IHydroxypropyl methylcellulose (HPMC) yipolymer eguquguqukayo esetyenziswa kakhulu kumashishini ahlukeneyo abandakanya amayeza, ukutya kunye nokwakha. Enye yeempawu zayo eziphambili kukugcinwa kwamanzi, okudlala indima ebalulekileyo ekunqumeni ukusebenza kwayo kwizicelo ezahlukeneyo.
1. Intshayelelo:
IHydroxypropylmethylcellulose (HPMC) yi-cellulose-based polymer ephuma kwi-cellulose yendalo. Iye yatsala ingqalelo kubuchule bayo obugqwesileyo bokwenza ifilimu, iipropathi zokuncamathelisa kwaye, okona kubaluleke kakhulu, iipropati zokugcina amanzi. Umthamo wokubamba amanzi we-HPMC yiparameter ebalulekileyo kwizicelo ezifana nemathiriyeli yokwakha, ukwakhiwa kwamayeza, kunye neemveliso zokutya.
2. Ukubaluleka kokugcinwa kwamanzi kwi-HPMC:
Ukuqonda iipropati zokugcina amanzi ze-HPMC kubalulekile ekuphuculeni ukusebenza kwayo kwizicelo ezahlukeneyo. Kwizinto zokwakha, iqinisekisa ukubambelela ngokufanelekileyo kunye nokusebenza kwee-mortars kunye neeplaster. Kumachiza, kuchaphazela iiprofayili zokukhutshwa kwechiza, kwaye ekutyeni, kuchaphazela ukuthungwa kunye nobomi beshelufu.
3. Izinto ezichaphazela ugcino lwamanzi:
Izinto ezininzi ezichaphazela amandla okugcina amanzi e-HPMC, kubandakanywa ubunzima bemolekyuli, iqondo lokutshintshela, ubushushu kunye noxinzelelo. Ukuqonda le miba kubalulekile ukuyila imifuniselo ebonisa ngokuchanekileyo iimeko zehlabathi lokwenyani.
4. Iindlela eziqhelekileyo zokuvavanya ugcino lwamanzi:
Indlela yeGravimetric:
Viyisha iisampulu zeHPMC phambi nasemva kokuntywiliselwa emanzini.
Bala umthamo wogcino lwamanzi usebenzisa le fomula ilandelayo: Izinga lokugcinwa kwamanzi (%) = [(Ubunzima emva kokufunxwa - Ubunzima bokuqala) / Ubunzima bokuqala] x 100.
Isalathisi sokudumba:
Ukunyuka komthamo we-HPMC emva kokuntywiliselwa emanzini kuye kwalinganiswa.
Isalathisi sokudumba (%) = [(umthamo emva kokuntywiliselwa - umthamo wokuqala)/umthamo wokuqala] x 100.
Indlela ye-Centrifugation:
Centrifuge umxube HPMC-amanzi kunye nokulinganisa umthamo wamanzi agciniweyo.
Izinga logcino lwamanzi (%) = (umthamo wokugcina amanzi / umthamo wokuqala wamanzi) x 100.
INyukliya yeMagnetic Resonance (NMR):
Intsebenziswano phakathi kwe-HPMC kunye neemolekyuli zamanzi zaphononongwa kusetyenziswa i-NMR spectroscopy.
Fumana ingqiqo kwiinguqu zenqanaba lemolekyuli kwi-HPMC ngexesha lokuthatha amanzi.
5. Amanyathelo ovavanyo:
Ukulungiselela Isampulu:
Qinisekisa ukuba iisampulu zeHPMC zimele isicelo esicetywayo.
Izinto ezilawulayo ezifana nobungakanani bamasuntswana kunye nomxholo wokufuma.
Uvavanyo lobunzima:
Ngokuchanekileyo ukulinganisa isampuli ye-HPMC elinganisiweyo.
Gxininisa isampuli emanzini ixesha elichaziweyo.
Isampuli yomisiwe kwaye ubunzima bulinganiswe kwakhona.
Bala ukugcinwa kwamanzi.
Ukwandiswa komlinganiselo wesalathiso:
Ukulinganisa umthamo wokuqala we-HPMC.
Gxila isampuli emanzini kwaye ulinganise umthamo wokugqibela.
Bala isalathisi sokwandiswa.
Uvavanyo lwe-Centrifuge:
Xuba HPMC ngamanzi kwaye uvumele ukulingana.
I-Centrifuge umxube kwaye ulinganise umthamo wamanzi agciniweyo.
Bala ukugcinwa kwamanzi.
Uhlalutyo lwe-NMR:
Ukulungiswa kweesampuli zamanzi ze-HPMC zohlalutyo lwe-NMR.
Hlalutya utshintsho kwiikhemikhali zokutshintsha kunye nokuqina kwencopho.
Ukunxulumanisa idatha ye-NMR kunye neempawu zokugcina amanzi.
6. Uhlalutyo lwedatha kunye nokutolikwa:
Cacisa iziphumo ezifunyenwe ngendlela nganye, ngokuqwalasela iimfuno ezithile zesicelo. Thelekisa idatha kwiindlela ezahlukeneyo ukuze ufumane ukuqonda okubanzi kokuziphatha kokugcinwa kwamanzi kwe-HPMC.
7. Imingeni kunye neengqwalasela:
Xoxa ngemingeni enokubakho ekuvavanyeni ukugcinwa kwamanzi, njengokuguquguquka kwiisampulu ze-HPMC, iimeko zokusingqongileyo, kunye nesidingo somgangatho.
8. Isiphelo:
Iziphumo eziphambili zishwankathelwa kwaye ukubaluleka kokuqonda iimpawu zokugcina amanzi ze-HPMC kwisicelo sayo esiyimpumelelo kumashishini ahlukeneyo kugxininiswe.
9. Amathemba ekamva:
Ukuqhubela phambili okunokwenzeka kwiindlela zovavanyo kunye nobuchule kuxoxiwe ngazo ukonyusa ukuqonda kwethu kwiipropathi zogcino lwamanzi ze-HPMC.
Ixesha lokuposa: Dec-11-2023