Ibicuruzwa bya selile ya selile HPMC na HEMC bifite hydrophobique na hydrophilique. Itsinda rya methoxy ni hydrophobique, kandi hydroxypropoxy itsinda iratandukanye ukurikije umwanya wo gusimbuza. Bimwe ni hydrophilique nibindi ni hydrophobique. Hydroxyethoxy ni hydrophilique. Ibyo bita hydrophilicity bivuze ko ifite umutungo wo kuba hafi y'amazi; hydrophobicity bivuze ko ifite umutungo wo kwanga amazi. Kubera ko ibicuruzwa ari hydrophilique na hydrophobi, ibicuruzwa bya selile ya selile bifite ibikorwa byo hejuru, bitera umwuka mubi. Niba kimwe gusa mubintu bibiri ari hydrophilique cyangwa hydrophobique, ntagituba kizabyara. Nyamara, HEC ifite hydrophilic groupe ya hydroxyethoxy kandi ntabwo ifite hydrophobique, ntabwo rero izabyara ibibyimba.
Ibibyimba byinshi nabyo bifitanye isano itaziguye nigipimo cyo gusesa ibicuruzwa. Niba ibicuruzwa bishonga ku gipimo kidahuye, ibibyimba bizashiraho. Muri rusange, hasi yubukonje, nigipimo cyihuta. Iyo hejuru ya viscosity, gahoro gahoro. Indi mpamvu ni ikibazo cya granulation, granulation ntiringana (ingano yingingo ntisa, hariho nini na nto). Bitera igihe cyo gusesa gutandukana, bitanga umwuka mwinshi.
Ibyiza byo guhumeka ikirere birashobora kongera ubuso bwakuweho, imitungo yubwubatsi nayo iratera imbere, gutobora biroroshye, kandi gusiba ibyiciro biroroshye. Ikibi ni uko kubaho kw'ibibyimba bizagabanya ubwinshi bwibicuruzwa, bigabanye imbaraga, kandi bigira ingaruka ku guhangana n’ibihe.
Igihe cyo kohereza: Gashyantare-27-2023