introduce
Hydroxypropyl methylcellulose (HPMC) is nonionic cellulose ether inoshandiswa zvakanyanya mumaindasitiri akasiyana siyana nekuda kwehunhu hwayo hwakanaka hwakadai sekunyungudika kwemvura, kugadzira firimu, uye kunamatira. Kugona kwayo kushandura viscosity kunoita kuti ive yakanaka kune akawanda maapplication, kusanganisira chikafu, mishonga uye pendi. HPMC inotorwa kubva kune yakasikwa polymer cellulose, iyo glycosylated kuumba cellulose-oxygen network chimiro. Izvo zvivakwa uye viscosity yeHPMC zvinoenderana nezvinhu zvakaita sehuremu hwemamorekuru, dhigirii rekutsiva, kutarisisa, solvent mhando, pH, tembiricha uye ionic simba.
Muchikamu chino, tichakurukura zvinhu zvinokanganisa HPMC viscosity uye maitiro avo.
molecular uremu
Iyo molecular huremu hweHPMC inonyanya kuona viscosity yayo. Zviripachena, iyo yakakwirira iyo molecular uremu, iyo inowedzera viscous inova. Huremu hwehuremu hweHPMC hunobva pa10 ^ 3 kusvika ku10 ^ 6 Da. Sezvo huremu hwemamorekuru hunowedzera, huwandu hwekunamatira pakati peHPMC cheni hunowedzerawo, zvichikonzera kuwedzera kwe viscosity.
Degree rekutsiva
Iyo dhigirii yekutsiva (DS) yeHPMC inotarisa huwandu hwehydroxypropyl uye methyl mapoka muchimiro chayo. HPMC ine DS yepamusoro ine hydrophobic uye isinganyanyike mumvura pane HPMC ine DS yakaderera. Iyo dhigirii yekutsiva inokanganisa kunyungudika kweHPMC mumvura, izvo zvinozokanganisa kugona kwayo kuumba network dzakasungwa uye kuwedzera viscosity.
focus
Concentration ndechimwe chezvinhu zvakakosha zvinokanganisa HPMC viscosity. Kazhinji, iyo viscosity yeHPMC mhinduro inowedzera nekuwedzera kusungwa. Maitiro aya anonzi anokonzerwa nekupinzwa kwemaketani eHPMC munzvimbo dzakakwirira.
Solvent type
Mhando yekunyungudutsa inoita basa rakakosha mune viscosity yeHPMC. Mune zvimwe zviitiko, HPMC ine yakakwira viscosity mumvura kupfuura mune mamwe organic solvents. Chikonzero chinogona kunge chiri nekuda kwekudyidzana kwakasiyana pakati pe solvent neHPMC mamorekuru.
pH
Iyo pH yemhinduro inogona kukanganisa zvakanyanya viscosity yeHPMC. Pa acidic pH, HPMC inogona kuumba hydrogen zvisungo ne solvent, zvichikonzera kuwedzera kwe viscosity. Uyezve, pH inokanganisa dhigirii reionization yehydroxypropyl uye methyl mapoka, izvo zvinozokanganisa kupindirana kwemagetsi uye hydrophobic pakati peHPMC maketani.
tembiricha
Tembiricha zvakare ine mhedzisiro pane viscosity yeHPMC. Pakupisa kwepamusoro, mamorekuru eHPMC ane mafambiro epamusoro, zvichikonzera kuderedzwa kwema intermolecular. Maitiro aya anowanzo konzera kudzikira kwemhinduro viscosity. Mamiriro anopesana anoonekwa pakudziya kwakaderera. Nekuda kwekuoma kwemamorekuru eHPMC, viscosity yemhinduro inowedzera nekudzikira tembiricha.
ionic simba
Ionic simba chimwe chinhu chinokanganisa HPMC viscosity. Iyi parameter inoreva kusangana kweiyoni mumushonga. Minyu yakaita sesodium chloride inogona kukanganisa zvakanyanya viscosity yeHPMC nekuita shanduko mune ionization mamiriro ehydroxypropyl uye methyl mapoka. Shanduko iyi inoshandura kudyidzana pakati peHPMC mamorekuru, nekudaro kukanganisa viscosity yemhinduro.
mukupedzisa
Iyo viscosity yeHPMC inobatwa nezvinhu zvakawanda, zvinosanganisira huremu hwemamorekuru, dhigirii rekutsinhanisa, concentration, solvent type, pH, tembiricha uye ionic simba. Paunenge uchigadzira zvigadzirwa zvine HPMC, zvakakosha kuti utarise zvese izvi zvinhu kuti uve nechokwadi chekuti viscosity inodiwa inowanikwa. Kunyatsogadzirisa zvinhu izvi kunogona kukonzera kuumbwa kwechigadzirwa chinoshanda uye chakagadzikana chinosangana nechinangwa chayo.
Nguva yekutumira: Sep-12-2023