Hydroxypropylmethylcellulose (HPMC) ndi polima yosungunuka m'madzi yochokera ku cellulose yachilengedwe ndipo imagwiritsidwa ntchito kwambiri m'mafakitale ambiri chifukwa chotha kupanga ma viscosities osiyanasiyana munjira zamadzi. HPMC ali osiyanasiyana ntchito m'mafakitale mankhwala, chakudya ndi zodzikongoletsera. Viscosity ndi gawo lalikulu la mayankho a HPMC omwe amakhudza momwe amagwirira ntchito pamapulogalamuwa.
Zinthu zomwe zimakhudza mamasukidwe akayendedwe:
1. Kuyikirapo: Kukhazikika kwa HPMC mu yankho kumagwirizana mwachindunji ndi kukhuthala kwa yankho. Pamene ndende ya HPMC ikuwonjezeka, kukhuthala kwa yankho kumawonjezeka pamene maunyolo a polima amakhazikika. Komabe, kuchulukira kwambiri kumatha kubweretsa yankho lolimba komanso ngati gel, lomwe lingakhale losafunikira pamapulogalamu ena.
2. Kulemera kwa maselo: Kulemera kwa maselo a HPMC ndi chinthu chofunika kwambiri chomwe chimakhudza kukhuthala kwa yankho. Pamene kulemera kwa maselo a HPMC kumawonjezeka, kukhuthala kwa yankho kumawonjezekanso chifukwa cha kuwonjezeka kwa unyolo wa polima. HPMC yokhala ndi kulemera kwakukulu kwa maselo imakhala ndi maunyolo ataliatali, zomwe zimapangitsa kuti pakhale njira yowoneka bwino.
3. Kutentha: The viscosity ya HPMC solution imakhudzidwanso ndi kutentha. Pamene kutentha kwa yankho kumawonjezeka, kukhuthala kwa yankho kumachepa. Kuchepa kwa mamasukidwe akayendedwe kumachitika chifukwa cha kuchepa kwa mphamvu zama intermolecular pakati pa maunyolo a polima, zomwe zimapangitsa kuti asamangidwe komanso kuchulukira kwamadzimadzi.
4. pH mtengo: Phindu la pH la yankho lidzakhudzanso kukhuthala kwa yankho la HPMC. Phindu la pH kunja kwa 5.5-8 lingayambitse kuchepa kwa kukhuthala chifukwa cha kusintha kwa kusungunuka ndi mtengo wa polima wa HPMC.
5. Mchere: Mphamvu ya salinity kapena ionic ya yankho imakhudzanso kukhuthala kwa yankho la HPMC. Kuchulukitsa kwa mchere kumasokoneza kuyanjana kwa HPMC polima, zomwe zimapangitsa kuchepa kwa kukhuthala kwa yankho.
6. Kumeta ubweya wa ubweya: Mikhalidwe yometa ubweya yomwe yankho la HPMC likuwonekera lidzakhudzanso kukhuthala kwa yankho. Kumeta ubweya wa zinthu kungayambitse kuchepa kwakanthawi kwa mamasukidwe akayendedwe, monga pakusakaniza kapena kupopera yankho. Akameta ubweya wa ubweya atachotsedwa, viscosity imabwereranso kumalo okhazikika.
Pomaliza:
Kukhuthala kwa njira zamadzimadzi za HPMC kumakhudzidwa ndi zinthu zosiyanasiyana zomwe ziyenera kuganiziridwa popanga mankhwalawo. Kukhazikika, kulemera kwa maselo, kutentha, pH, mchere, ndi kumeta ubweya ndizo zinthu zofunika kwambiri zomwe zimakhudza kukhuthala kwa mayankho a HPMC. Kumvetsetsa izi kungathandize opanga kukhathamiritsa kukhuthala kwa mayankho a HPMC pazogwiritsa ntchito zina. Viscosity ndi mawonekedwe ofunikira a mayankho a HPMC chifukwa amatha kudziwa momwe HPMC imagwirira ntchito komanso kukhazikika kwazinthu zozikidwa pa HPMC.
Nthawi yotumiza: Oct-16-2023