Mhedzisiro yeHydroxypropyl Methyl Cellulose HPMC pane Kugadzika Nguva yeKongiri.

Nguva yekugadzika kongiri inonyanya kuenderana nekugadzika nguva yesamende, uye pesvedzero yeaggregate haisi huru. Naizvozvo, mhedzisiro yehydroxypropyl methylcellulose HPMC panguva yekumisikidza yepasi pemvura isiri-dispersible kongiri musanganiswa inogona kudzidzwa kuburikidza nekuisa nguva yedhaka. Sezvo nguva yekugadzika kwedhaka inobatwa nemvura, kuitira kuti uongorore mhedzisiro yeHPMC panguva yekugadzika kwedhaka, chiyero chemvura-samende uye dhaka redhaka rinoda kugadziriswa.

Mhedzisiro yekuedza inoratidza kuti kuwedzerwa kwehydroxypropyl methylcellulose HPMC kune zvakakosha kudzoreredza pamusanganiswa wedhaka, uye nguva yekugadzika yedhaka inorebeswa nekuwedzera kwehuwandu hwehydroxypropyl methylcellulose. Panyaya yezvakafanana zveHPMC, dhaka rakaumbwa pasi pemvura riri nani pane dhaka rakaumbwa mumhepo. Kuumbwa kwepakati kunotora nguva yakareba kuti kusete. Kana yakayerwa mumvura, kana ichienzaniswa nemuenzaniso usina chinhu, nguva yekutanga yekugadzika yedhaka yakasanganiswa nehydroxypropyl methylcellulose yakanonoka nemaawa 6-18, uye nguva yekupedzisira yekuisa yakanonoka nemaawa 6-22. Naizvozvo, HPMC inofanirwa kushandiswa pamwe chete nevamiriri vesimba rekutanga.

HPMC ndeyepamusoro molecular polymer ine macromolecular linear chimiro. Boka rayo rinoshanda rine mapoka e-hydroxyl, anogona kuumba hydrogen zvisungo nemamorekuru emvura akasanganiswa uye kuwedzera viscosity yemvura yakasanganiswa. Iyo yakareba mashetani echeni eHPMC inokwezva mumwe nemumwe, ichiita HPMC mamorekuru akabatanidzwa kuti aumbe network chimiro, kuputira simende uye kusanganisa mvura. Sezvo HPMC ichigadzira firimu-rakafanana netiweki chimiro chekuputira simende, inogona kudzivirira kuvhurika kwemvura mudhaka, uye kutadzisa kana kudzikamisa hydration rate yesimende.