Focus on Cellulose ethers

Wazi kangakanani ngeHydroxypropyl methyl cellulose?

Wazi kangakanani ngeHydroxypropyl methyl cellulose?

IHydroxypropyl methylcellulose (HPMC) yi-ether ye-cellulose ephuma kwi-cellulose yendalo. Yipolymer eyenziweyo, enyibilikayo emanzini, engeyiyo ionic esetyenziswa rhoqo kumashishini ahlukeneyo afana nokwakha, amayeza, ukutya, izinto zokuthambisa, kunye namalaphu.

I-HPMC iveliswa ngokuguqula iikhemikhali zeselulosi ngepropylene oxide kunye nemethyl chloride ukwazisa amaqela e-hydroxypropyl kunye ne-methyl kwimolekyuli yeselulosi. Iqondo lokutshintshwa (DS) lwe-HPMC libhekiselele kwinani le-hydroxypropyl kunye namaqela e-methyl ngeyunithi ye-anhydroglucose (AGU) yeselulosi.

I-HPMC ineempawu ezininzi ezenza kube luncedo kwizicelo ezahlukeneyo. I-soluble emanzini, yenza isisombululo esicacileyo, kwaye inozinzo oluhle lwe-thermal. Kwakhona izinzile phantsi kweemeko eziqhelekileyo zokushisa kunye ne-pH kwaye ayiboli ngokulula. I-HPMC yi-hygroscopic, ethetha ukuba inokufunxa kwaye igcine ukufuma. Ayinatyhefu, ayicaphukisi, kwaye ayinayo i-allergenic, eyenza ikhuseleke ukusetyenziswa kwizicelo ezininzi.

Kushishino lokwakha, i-HPMC isetyenziswa njenge-thickener, binder, kunye ne-arhente yokugcina amanzi kwiimveliso ezenziwe ngesamente, izinto zokuncamathelisa iithayile, iiplates, kunye nezinye izinto zokwakha. Kwishishini lamachiza, i-HPMC isetyenziswa njenge-binder, i-disintegrant, kunye nefilimu-yangaphambili kwi-tablet kunye ne-capsule formulations. Kwishishini lokutya, i-HPMC isetyenziswa njenge-thickener, emulsifier, kunye ne-stabilizer kwiimveliso ezahlukeneyo. Kwizinto zokuthambisa, i-HPMC isetyenziswa njenge-thickener, ifilim-former, kunye ne-emulsifier kwiikhrimu, izinto zokuthambisa, kunye nolunye uqulunqo.

Lilonke, i-HPMC yipolymer eguquguqukayo kwaye eluncedo enoluhlu olubanzi lwezicelo kumashishini ahlukeneyo ngenxa yeempawu zayo ezizodwa.


Ixesha lokuposa: Mar-17-2023
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