Hydroxypropyl methyl selulose (HPMC) ni polymer itandukanye ikoreshwa cyane mubikorwa bitandukanye, harimo ibiryo, imiti, nubwubatsi. Nibice bya sintetike ikomoka kuri selile, ni polymer karemano iboneka murukuta rwibimera. HPMC ikorwa muburyo bwo guhindura selile hamwe na hydroxypropyl hamwe na methyl matsinda, biteza imbere amazi, ubwiza, nibindi bintu. Muri iki kiganiro, tuzaganira ku miterere ya HPMC n’imikorere yayo mu nganda zitandukanye.

Amazi meza

Imwe mu miterere yingenzi ya HPMC nubushobozi bwayo bwamazi. HPMC ishonga byoroshye mumazi kugirango ikore igisubizo gisobanutse neza. Urwego rwo gukemura rushingiye ku rwego rwo gusimbuza (DS) rwa HPMC. DS bivuga umubare wa hydroxypropyl na methyl matsinda yongewe kuri buri molekile ya selile. Iyo DS iri hejuru, niko amazi menshi-HPMC ari. HPMC ifite DS ya 1.8 cyangwa irenga ifatwa nkamazi menshi.

Viscosity

Undi mutungo wingenzi wa HPMC nubukonje bwawo. HPMC ni polymer igaragara cyane, bivuze ko ifite umubyimba mwinshi, sirupi. Ubwiza bwa HPMC buterwa nibintu byinshi, harimo DS, uburemere bwa molekile, hamwe na polymer yibisubizo. Uburebure bwa DS hamwe nuburemere bwa molekuline bivamo ubwiza bwinshi. Ubukonje bwa HPMC burashobora guhinduka muguhindura ubunini bwa polymer mugisubizo.

Ubushyuhe bwumuriro

HPMC ihagaze neza kandi irashobora kwihanganira ubushyuhe bugera kuri 200 ° C nta kwangirika gukomeye. Ibi bituma bikoreshwa mugikorwa cyinganda nyinshi zirimo ubushyuhe bwinshi, nko kumisha spray no gusohora. HPMC ifite kandi imbaraga zo kurwanya aside na base, bigatuma ikoreshwa muburyo bwa acide cyangwa alkaline.

Ibyiza bya Firime

HPMC ifite ibintu byiza byerekana firime, bituma bigira akamaro mubikorwa bitandukanye. HPMC irashobora gukora firime ikomeye, yoroheje irwanya ubushuhe, ubushyuhe, nimiti. Ibi bituma bigira akamaro mu nganda zimiti yo gutwikira ibinini na capsules kugirango bigaragare neza kandi bihamye. HPMC irashobora kandi gukoreshwa mubucuruzi bwibiribwa mugukora firime ziribwa zishobora gukoreshwa mukubungabunga no kurinda ibicuruzwa byibiribwa.

Ibintu bifatika

HPMC ifite ibintu byiza bifata neza, bigira akamaro mubikorwa byubwubatsi. HPMC irashobora gukoreshwa nka binder mubicuruzwa bishingiye kuri sima, nka minisiteri na grout. Irashobora kandi gukoreshwa nkibyimbye muri tile yometse hamwe no kuzuza. HPMC itezimbere imikorere nimikorere yibi bicuruzwa itanga neza kandi ikabika amazi.

Porogaramu ya HPMC

HPMC ifite porogaramu nyinshi mu nganda zitandukanye, harimo:

Inganda zikora ibiribwa: HPMC ikoreshwa nkibyimbye, stabilisateur, na emulisiferi mubicuruzwa byinshi byibiribwa, nk'isosi, imyambarire, nibicuruzwa bitetse. Irashobora kandi gukoreshwa mugukora firime ziribwa hamwe na coatings.

Inganda zikoreshwa mu bya farumasi: HPMC ikoreshwa nkibikoresho bya tablet na capsule, kimwe noguhuza, gusenya, no kurekura-kurekura muburyo bwa farumasi.

Inganda zo kwisiga: HPMC ikoreshwa nkibyimbye na stabilisateur mubicuruzwa byinshi byo kwisiga, nk'amavuta yo kwisiga, amavuta, na shampo.

Inganda zubaka: HPMC ikoreshwa nkibikoresho bihuza, byongera umubyimba, hamwe n’amazi yo kubika amazi mu bicuruzwa bishingiye kuri sima, nka minisiteri, grout, hamwe n’ibiti byangiza.

Umwanzuro

Hydroxypropyl methyl selulose (HPMC) ni polymer itandukanye ifite ibintu byinshi byingirakamaro, harimo gushonga amazi, viscosity, stabilite yumuriro, imiterere ya firime, hamwe nibintu bifatika. HPMC ikoreshwa mu nganda zitandukanye, zirimo ibiryo, imiti, amavuta yo kwisiga, n'ubwubatsi. Ubushobozi bwayo bwo gukora firime zikomeye, zoroshye no kunoza imikorere no gukora ibicuruzwa bitandukanye bituma iba ingirakamaro mubintu byinshi. HPMC nayo ifite umutekano mukoresha mubiribwa nibicuruzwa bya farumasi kandi byemejwe ninzego zibishinzwe kwisi yose. Nkibyo, HPMC ningirakamaro kandi ikoreshwa cyane polymer igira uruhare runini mubikorwa byinshi bitandukanye.