HPMC (Hydroxypropyl Methyl Cellulose) ni igiti gikoreshwa cyane mugutegura. Nibikoresho bya polymer bifatanye neza, bihamye, gukora firime no kubyimba, kandi bikoreshwa cyane mubikorwa bya farumasi, ibiryo, ubwubatsi ninganda.
1. Imiterere yimiti nibintu shingiro bya HPMC
HPMC iboneka methylation igice na hydroxypropylation ya selile naturel. Itsinda rya hydroxyl (-OH) muburyo bwa molekile ryayo risimburwa igice nitsinda ryimikorere (-OCH3) cyangwa itsinda rya hydroxypropyl (-CH2CHOHCH3). Ubu buryo bwo guhindura butanga HPMC amazi meza kandi meza. By'umwihariko, HPMC irashobora gushonga vuba mumazi akonje kugirango ibe igisubizo gihamye cya colloidal, gifite ububobere bwiza no gufatira mumuti wamazi. Byongeye kandi, umubare munini wamatsinda ya hydrophilique akubiye mumiterere ya molekuline ya HPMC ituma ishobora kugumana imiterere myiza yo gufatira hamwe ahantu h’ubushuhe buhebuje, ari naryo shingiro ryingenzi ryo kuyikoresha neza muburyo butandukanye.
2. Ibyiza bya HPMC
Imikorere myiza yo gufatira hamwe
HPMC ifite imikorere myiza yo gufatira hamwe kandi irashobora gukora igicucu cyinshi kandi gihamye hejuru yibikoresho. Kwizirika kwayo biva muri hydrogène ihuza molekile n'imiterere y'urunigi rwa selile. Bikunze gukoreshwa nkibifata mubinini mu nganda zimiti kugirango bizamure neza ubukana nibihamye byibinini.
Umutungo wo gukora firime
HPMC irashobora gukora firime imwe kandi iboneye nyuma yo gukama. Iyi firime ntabwo ifite imbaraga zubukanishi gusa, ahubwo irashobora no kugira uruhare runini rwamazi cyangwa inzitizi mubintu bimwe na bimwe. Mu bikoresho byubwubatsi ninganda, HPMC ikoreshwa nkibikoresho byo kurinda no kurimbisha.
Amazi meza no kubyimba
HPMC ifite amazi meza cyane kandi irashobora gushonga vuba mumazi akonje mugihe ikora igisubizo kiboneye. Mu gutegura ibiryo, HPMC irashobora gukoreshwa nkibyimbye na stabilisateur kugirango itezimbere uburyohe nibiryo byibicuruzwa. Umubyimba wacyo wanakoreshejwe cyane muburyo bwo kwisiga, kwisiga, hamwe namazi ashingiye kumazi, bishobora guteza imbere sisitemu yo gukora.
Umutekano n'umutekano
Imiterere yimiti ya HPMC irahagaze neza, irwanya aside, alkali numunyu, kandi irashobora kugumana ububobere bwayo kandi itajegajega mugice kinini cya pH. Kubera ko HPMC ubwayo ari selile ikomoka kuri selile, mubisanzwe ntabwo ari uburozi kandi ntabwo izanduza ibidukikije, bityo rero nikintu kibisi kandi cyangiza ibidukikije.
3. Porogaramu yihariye ya HPMC mubisobanuro
Gusaba mu nganda zimiti
Mu miti ya farumasi, HPMC ikoreshwa cyane nka tablet binder, igenzurwa nogusohora hamwe na firime yahoze. Bitewe n’amazi meza cyane yo gukemura no gukora firime, HPMC ntishobora gusa kunoza imiterere yimiterere yibinini kandi igabanya igihe cyo gusenyuka ibiyobyabwenge, ariko kandi ikoreshwa mugutwikira ibiyobyabwenge, kongera igihe cyo gusohora ibiyobyabwenge mumubiri, kandi bigatera imbere igihe cyo gufata ibiyobyabwenge. Mubyongeyeho, HPMC irashobora kandi gukoreshwa nkibikoresho byo gukora firime ya capsules yoroshye, hamwe na biocompatibilité nziza kandi itajegajega.
