Hypromellose yangiza umubiri?

Hypromellose, izwi kandi nka hydroxypropyl methylcellulose, ni igice cya sintetike, inert, na polymer-soluble polymer ikoreshwa cyane mu nganda zitandukanye. Bikunze gukoreshwa nkibiryo byongera ibiryo, kubyimbye, emulisiferi, kandi nkibikoresho bya farumasi mugukora ibinini, capsules, hamwe nubuvuzi bwamaso. Muri iki kiganiro, tuzasesengura umutekano wa hypromellose n'ingaruka zayo ku buzima.

Umutekano wa Hypromellose

Hypromellose muri rusange ifatwa nk’umutekano kugira ngo ikoreshwe n’inzego zinyuranye zishinzwe kugenzura, harimo n’ikigo cy’Amerika gishinzwe ibiryo n’ibiyobyabwenge (FDA), Ikigo cy’Uburayi gishinzwe umutekano w’ibiribwa (EFSA), hamwe na komite y’impuguke ihuriweho na FAO / OMS ishinzwe kongera ibiribwa (JECFA). Yashyizwe mu rwego rwa GRAS (muri rusange izwi nk’umutekano) wongeyeho ibiryo na FDA, bivuze ko ifite amateka maremare yo gukoresha neza ibiryo kandi ntibishobora guteza ingaruka iyo ikoreshejwe ku buryo busanzwe.

Muri farumasi, hypromellose ikoreshwa cyane nkibintu byizewe kandi byihanganirwa neza. Yashyizwe muri Pharmacopeia yo muri Amerika kandi ikoreshwa cyane mugukora imiterere ya dosiye ikomeye kandi yuzuye. Ikoreshwa kandi nk'amavuta yo kwisiga kandi ifatwa nkumutekano kugirango ikoreshwe mumurongo woguhuza, amarira yubukorikori, nibindi bicuruzwa byamaso.

Ubushakashatsi bwerekanye ko hypromellose ifite ubumara buke bwo mu kanwa kandi ntibwinjizwe n'umubiri. Binyura mu nzira ya gastrointestinal itavunitse, kandi isohoka mu mwanda. Hypromellose nayo ifatwa nkumutekano kugirango ikoreshwe kubagore batwite n'abonsa, kimwe nabana, nta ngaruka mbi zizwi.

Ingaruka Zubuzima Buzima bwa Hypromellose

Mugihe hypromellose isanzwe ifatwa nkumutekano mukurya, hari ingaruka zishobora kubaho kubuzima zigomba kwitabwaho.

Ingaruka zo munda

Hypromellose ni polymer-eruble polymer ikurura amazi kandi ikora ibintu bimeze nka gel iyo ihuye namazi. Ibi birashobora gutuma ubukonje bwiyongera mu nzira ya gastrointestinal, ishobora kugabanya igihe cyo gutembera kwibiryo binyuze muri sisitemu yumubiri. Ibi birashobora gutera impatwe, kubyimba, no kubura inda kubantu bamwe, cyane cyane iyo bikoreshejwe cyane.

Allergic

Allergic reaction kuri hypromellose ntisanzwe, ariko irashobora kubaho. Ibimenyetso byerekana ingaruka za allergique zishobora kuba zirimo imitiba, guhinda, kubyimba mu maso, iminwa, ururimi, cyangwa umuhogo, ingorane zo guhumeka, na anaphylaxis (reaction ikomeye, ishobora guhitana ubuzima bwa allergique). Niba uhuye na kimwe muri ibyo bimenyetso nyuma yo kurya hypromellose, hita witabaza muganga.

Kurakara Amaso

Hypromellose ikunze gukoreshwa nk'amavuta yo kwisiga mu gukora ibitonyanga by'amaso hamwe n'indi myiteguro y'amaso. Mugihe muri rusange bifatwa nkumutekano kugirango ukoreshwe mumaso, abantu bamwe bashobora kurwara amaso cyangwa izindi ngaruka mbi. Ibimenyetso byo kurakara amaso birashobora kuba bitukura, guhinda, gutwika, no kurira.

Imikoreshereze yibiyobyabwenge

Hypromellose irashobora gukorana n'imiti imwe n'imwe, cyane cyane ikenera ibidukikije bya pH bike kugirango byinjire. Ni ukubera ko hypromellose ikora ibintu bimeze nka gel iyo ihuye namazi, bishobora kugabanya umuvuduko no gusohora imiti. Niba urimo gufata imiti iyo ari yo yose, harimo imiti yandikiwe cyangwa imiti irenga imiti, ni ngombwa kugisha inama umuganga wawe mbere yo gufata hypromellose cyangwa ibindi byongera imirire.

Umwanzuro

hypromellose ifatwa nkumutekano mukoresha ninzego zinyuranye zibishinzwe. Ikoreshwa cyane nkibiryo byongera ibiryo, kubyimbye, na emulifisiyeri, hamwe nibikoresho bya farumasi mugukora ibinini, capsules, hamwe nubuvuzi bwamaso.