ibakala Pharmaceutical HPMC
Ibakala lonyango lwe-HPMC Hydroxypropyl methylcellulose imhlophe okanye i-milky emhlophe, ayinavumba, ayinancasa, i-fibrous powder okanye igranule, ukwehla kobunzima xa isomiswa akudluli kwi-10%, inyibilika emanzini abandayo kodwa hayi amanzi ashushu, kancinci emanzini ashushu Ukudumba, ukudumba, kunye nokwenza a isisombululo se-viscous colloidal, esiba sisisombululo xa sipholile, kwaye sibe yijeli xa ishushu. I-HPMC ayinyibiliki kwi-ethanol, i-chloroform kunye ne-ether. Inyibilika kwi-solvent edibeneyo ye-methanol kunye ne-methyl chloride. Ikwanyibilika kwisinyibilikisi esixubeneyo se-acetone, i-methyl chloride kunye ne-isopropanol kunye nezinye izinyibilikisi eziphilayo. Isisombululo saso samanzi sinokunyamezela ityuwa (isisombululo sayo se-colloidal asitshabalaliswa yityuwa), kwaye i-pH ye-1% yesisombululo samanzi ngu-6-8. I-molecular formula ye-HPMC yi-C8H15O8-( C10H18O6) -C815O, kwaye ubunzima be-molecular mass malunga ne-86,000.
Ukucaciswa kwemichiza
| I-HPMC yezamayeza Inkcazo | HPMC 60E( 2910) | HPMC 65F(2906) | HPMC 75K( 2208) |
| Ubushushu beGel (℃) | 58-64 | 62-68 | 70-90 |
| I-Methoxy (WT%) | 28.0-30.0 | 27.0-30.0 | 19.0-24.0 |
| IHydroxypropoxy (WT%) | 7.0-12.0 | 4.0-7.5 | 4.0-12.0 |
| Viscosity(cps, 2% Solution) | 3, 5, 6, 15, 50, 100, 400,4000, 10000, 40000, 60000, 100000, 150000, 200000 | ||
Ibanga leMveliso:
| I-HPMC yezamayeza Inkcazo | HPMC 60E( 2910) | HPMC 65F(2906) | HPMC 75K( 2208) |
| Ubushushu beGel (℃) | 58-64 | 62-68 | 70-90 |
| I-Methoxy (WT%) | 28.0-30.0 | 27.0-30.0 | 19.0-24.0 |
| IHydroxypropoxy (WT%) | 7.0-12.0 | 4.0-7.5 | 4.0-12.0 |
| Viscosity(cps, 2% Solution) | 3, 5, 6, 15, 50, 100, 400,4000, 10000, 40000, 60000, 100000, 150000, 200000 | ||
Isicelo
| Isicelo se-Pharma Excipients | IBanga loShishino lwe-HPMC | Umthamo |
| I-Laxative eninzi | 75K4000,75K100000 | 3-30% |
| Iikhremu, iiGel | 60E4000,75K4000 | 1-5% |
| Ukulungiswa kwamehlo | 60E4000 | 01.-0.5% |
| Amalungiselelo amathontsi eliso | 60E4000 | 0.1-0.5% |
| I-arhente yokunqumamisa | 60E4000, 75K4000 | 1-2% |
| Ii-antacids | 60E4000, 75K4000 | 1-2% |
| Iitafile zeBinder | 60E5, 60E15 | 0.5-5% |
| Indibano eManzi iGranulation | 60E5, 60E15 | 2-6% |
| Iingubo zeCwecwe | 60E5, 60E15 | 0.5-5% |
| Ukukhutshwa okuLawulwayo kweMatrix | 75K100000,75K15000 | 20-55% |
Iimpawu kunye neeNzuzo:
I-HPMC inonyibiliko olubalaseleyo lwamanzi kumanzi abandayo. Iyakwazi ukuchithwa kwisisombululo esicacileyo kunye nokuvuselela okuncinci emanzini abandayo. Ngokuchasene noko, ayinyibiliki kumanzi ashushu ngaphezulu kwe-60 ℃ kwaye inokudumba kuphela. Yi-ether ye-cellulose engeyiyo ionic. Isisombululo saso asinayo i-ionic intlawulo, ayifuni ukusebenzisana neetyuwa zetsimbi okanye i-ionic organic compounds, kwaye ayihambisani nezinye izinto eziluhlaza ngexesha lenkqubo yokulungiselela; inoburhalarhume obunamandla, kwaye njengoko iqondo lokutshintshwa kwisakhiwo se-molecular sanda, lichasene kakhulu ne-allergies kwaye lizinzile; ikwayi-inert ye-metabolically. Njengomxhasi wamachiza, ayenzi i-metabolized okanye ifunnwe. Ngoko ke, ayinikezeli ukushisa kumayeza kunye nokutya. Inekhalori ephantsi, ayinatyiwa, kwaye ayinatyiwa kubantu abanesifo seswekile. Iziyobisi ze-Allergenic kunye nokutya zinokusetyenziswa okukodwa; lizinzile kwi-acids kunye ne-alkali, kodwa ukuba ixabiso le-PH lidlula i-2 ~ 11 kwaye lichaphazelekayo ngamaqondo okushisa aphezulu okanye linexesha elide lokugcina, i-viscosity yayo iya kuncipha; isisombululo sayo samanzi sinokubonelela ngomsebenzi we-Surface, ebonisa ukunyanzeliswa komphezulu ophakathi kunye namaxabiso oxinzelelo lwangaphakathi; ine-emulsification esebenzayo kwiinkqubo zesigaba sesibini, ingasetyenziselwa njenge-stabilizer esebenzayo kunye ne-colloid ekhuselayo; isisombululo sayo samanzi sineempawu ezibalaseleyo zokwenza ifilimu, kwaye ithebhulethi kunye nepilisi Isixhobo esihle sokugquma. Ukufakwa kwefilimu eyenziwe yiyo kunenzuzo yokungabi mbala kunye nokuqina. Ukongeza i-glycerin kunokuphucula iplastiki yayo.
Ukupakishwa
Ukupakishwa okusemgangathweni yi-25kg / igubu leFayibha
I-20'FCL: iitoni ezili-9 ezine-palletized; Iitoni ezili-10 ezingafakwanga iipaleti.
I-40'FCL: iitoni ezili-18 ezine-palletized; Iitoni ezingama-20 ezingafakwanga iipaleti.
Ugcino:
Yigcine kwindawo epholileyo, eyomileyo engaphantsi kwe-30 ° C kwaye ikhuselwe kumswakama kunye nokucinezela, ekubeni impahla i-thermoplastic, ixesha lokugcina akufanele lidlule kwiinyanga ezingama-36.
Amanqaku okhuseleko:
Le datha ingentla ihambelana nolwazi lwethu, kodwa musa ukukhulula abathengi ngokuyijonga ngononophelo yonke ngokukhawuleza xa uyifumene. Ukunqanda ukwakheka okwahlukileyo kunye nemathiriyeli ekrwada eyahlukeneyo, nceda wenze uvavanyo olungakumbi phambi kokuba uyisebenzise.
Ixesha lokuposa: Nov-26-2023