Gusaba mubikorwa byubwubatsi
HPMC ni ibisanzwe bikoreshwa mu gufatisha no kubyimba mu nganda zubaka, kandi bikoreshwa cyane mu bikoresho bishingiye kuri sima, ibifata amatafari, ifu ya putty nibindi bisobanuro. HPMC irashobora kunoza imikorere yibikoresho byubwubatsi, kongera amazi no gusiga amavuta yo kubaka, bityo bigatuma imikorere ikora ningaruka mugihe cyubwubatsi. Mu bikoresho bishingiye kuri sima, kongeramo HPMC bifasha kugabanya gutakaza amazi, kongera igihe cyo kumisha sima, no kwirinda gucika mugihe cyo kubaka. Byongeye kandi, HPMC irashobora kandi kongera imbaraga zo gufatira kumatafari, kwemeza ko amabati akomeye kandi ntibyoroshye kugwa mugihe cyo kuyashyiraho.
Gusaba mu nganda zibiribwa
Mu nganda z’ibiribwa, HPMC, nk'ibiti byo mu rwego rwo kurya no kubyibuha, akenshi bikoreshwa mu gutegura ibiryo nk'umugati, imigati, ice cream, n'ibinyobwa. HPMC ntishobora gusa kunoza imiterere nuburyohe bwibiryo, ariko kandi irashobora kuzamura neza ubuzima bwibiryo. Mu biribwa bimwe na bimwe bidafite gluten, HPMC ikoreshwa mu gusimbuza poroteyine ya gluten, guha ibiryo imiterere myiza na elastique, no kunoza ingaruka zo guteka. Byongeye kandi, HPMC irashobora kandi gukoreshwa nka stabilisateur mugukora ice cream kugirango wirinde ko habaho kristu ya ice kandi bigatuma ice cream irushaho kuba nziza.
Gukoresha kwisiga hamwe nu miti ya buri munsi
HPMC ikoreshwa cyane mu kwisiga no kwisiga imiti ya buri munsi nkibicuruzwa byita ku ruhu, shampo, hamwe nogukoresha ibikoresho. Kwiyongera kwayo no gutuza bituma iba emulisiferi nziza kandi ihagarika ibintu, bishobora guteza imbere imiterere yimiterere nibicuruzwa. Mu bicuruzwa byita ku ruhu, HPMC irashobora gutanga firime ikingira uruhu kugirango irinde gutakaza amazi no kongera ingaruka nziza. Mubyuma, HPMC irashobora kongera ubwiza bwibicuruzwa no kunoza uburambe bwabakoresha.
4. Intsinzi yimikorere yimikorere ya HPMC
Imanza zatsinzwe mubikorwa bya farumasi: ibinini bisohora
Iyo utegura ibinini bisohora-bikomeza, uruganda rukora imiti rwakoresheje imiti igenzura-irekura HPMC kandi yongeraho urugero rwa HPMC kuri tableti kugirango igenzure neza igipimo cy’imiti irekurwa mu mubiri, bityo igere ku ntego y’igihe kirekire. kurekurwa. Gukora firime no gushikama kwa HPMC bituma irekurwa rimwe ryibiyobyabwenge ahantu ha gastrointestinal, bizamura cyane uburambe bwubuvuzi bwumurwayi.
Imanza zatsinzwe mubikorwa byubwubatsi: amatafari
Mugutegura amatafari ya tile, uruganda rukora ibikoresho byubwubatsi rwateje imbere neza ibicuruzwa bifatika hamwe na anti-slip ukoresheje HPMC. Mu bushyuhe bwinshi n’ibidukikije, HPMC muri iyi formula irashobora kwemeza ko amabati akomeye kandi atanyerera, bikazamura cyane umutekano n’ubwubatsi.
Imanza zatsinzwe mubikorwa byibiribwa: umugati udafite gluten
Isosiyete ikora ibiryo yazamuye neza uburyohe nuburyohe bwumugati yinjiza HPMC mumata yimigati idafite gluten, bituma igereranywa nimiterere yimigati gakondo irimo gluten, kandi yamamaye kumasoko. HPMC ifata neza hamwe no kubika amazi bituma umutsima utagira gluten ukora imiterere myiza ya pore mugihe cyo guteka, kunoza isura nuburyohe bwibicuruzwa.
Nkibikoresho bifatika cyane, HPMC yerekanye imikorere yayo myiza mugushinga inganda nyinshi. Hamwe na adhesion nziza cyane, imiterere ya firime, gukemura amazi no gutuza, HPMC ntishobora kuzamura ubwiza bwibicuruzwa gusa, ahubwo inatezimbere cyane mubikorwa byumusaruro hamwe nuburambe bwabakoresha. Hamwe nogukomeza gutera imbere kwikoranabuhanga, ubushobozi bwa HPMC mubikorwa byinshi bishya nabwo burimo gushakishwa, kandi biteganijwe ko buzagira uruhare runini munganda nyinshi mugihe kizaza.
Igihe cyo kohereza: Nzeri-30-2024