Inkqubo yokuhamba kwe-hydroxypropyl methylcelcelceluplose

Hydroxypropyl methylcelculose (hpmc)sisiseko esiqhelekileyo se-selsulose esetyenziswa ngamanzi, esetyenziswa ngokubanzi ekwakhiweni, iingubo, amayeza, ukutya kunye ne-cosmetics. Inkqubo yayo yemveliso inzima kwaye ibandakanya amanyathelo amaninzi, ikakhulu kubandakanya ukupheliswa, ukuphendula, ukuhlamba, ukomisa kwaye kutyumlwe i-sellyulose.

I-1. Ukulungiselela izinto ezibonakalayo

Ukuveliswa kwe-hydroxypropyl methylcelcelgalose isebenzisa izityalo ezinjengeenkuni okanye zomqhaphu njengezixhobo eziluhlaza. Okokuqala, i-seluplose kufuneka ikhutshwe kwisityalo. I-selsulose ekhutshiweyo ayisekelwanga, i-bleid, kunye nenqaba esuswe ukufumana izinto ezihlambulukileyo.

I-2. Ukuchithwa kwe-seluplose

I-sellyulose ine-solity elihlwempuzekileyo emanzini, ngoko ke kufuneka ichithwe nge-solvent ngexesha lenkqubo yemveliso. Iifoto eziqhelekileyo ngumxube we-Ammoium chloride kunye namanzi, okanye umxube we-ammonia ne-ethanol. Okokuqala, i-seluplose emsulwa ixutywe ne-Solvent kwaye inyangwe kubushushu obuphezulu ukuqinisekisa ukuba i-Selelose inokuchithwa ngokupheleleyo.

I-3. Impendulo ye-methyy

Iarhente ye-methylating (efana ne-methyl chloride okanye i-methyl chloride yongezwa kwiseloko inyibilikisiwe kwiselokonketha. Eyona njongo iphambili yale mpendulo kukwazisa amaqela e-methyl (-och₃) ukwenza i-methyl sellulose. Le nkqubo ngokubanzi kufuneka yenziwe kwindawo ye-alkaline, kunye nolawulo lobushushu kunye nexesha linempembelelo ebalulekileyo kwisakhiwo semolekyuli kunye nokusebenza kwemveliso yokugqibela.

4. I-Hydroxyproplopy

I-methyuple seluplose iphinda iphinde iphinde iphinde iphinde iphinde isebenze ngama-acrylates (njenge-allyl chloride) ukwazisa amaqela e-hydroxypropyl (-och₂ch₃). Le mpendulo idla ngokuqhutywa kwesisombululo se-alkaline, kunye nolawulo lobushushu bendlela yokuzama kunye nokuphendula kugqiba umxholo we-hydroxypropy yemveliso. Inqanaba le-hydroxyyprovyplopy ichaphazela ngokuthe ngqo ukuluka, i-viscosity kunye nezinye iipropathi zomzimba kunye neekhemikhali ze-HPMC.

I-5. Ukungathathi cala kunye nokuhlamba

Emva kokuphendula kugqityiwe, ezinye izinto zeAlkaline okanye ukuphinda-phinda kwemichiza ezingasebenziyo kunokuhlala kwinkqubo. Ke ngoko, kuyimfuneko ukususa izinto ezigqithisileyo ze-alkaline ngonyango lokungathathi cala. Ukungathathi cala kuhlala kuqhutywa nge-acid (njenge-acetic acid okanye i-hydrochloric acid), kwaye ityuwa engathathi hlangothi iya kuveliswa emva kwesabelo esisesiseko. Emva koko, ukungcola kwisisombululo kuyasuswa ngokuhlanjwa okuninzi ukuqinisekisa ukucoceka kwemveliso.

I-6. Ukupheliswa komzimba kunye nokomisa

Isisombululo saseSelesel Selelose kufuneka sikhutshiwe, kwaye ukubengezela okanye ukupheliswa kudla ngokusetyenziswa ukususa amanzi. Ukumiswa kwempahla yeselfowuni enesidima kuqukethe uxinzelelo oluphezulu lwento eyomileyo, kwaye ingena kwinkqubo yokomisa. Indlela yokomisa inokuba yi-spy yokutshiza, i-vacuum yomile okanye yomisa umoya ovuthayo. Ulawulo lobushushu ngexesha lenkqubo yokomisa kubaluleke kakhulu. Iqondo lokushisa elikhulu kakhulu linokubangela ukuba imveliso ikhuphe okanye ilahlekelwe ngumsebenzi wayo.

I-7. Ukutyumza kunye nokuzibopha

I-Hydroplopyl ye-Hydropyl ye-HydylcelceLcelose ikwimo yomgubo kwaye kufuneka ityunyuzwe kwaye isuswe ukuze ilawule ubungakanani bemveliso yemveliso kwimveliso ethile. Inkqubo yokuhleba inokuqinisekisa ukufana kwemveliso kwaye isuse ukungcola ngamasuntswana amakhulu.

I-8. Ukupakisha kunye nokugcina

I-hydroxypropyl methylcelcelsulose invenetion iveliswa kwiifom ezahlukeneyo zokupakisha ngokweemfuno zomthengi, ezinjengeebhanti, njl njl. Imveliso ephangelweyo kufuneka igcinwe kwindawo eyomileyo neyinopholileyo ukuthintela ubushushu obuphezulu kunye nokufuma.

9. Ulawulo loMgangatho

Ulawulo olusemgangathweni olungqongqo luyafuneka kwikhonkco ngalinye kwinkqubo yemveliso ukuqinisekisa ukuba imveliso yokugqibela ihlangabezana nemigangatho. Izinto zovavanyo oluqhelekileyo zibandakanya: Solula, i-viscosity, ixabiso le-pl, umxholo ongcolileyo kunye nomswakama. Iipropathi zemveliso zichaphazela ngqo ukusebenza kwayo kwiinkalo ezahlukeneyo zezicelo, ulawulo olusemgangathweni sisixhobo esiphambili kwimveliso ye-HydroxlyPOse.

Inkqubo yemveliso yehydroxypropyl methylcelceluploseKubandakanya ukuphendula ezininzi zekhemikhali kunye namanyathelo onyango onyango, kwaye ineemfuno eziphezulu zeemeko zenkqubo. Iqondo lokushisa, ixesha, ixabiso le-pH kunye nezinye izinto kufuneka zilawulwe ngokungqongqo kwimveliso yokufumana iimveliso ezinentsebenzo efanelekileyo. Ngokuqhubela phambili kwezenzululwazi nobugcisa kunye nophuhliso lwetekhnoloji yemveliso, inkqubo yemveliso ye-HPMC ihlala iphucula, kwaye ibala lesicelo lemveliso liyanda.