqhuba iimvavanyo zokugcina amanzi kwi-HPMC ukuqinisekisa umgangatho wemveliso yokugqibela.
Ixesha lokuposa: Sep-18-2023