Hydroxypropylmethylcellulose (HPMC) ndechimwe chezvinhu zvinonyanya kushandiswa mumaindasitiri emishonga uye ezvekudya pamwe nemuindasitiri yekuvaka. Imwe yemabhenefiti makuru eHPMC kugona kwayo kuchengetedza mvura, izvo zvinoita kuti ive yakanaka kune akasiyana maapplication. Kuita kwekuchengetedza mvura kweHPMC kunokanganiswa nezvakawanda zvinhu, zvinosanganisira viscosity, zvirimo, ambient tembiricha uye chimiro chemolecular.
viscosity
Chimwe chezvikonzero zvikuru zvinokanganisa kuchengetedzwa kwemvura kweHPMC ndiko viscosity yayo. Viscosity zvinoreva ukobvu kana kuramba kuyerera kwechinhu. Kune HPMC, iyo yakakwirira viscosity, iyo yakakwirira yekuchengetedza mvura.
Yepamusoro viscosity HPMC ine yakakwira molecular uremu, zvinoreva kureba polymer cheni. Maketani akareba anoita kuti zviome kuti mamorekuru emvura afambe nepakati pezvinhu. Izvi zvinoguma nekuchengetedza kwepamusoro kwemvura sezvo mamorekuru emvura akavharirwa mukati mepolymer matrix, iyo inowedzera simba rose rematrix.
content
Chimwe chinhu chinokanganisa mashandiro ekuchengetedza mvura kweHPMC ndezvemukati. HPMC ine zvikamu zviviri zvikuru zvine mwero wakasiyana wehydrophilicity, zvinoti methoxyl nehydroxypropyl. Iyo yakakwira iyo hydroxypropyl yemukati muHPMC, inova huru yekugona kuchengetedza mvura.
Iro hydroxypropyl boka muHPMC rinotarisa maitiro ekuchengetedza mvura. Aya mapoka anokwezva nekuchengetedza mamorekuru emvura, zvichiita kuti HPMC iwedzere. Kuzvimba uku kunobatsira kugadzira chipingamupinyi chinononotsa kubuda kwemvura kubva kuHPMC. Mapoka eMethoxy, kune rumwe rutivi, haasi se hydrophilic semapoka e-hydroxypropyl uye nokudaro haabatsiri zvakanyanya pakuchengetedza mvura.
ambient tembiricha
Ambient tembiricha chimwe chinhu chinokanganisa mashandiro ekuchengetedza mvura kweHPMC. Sezvo tembiricha inowedzera, simba rekuchengetedza mvura reHPMC rinodzikira. Izvi zvinoitika nekuti pakupisa kwepamusoro, cheni dzepolymer dzeHPMC dzine simba rakawanda rekinetic, uye dzinofamba nekukurumidza. Nekuda kweizvozvo, mamorekuru emvura anoburitswa nekukurumidza kubva kune polymer matrix. Zvakare, pakudzikira tembiricha, mamorekuru emvura anowedzera kusimba muHPMC matrix, zvichikonzera kuchengetwa kwemvura kwakakwira.
Naizvozvo, zvakakosha kudzora ambient tembiricha panguva yekugadzira maitiro kuti ive nechokwadi chakafanana uye chakavimbika chekuchengetedza mvura kuita.
Molecular Structure
Iyo mvura yekuchengetedza simba yeHPMC inokanganiswawo neiyo mamorekuru chimiro. Iyo molecular chimiro cheHPMC inotarwa nedhigirii rekutsiviwa (DS) uye molecular uremu kugovera.
Iyo dhigirii yekutsiva inoreva kune iyo iyo hydroxyl mapoka e cellulose anotsiviwa nemapoka ehydroxypropyl. HPMC ine dhigirii repamusoro rekutsiva ine yakakwirira yekuchengeta mvura. Kusiyana neizvi, HPMC ine yakaderera dhigirii yekutsiva ine yakaderera yekuchengeta mvura.
Iyo molecular huremu kugovera kweHPMC inokanganisawo simba rekuchengetedza mvura. Kukwirisa huremu hwemamorekuru, ndiko kunowedzera simba rekuchengetedza mvura, sezvo mamorekuru akakura achigadzira chimiro chematrix chakasimba chinobata mamorekuru emvura zvakanyanya.
mukupedzisa
HPMC chinhu chinobatsira kwazvo nekuda kwekunaka kwayo kuchengetedza mvura. Iyo yekuchengeta mvura yeHPMC yakanangana neiyo viscosity, zvirimo, ambient tembiricha uye chimiro chemolecular. Naizvozvo, kusarudza iyo chaiyo HPMC kune chaiyo application inoda kunyatsotarisisa zvinhu izvi. Pakazere, HPMC inokanganisa kunaka uye kugona kwezvakasiyana zvigadzirwa mumaindasitiri akati wandei, kusanganisira zvemishonga, chikafu, uye kuvaka.
Nguva yekutumira: Aug-30-2023