Isitatshi seHydroxypropyl(HPS) kunyeI-Hydroxypropyl methyl cellulose(HPMC) ziipolysaccharides ezimbini ezisetyenziswa ngokuqhelekileyo kwizicelo ezahlukeneyo zamashishini, kubandakanywa amayeza, ukutya, kunye nokwakha. Ngaphandle kokufana kwazo, i-HPS kunye ne-HPMC inomahluko ohlukileyo kwizakhiwo zabo zomzimba kunye neekhemikhali, kunye neendima zabo zokusebenza. Kweli nqaku, siza kuphonononga umahluko phakathi kwe-HPS kunye ne-HPMC ngokwesakhiwo sabo sekhemikhali, iipropathi, kunye nokusetyenziswa.

Ulwakhiwo lweMichiza

I-HPS yincindi yesitatshi efunyanwa ngokuguqula imichiza yesitatshi sendalo ngamaqela e-hydroxypropyl. Amaqela e-hydroxypropyl aqhotyoshelwe kumaqela e-hydroxyl kwi-molecule ye-starch, okubangelwa isitashi esilungisiweyo kunye nokuphuculwa kwe-solubility kunye nokuzinza. I-HPMC, kwelinye icala, i-cellulose derivative efunyenwe ngokuguqula iikhemikhali zeselulosi kunye ne-hydroxypropyl kunye namaqela e-methyl. Amaqela e-hydroxypropyl ancanyathiselwe kumaqela e-hydroxyl kwi-molecule ye-cellulose, ngelixa amaqela e-methyl eqhotyoshelwe kwiiyunithi ze-anhydroglucose.

Iipropati

I-HPS kunye ne-HPMC zineempawu ezicacileyo zomzimba kunye neekhemikhali ezenza ukuba zilungele izicelo ezahlukeneyo. Iimpawu zeHPS ziquka:

1. I-Solubility: I-HPS iyanyibilika emanzini kwaye inokwenza izisombululo ezicacileyo kwiindawo eziphantsi.
2. I-Viscosity: I-HPS ine-viscosity ephantsi xa kuthelekiswa ne-HPMC kunye nezinye iipolysaccharides.
3. Ukuzinza: I-HPS izinzile kuluhlu olubanzi lwamaqondo okushisa kunye namanqanaba e-pH kwaye iyamelana ne-enzymes kunye nezinye izinto eziphazamisayo.
4. I-Gelation: I-HPS inokwenza iigels eziguquguqukayo ze-thermal kugxininiso oluphezulu, okwenza ukuba ilungele ukutya okuhlukahlukeneyo kunye nokusetyenziswa kwamayeza.

Iimpawu zeHPMC ziquka:

1. Ukunyibilika: I-HPMC iyanyibilika emanzini kwaye yenza izisombululo ezicacileyo kwiindawo eziphantsi.
2. I-Viscosity: I-HPMC ine-viscosity ephezulu kwaye inokwenza izisombululo ze-viscous nakwiindawo eziphantsi.
3. Ukuzinza: I-HPMC izinzile kuluhlu olubanzi lwamaqondo obushushu kunye namanqanaba e-pH kwaye ayichasananga ne-enzymes kunye nezinye ii-agent eziphazamisayo.
4. Isakhono sokwenza ifilim: I-HPMC inokwenza iifilim ezibhityileyo, ezibhetyebhetye eziluncedo kwiinkqubo ezahlukeneyo zamayeza nezokuthambisa.

Usetyenziso

I-HPS kunye ne-HPMC zinezicelo ezahlukeneyo ngenxa yeempawu zazo ezahlukileyo. Usetyenziso lweHPS lubandakanya:

1. Ukutya: I-HPS isetyenziselwa ukujiyisa nokuzinzisa kwiimveliso ezahlukahlukeneyo zokutya, njengesosi, isuphu, kunye nezinxibo.
2. Amachiza: I-HPS isetyenziswa njengesibophelelo kunye ne-disintegrant kwiipilisi kunye ne-capsules nanjengesithuthi sokuhanjiswa kweziyobisi.
3. Ulwakhiwo: I-HPS isetyenziswa njengesityebi kunye nesibophelelo kwiimveliso ezenziwe ngesamente, ezifana nodaka kunye nekhonkrithi.

Usetyenziso lwe-HPMC lubandakanya:

1. Ukutya: I-HPMC isetyenziswa njenge-thickener kunye nezinzisi kwiimveliso ezahlukeneyo zokutya, ezifana ne-ayisikrimu, iyogathi, kunye nezinto ezibhakiweyo.
2. Pharmaceutical: I-HPMC isetyenziswa njenge-binder, disintegrant, kunye ne-agent eyenza ifilimu kwiipilisi kunye ne-capsules kunye nesithuthi sokuhanjiswa kweziyobisi.
3. Ukhathalelo Lobuqu: I-HPMC isetyenziswa kwiimveliso ezahlukeneyo zokhathalelo lomntu, ezifana neloshini, iishampu, kunye nezinto zokuthambisa, njengento etyebisayo kunye nezinzisi.
4. Ulwakhiwo: I-HPMC isetyenziswa njenge-thickener kunye ne-binder kwiimveliso ezisekwe kwisamente, ezifana nodaka kunye nekonkile, kunye ne-arhente yokugquma kwizinto zokwakha.

Ukuqukumbela

Ukuqukumbela, i-HPS kunye ne-HPMC zi-polysaccharides ezimbini ezisetyenziswa ngokubanzi kwizicelo ezahlukeneyo zamashishini. I-HPS sisitatshi esiphuma kwisitatshi esine-viscosity esezantsi noko, iyakwazi ukuguqulwa ngokwe-thermal, kwaye izinzile kuluhlu olubanzi lobushushu kunye namanqanaba e-pH. I-HPMC, kwelinye icala, i-cellulose derivative ene-viscosity ephezulu, inokwenza iifilimu ezincinci, eziguquguqukayo, kwaye izinzile kuluhlu olubanzi lobushushu kunye namanqanaba e-pH. Umahluko phakathi kwezi zixhobo zimbini zibenza bafaneleke kwizicelo ezahlukeneyo kumashishini ahlukeneyo, kuquka ukutya, amayeza, ukunakekelwa komntu kunye nokwakhiwa.