Itandukaniro hagati ya HEC na EC

HEC na EC ni ubwoko bubiri bwa selile ya ether hamwe nibintu bitandukanye. HEC isobanura hydroxyethyl selulose, naho EC igereranya Ethyl selile. Muri iki kiganiro, tuzaganira ku itandukaniro riri hagati ya HEC na EC ukurikije imiterere y’imiti, imiterere, imikoreshereze, n’umutekano.

1. Imiterere yimiti

HEC na EC bifite imiterere yimiti itandukanye ibaha ibintu bitandukanye. HEC ni polymer yamashanyarazi ikomoka kuri selile. Ni selile yahinduwe ya selile ifite hydroxyethyl matsinda ifatanye numugongo wa selile. Urwego rwo gusimbuza (DS) rwa HEC bivuga umubare wamatsinda ya hydroxyethyl aboneka kuri anhydroglucose (AGU) yumugongo wa selile. DS ya HEC irashobora kuva kuri 0.1 kugeza 3.0, hamwe nibiciro bya DS byerekana urwego rwo hejuru rwo gusimburwa.

EC kurundi ruhande, ni polymer idashobora gushonga polymer nayo ikomoka kuri selile. Ni selile yahinduwe ya ether ifite amatsinda ya Ethyl afatanye numugongo wa selile. DS ya EC bivuga umubare wamatsinda ya Ethyl aboneka kuri AGU yumugongo wa selile. DS ya EC irashobora kuva kuri 1.7 kugeza kuri 2.9, hamwe nibiciro bya DS byerekana urwego rwo hejuru rwo gusimburwa.

2. Ibyiza

HEC na EC bifite imitungo itandukanye ituma ibera porogaramu zitandukanye. Bimwe mubintu byingenzi bya HEC na EC byerekanwe hano hepfo:

a. Gukemura: HEC irashonga cyane mumazi, mugihe EC idashonga mumazi. Nyamara, EC irashobora gushonga mumashanyarazi nka Ethanol, acetone, na chloroform.

b. Rheologiya: HEC ni ibikoresho byitwa pseudoplastique, bivuze ko byerekana imyitwarire yo kunanuka. Ibi bivuze ko ubwiza bwa HEC bugabanuka uko igipimo cyogosha cyiyongera. EC kurundi ruhande, ni ibikoresho bya termoplastique, bivuze ko bishobora koroshya no kubumba iyo bishyushye.

c. Ibikoresho byo gukora firime: HEC ifite imiterere myiza yo gukora firime, ituma ikoreshwa muburyo bwo kwambara no gukina film. EC ifite kandi imiterere yo gukora firime, ariko firime zirashobora kuba zoroshye kandi zikunda gucika.

d. Igihagararo: HEC ihagaze neza mugice kinini cya pH nubushyuhe. EC nayo irahagaze hejuru ya pH yagutse, ariko ituze ryayo irashobora guterwa nubushyuhe bwo hejuru.

3. Gukoresha

HEC na EC bikoreshwa muburyo butandukanye mubisabwa mubiribwa, imiti, ninganda zita kubantu. Bimwe mubyingenzi bikoreshwa bya HEC na EC byerekanwe hano hepfo:

a. Inganda zibiribwa: HEC ikoreshwa cyane mubyimbye, stabilisateur, na emulisiferi mubicuruzwa byibiribwa nka sosi, imyambarire, nibicuruzwa bitetse. EC ikoreshwa nkibikoresho byo gutwika ibiryo nka chewine, ibiryo, n'ibinini.

b. Inganda zikoreshwa mu bya farumasi: HEC ikoreshwa nkibikoresho, bidahuza, hamwe na tableti yububiko bwa farumasi. EC ikoreshwa nka binder, coating agent, hamwe na agent-irekura-irekura imiti.

4. Umutekano

HEC na EC mubisanzwe bifatwa nkumutekano mukoresha mubiribwa no gukoresha imiti. Ariko, kimwe nibintu byose bya shimi, hashobora kubaho ingaruka zijyanye no gukoresha. Ni ngombwa gukurikiza amabwiriza asabwa yo gukoresha HEC na EC kugirango barebe ko bakoreshwa neza kandi neza.