Kutsunga Kwakareruka Kwemhando yeHydroxypropyl MethylCellulose

Hydroxypropyl Methylcellulose (HPMC) inowanzoshandiswa polima muindasitiri yemishonga semubatsiri kana sechinhu chinoputira mahwendefa nemakapisi. Hunhu hweHPMC hunogona kutariswa neakasiyana paramita, senge viscosity, hunyoro hwemukati, particle size distribution, uye kuchena.

Imwe nzira iri nyore yekuona kunaka kweHPMC ndeyekuyera viscosity yayo. Viscosity chiyero chekuramba kwemvura kuyerera, uye yakanangana nehuremu hwemamorekuru eHPMC. Yepamusoro molecular uremu HPMC achava yakakwirira viscosity pane yakaderera molecular uremu HPMC. Naizvozvo, iyo yakakwira viscosity yeHPMC, inowedzera kunaka kwayo.

Imwe parameter yakakosha yekufunga nezve mwando weHPMC. Kuwanda kwehunyoro hwehunyoro hunogona kukonzera kuderedzwa kweHPMC, izvo zvinogona kuderedza kushanda kwayo. Huwandu hunogamuchirika hwehunyoro hweHPMC hunosiyana zvichienderana nekushandiswa kwaunoda, asi kazhinji hunofanirwa kunge huri pasi pe7%.

Iyo particle size kugovera kweHPMC zvakare chinhu chakakosha pakuona kunaka kwayo. HPMC ine yakatetepa saizi yekugovera inosarudzwa nekuti inobvumira kune inowirirana uye yakafanana chigadzirwa. Iyo particle size yekugovera inogona kutsanangurwa uchishandisa akasiyana matekiniki akadai selaser diffraction kana microscopy.

Chekupedzisira, kuchena kweHPMC kunofanirwawo kuongororwa. Kuchena kweHPMC kunogona kutariswa nekuongorora kuumbwa kwayo kwemakemikari uchishandisa matekiniki akadai seyepamusoro-inoshanda liquid chromatography (HPLC) kana Fourier-shanduko infrared spectroscopy (FTIR). Kusachena muHPMC kunogona kukanganisa kuchengetedzwa kwayo uye kushanda kwayo.

Mukupedzisa, mhando yeHPMC inogona kutariswa nekuyera viscosity yayo, hunyoro hwemukati, particle size distribution, uye kuchena. Aya ma paramita anogona kuongororwa zviri nyore uchishandisa akasiyana matekiniki, uye yemhando yepamusoro HPMC inofanirwa kunge iine yakakwira viscosity, yakaderera mwando yemukati, yakatetepa saizi yekugovera, uye kuchena kwakanyanya.