Hydroxypropylmethylcellulose (HPMC) chinhu chinowanzo shandiswa mukuwedzera mune zvemishonga, chikafu uye kuvaka maindasitiri. Ihupfu husina ruvara, husinganhuhwi hunonyunguduka mumvura kuita gel gobvu-rakafanana nemagadzirirwo. HPMC, inozivikanwawo se hypromellose, inotorwa kubva kune yakasikwa cellulose. Iyo yakachengeteka, isiri-chepfu, biodegradable komboni ine huwandu hwakawanda hwekushandisa.
Basa reHPMC muindasitiri yemishonga rinonyanya kunge binder, thickener uye solubilizer mukugadzira mapiritsi. Inobatsira kuvandudza tablet yemuviri zvinhu nekupa chimiro chakafanana, kuvandudza compressibility uye kudzivirira kuparadzaniswa kwechinhu chinoshanda. HPMC inoshandiswawo seyekuputira mune yakawedzera-kuburitsa piritsi maumbirwo kubatsira kuburitsa inoshanda zvinongedzo nenzira inodzorwa nekufamba kwenguva.
Muindasitiri yechikafu, HPMC inoshandiswa seyakakora, stabilizer uye emulsifier mukudya kwakasiyana siyana. Inobatsira kuvandudza magadzirirwo, kutaridzika uye hupenyu hwesherufu hwezvikafu zvakaita seaizikirimu, sosi uye zvigadzirwa zvekubheka. HPMC inoshandiswawo sechinzvimbo chemafuta nemafuta mune yakaderera-mafuta, yakaderera-calori chikafu.
Muindasitiri yekuvaka, HPMC inoshandiswa seyakakora, inochengetedza mvura uye inosungira mukugadzira zvigadzirwa zvesimende. Inobatsira kuvandudza kushanda, simba uye kusimba kwemasanganiswa esimende uye inodzivirira kutsemuka kubva pakuumbwa. HPMC inoshandiswawo mukugadzira gypsum uye putty sechinhu chinosunga.
Basa reHPMC mumaindasitiri ari pamusoro rakakosha uye harigone kufuratirwa. Kushandiswa kweHPMC mumishonga kunovimbisa kuti dosing yakarurama uye isingachinji, inobatsira kuvandudza bioavailability yezvishandiso zvinoshanda, uye inoita kuti mishonga inakidze. Kushandisa HPMC mune zvigadzirwa zvechikafu kunovimbisa kuenderana magadzirirwo, kutaridzika uye kuravira, ukuwo uchiwedzera hupenyu hwesherufu hwechikafu. Kushandiswa kweHPMC mukuvaka kunovimbisa kushanda kwakaringana kwemasanganiswa esimende, zvichikonzera zvivakwa zvakasimba uye zvakasimba.
Pamusoro pezvivakwa zvayo zvinoshanda, HPMC inobatsirawo kune zvakatipoteredza. Kusiyana nezvimwe zvekuwedzera zvekugadzira, inoodza uye haina njodzi kune zvakatipoteredza. HPMC haina chepfu uye yakachengeteka kuti ishandiswe nevanhu, zvichiita kuti ive sarudzo yakakurumbira muchikafu nemishonga.
Mukupedzisa, kushandiswa kweHPMC mumaindasitiri akasiyana kune mhedzisiro yakanaka pakuita kwechigadzirwa uye kushamwaridzana kwezvakatipoteredza. Yakaratidza kushanda mumishonga sebinder, thickener uye solubilizer, muzvokudya semukobvu, stabilizer uye emulsifier, uye mukuvaka sechinhu chinochengetedza mvura. HPMC yakachengeteka, isiri-chepfu musanganiswa iyo inoodza, ichiita sarudzo yakanaka kune aya maindasitiri. Naizvozvo, maindasitiri akasiyana anofanira kukurudzirwa kushandisa HPMC kuti ive nani.
Nguva yekutumira: Jul-18-2023