Iyo alkaline immersion yekugadzira nzira inzira yakajairika yekugadzira hydroxypropyl methyl cellulose (HPMC). Iyi nzira inosanganisira kuita kwe cellulose ine sodium hydroxide (NaOH) uyezve nepropylene oxide (PO) uye methyl chloride (MC) mune mamwe mamiriro.
Iyo alkaline kunyudza nzira ine mukana wekugadzira HPMC ine yakakwira dhigirii yekutsiva (DS), iyo inosarudza zvimiro zvayo senge solubility, viscosity, uye gelation. Iyo nzira inosanganisira matanho anotevera:
- Kugadzirira kweCellulose
Cellulose inowanikwa kubva kune zvakasikwa sehuni, donje, kana zvimwe zvinomera. Iyo cellulose inotanga kucheneswa uye yozobatwa neNaOH kuti igadzire sodium cellulose, inova reactive repakati mukugadzirwa kweHPMC.
- Kuita kweSodium Cellulose nePropylene Oxide (PO)
Iyo sodium cellulose inobva yaitwa nePO muhupo hwechigadziro chakadai se tetramethylammonium hydroxide (TMAH) kana sodium hydroxide (NaOH) pakupisa kwakanyanya uye kudzvinyirira. Kuita kunoguma nekuumbwa kwehydroxypropyl cellulose (HPC).
- Kuita kweHPC neMethyl Chloride (MC)
HPC inobva yaitwa pamwe neMC pamberi pekatalyst yakadai sodium hydroxide (NaOH) kana hydrochloric acid (HCl). Kuita kunoguma nekuumbwa kwehydroxypropyl methyl cellulose (HPMC).
- Kuwacha nekuomesa
Mushure mekuita, chigadzirwa chinoshambidzwa nemvura uye chakaomeswa kuwana HPMC. Chigadzirwa chacho chinowanzocheneswa uchishandisa zvakatevedzana zvefiltration uye centrifugation matanho ekubvisa chero tsvina.
Iyo alkaline kunyudza nzira ine zvakati wandei pane dzimwe nzira, kusanganisira yakakwira DS uye kuchena, mutengo wakaderera, uye nyore scalability. Iyo nzira inogona zvakare kushandiswa kugadzira HPMC ine akasiyana zvivakwa nekusiyanisa maitiro ekuita senge tembiricha, kudzvanywa, uye kuisa pfungwa.
Zvisinei, nzira yacho inewo zvimwe zvipingamupinyi. Kushandiswa kweNaOH uye MC kunogona kuisa kuchengeteka uye njodzi dzezvakatipoteredza, uye nzira yekugadzira inogona kutora nguva yakawanda uye inoda simba guru.
Mukupedzisa, iyo alkaline kunyudza nzira yekugadzira inzira inoshandiswa zvakanyanya kugadzira HPMC. Iyo nzira inosanganisira kuita kweselulosi neNaOH, PO, uye MC pasi pemamwe mamiriro, inoteverwa nekucheneswa nekuomeswa. Kunyange iyo nzira ine zvimwe zvipingamupinyi, zvakanakira zvayo zvinoita kuti ive sarudzo yakakurumbira yemaindasitiri nemishonga yekushandisa.
Nguva yekutumira: Kubvumbi-23-2023