Hydroxypropylmethylcellulose (HPMC) ni polymer ikoreshwa cyane mubikorwa bitandukanye. Ni ether ya selile idafite ionic ether, ibora amazi, idafite uburozi kandi idatera uburakari. HPMC isanzwe ikoreshwa nkibyimbye, binder na emulisiferi mubiribwa byinshi, imiti nibicuruzwa byumuntu.
Imwe mu miterere yingenzi ya HPMC nuburemere bwayo bwa molekuline, igira ingaruka ku bwiza bwayo. Viscosity ni igipimo cyo kurwanya amazi. Iyo hejuru yubukonje, niko amazi menshi. Uburemere bwa molekuline ni igipimo cy'ubunini bwa molekile, bifitanye isano itaziguye n'ubukonje bwa HPMC.
HPMC iraboneka mubyiciro bitandukanye ukurikije uburemere bwayo. Ubukonje bwa HPMC bwiyongera hamwe nuburemere bwa molekile. Ubukonje bwa HPMC buterwa kandi n’urwego rwo gusimbuza (DS), akaba ari umubare w’amatsinda ya hydroxypropyl na methyl yometse ku mugongo wa selile. Iyo DS iri hejuru, nuburemere bwa molekuline nuburemere bwa HPMC.
Ubukonje bwa HPMC nabwo bugira ingaruka ku kwibanda kwa polymer mu gisubizo. Mugihe gito, iminyururu ya polymer iratatana kandi igisubizo cyibisubizo biri hasi. Mugihe kwibanda kwiyongera, iminyururu ya polymer itangira guhuzagurika no gufatana, bigatuma kwiyongera kwijimye. Kwibanda kumurongo wa polymer utangira guhuzagurika byitwa guhuzagurika.
Uburemere bwa molekuline hamwe nubwiza bwa HPMC nibintu byingenzi mubicuruzwa byinshi. Mu nganda zibiribwa, HPMC ikoreshwa nkibyimbye byamasosi, imyambarire nibicuruzwa bitetse. Uburemere bukwiye bwa molekuline hamwe nubwiza bwa HPMC butuma imiterere yifuzwa hamwe numunwa wibicuruzwa byanyuma.
Mu nganda zimiti, HPMC ikoreshwa nkibihuza ibinini na capsules. Uburemere bwa molekuline hamwe nubwiza bwa HPMC bigena imbaraga za tablet nubushobozi bwayo bwo gushonga mumitsi yigifu.
Mu nganda zita ku muntu ku giti cye, HPMC ikoreshwa nk'ibyimbye na emulisiferi muri shampo, amavuta yo kwisiga hamwe na cream. Uburemere bukwiye bwa molekuline hamwe nubwiza bwa HPMC byemeza neza ko bihamye kandi bihamye byibicuruzwa.
Muri make, uburemere bwa molekuline hamwe nubwiza bwa HPMC nibintu byingenzi bigira ingaruka kumikorere yabyo mubikorwa bitandukanye. Gusobanukirwa isano iri hagati yibi bipimo ningirakamaro mugutegura ibicuruzwa byujuje ibyifuzo. HPMC ni polymer itandukanye kandi ifite agaciro ifasha kuzamura ubwiza nimikorere yibicuruzwa byinshi.
Igihe cyoherejwe: Nyakanga-18-2023