Itandukaniro hagati ya EHEC na HPMC

EHEC na HPMC ni ubwoko bubiri bukoreshwa bwa polymers hamwe nuburyo butandukanye bwimiti nimiterere. EHEC isobanura Ethyl hydroxyethyl selulose, naho HPMC igereranya hydroxypropyl methylcellulose. Muri iki kiganiro, tuzaganira ku itandukaniro riri hagati ya EHEC na HPMC ukurikije imiterere y’imiti, imiterere, imikoreshereze, n’umutekano.

1. Imiterere yimiti

EHEC ni polymer-amazi ashonga ikomoka kuri selile. Nibintu byahinduwe bya selile ether ifite matsinda yombi ya Ethyl na hydroxyethyl ifatanye numugongo wa selile. Urwego rwo gusimbuza (DS) rwa EHEC bivuga umubare wamatsinda ya Ethyl na hydroxyethyl aboneka kuri anhydroglucose (AGU) yumugongo wa selile. DS ya EHEC irashobora kuva kuri 0.2 kugeza kuri 2.5, hamwe nibiciro bya DS byerekana urwego rwo hejuru rwo gusimburwa.

Ku rundi ruhande, HPMC, na polymer iboneka mu mazi ikomoka kuri selile. Ni selile yahinduwe ya selile ifite hydroxypropyl na methyl matsinda yombi yometse kumugongo wa selile. Urwego rwo gusimbuza HPMC bivuga umubare wa hydroxypropyl na methyl matsinda aboneka kuri AGU yumugongo wa selile. DS ya HPMC irashobora kuva kuri 0.1 kugeza 3.0, hamwe nibiciro bya DS byerekana urwego rwo hejuru rwo gusimburwa.

2. Ibyiza

EHEC na HPMC bifite imitungo itandukanye ituma ibera porogaramu zitandukanye. Bimwe mubintu byingenzi bya EHEC na HPMC byerekanwe hano hepfo:

a. Gukemura: EHEC ntishobora gukemuka mumazi kurusha HPMC, kandi gukomera kwayo kugabanuka uko urwego rwo gusimbuza rwiyongera. Ku rundi ruhande, HPMC irashonga cyane mu mazi.

b. Rheologiya: EHEC ni ibikoresho byitwa pseudoplastique, bivuze ko byerekana imyitwarire yoroheje. Ibi bivuze ko ubwiza bwa EHEC bugabanuka uko igipimo cyogosha cyiyongera. Ku rundi ruhande, HPMC, ni ibikoresho bya Newtonian, bivuze ko ububobere bwayo buguma buhoraho hatitawe ku gipimo cyogosha.

c. Imiterere yo gukora firime: EHEC ifite imiterere myiza yo gukora firime, ituma ikoreshwa neza muri coatings na firime. HPMC ifite kandi imiterere yo gukora firime, ariko firime zirashobora kuba zoroshye kandi zikunda gucika.

d. Igihagararo: EHEC irahagaze hejuru yubunini bwa pH nubushyuhe. HPMC nayo irahagaze hejuru ya pH yagutse, ariko ituze ryayo irashobora guterwa nubushyuhe bwo hejuru.

3. Gukoresha

EHEC na HPMC bikoreshwa muburyo butandukanye mubiribwa, imiti, ninganda zita kubantu. Bimwe mubikorwa byingenzi bikoreshwa bya EHEC na HPMC byerekanwe hano hepfo:

a. Inganda zibiribwa: EHEC isanzwe ikoreshwa nkibyimbye, stabilisateur, na emulisiferi mubicuruzwa byibiribwa nka sosi, imyambarire, nibicuruzwa bitetse. HPMC ikoreshwa kandi mubyimbye kandi bigahindura ibicuruzwa byibiribwa, ariko ikoreshwa cyane nkibikoresho byo gutwikira ibicuruzwa bikarishye nka bombo ya gummy na shokora.

b. Inganda zikoreshwa mu bya farumasi: EHEC ikoreshwa nkibikoresho bihuza, bidahwitse, hamwe na tableti yububiko bwa farumasi. HPMC ikoreshwa kandi nka binder, disintegrant, na tablet coating agent mu miti yimiti, ariko ikoreshwa cyane nkumukozi urekura-urekura.

4. Umutekano

EHEC na HPMC mubisanzwe bifatwa nkumutekano mukoresha mubiribwa no gukoresha imiti. Ariko, kimwe nibintu byose bya shimi, hashobora kubaho ingaruka zijyanye no gukoresha.