Ikoreshwa rya CMC mubuvuzi
Carboxymethyl selulose (CMC) ni polymer yamazi yamazi akomoka kuri selile, ikoreshwa cyane mubikorwa byubuvuzi kubera imiterere yihariye, nka biocompatibilité, non-toxicity, hamwe nubushobozi buhebuje bwa mucoadhesive. Muri iki kiganiro, tuzaganira ku buryo butandukanye bwa CMC mu buvuzi.
- Porogaramu y'amaso: CMC ikoreshwa cyane mugutegura amaso, nk'ibitonyanga by'amaso n'amavuta, bitewe n'ubushobozi bwayo bwo kongera igihe cyo gutura ibiyobyabwenge hejuru ya ocular, bityo bigatuma bioavailable iboneka. CMC ikora kandi nk'umubyimba kandi itanga amavuta, igabanya uburakari buterwa no gukoresha ibiyobyabwenge.
- Gukiza ibikomere: hydrogels ishingiye kuri CMC yateguwe kugirango ikoreshe ibikomere. Izi hydrogels zifite amazi menshi kandi zitanga ibidukikije bitose bitera gukira ibikomere. Hydrogels ya CMC nayo ifite biocompatibilité nziza kandi irashobora gukoreshwa nkibiti byo gukura kwingirabuzimafatizo.
- Gutanga ibiyobyabwenge: CMC ikoreshwa cyane muri sisitemu yo gutanga ibiyobyabwenge, nka microsperes, nanoparticles, na liposomes, bitewe na biocompatibilité, biodegradability, hamwe na mucoadhesive. Sisitemu yo gutanga imiti ishingiye kuri CMC irashobora kunoza bioavailable yibiyobyabwenge, kugabanya uburozi bwabyo, kandi bigatanga uburyo bugenewe kubice cyangwa ingingo runaka.
- Porogaramu ya Gastrointestinal: CMC ikoreshwa mugutegura ibinini na capsules kugirango tunonosore imitekerereze yabyo. CMC nayo ikoreshwa nka binder kandi idahwitse mugutegura ibinini bisenya umunwa. CMC ikoreshwa mugutegura guhagarikwa hamwe na emulisiyo kugirango bitezimbere umutekano wabo.
- Gukoresha amenyo: CMC ikoreshwa muburyo bwo kuvura amenyo, nko koza amenyo no koza umunwa, bitewe nubushobozi bwayo bwo gutanga ububobere no kunoza imiterere yimikorere. CMC nayo ikora nka binder, ikumira gutandukanya ibice bitandukanye bigize formulaire.
- Porogaramu ibyara: CMC ikoreshwa muburyo bwo kubyara, nka geles na cream, kubera imiterere ya mucoadhesive. Imiti ishingiye kuri CMC irashobora kunoza igihe cyo gutura ibiyobyabwenge kumitsi ibyara, bityo bikaboneka neza.
Mu gusoza, CMC ni polymer itandukanye hamwe nibikorwa byinshi mubuvuzi. Imiterere yihariye, nka biocompatibilité, idafite uburozi, hamwe nubushobozi bwa mucoadhesive, bituma iba ingirakamaro mu myiteguro y’amaso, gukira ibikomere, uburyo bwo gutanga imiti, gutera gastrointestinal, kuvura amenyo, no gutegura ibyara. Gukoresha imiti ishingiye kuri CMC birashobora guteza imbere bioavailable yibiyobyabwenge, bikagabanya uburozi bwabyo, kandi bigatanga uburyo bwihariye bwo kugaburira ingingo cyangwa ingingo runaka, bityo bikazamura umusaruro w’abarwayi.
Igihe cyo kohereza: Gicurasi-09-2023