Njira yosungunulira ya Hydroxypropyl methylcellulose (HPMC):

Zinthu za hydroxypropyl methylcellulose (HPMC) zikawonjezedwa mwachindunji m'madzi, zimakhazikika ndikusungunuka, koma kusungunuka kumeneku kumakhala pang'onopang'ono komanso kovuta. Pali njira zitatu zoyankhira pansipa, ndipo ogwiritsa ntchito amatha kusankha njira yabwino kwambiri malinga ndi momwe amagwiritsidwira ntchito:

1. Njira yamadzi otentha: Popeza hydroxypropyl methylcellulose (HPMC) sisungunuka m'madzi otentha, gawo loyambirira la hydroxypropyl methylcellulose (HPMC) limatha kumwazikana m'madzi otentha, ndiyeno litakhazikika, njira zitatu za A zimafotokozedwa ngati. zotsatirazi:

1). Ikani madzi otentha ofunikira mumtsuko ndikutenthetsa pafupifupi 70 ° C. Pang'onopang'ono yonjezerani hydroxypropyl methylcellulose (HPMC) pansi pa kugwedezeka pang'onopang'ono, hydroxypropyl methylcellulose (HPMC) imayamba kuyandama pamwamba pa madzi, ndipo pang'onopang'ono imapanga slurry, kuziziritsa slurry pansi pa kugwedeza.

2). Kutenthetsa madzi 1/3 kapena 2/3 (kuchuluka kofunikira) mumtsuko ndikutenthetsa mpaka 70°C. Malinga ndi njira ya 1), kumwaza hydroxypropyl methylcellulose (HPMC) kukonzekera madzi otentha slurry; Kenaka yikani madzi ozizira otsalawo kapena madzi oundana mumtsuko, kenaka yikani hydroxypropyl methylcellulose (HPMC) slurry yamadzi otentha omwe tatchulawa m'madzi ozizira, ndikuyambitsa, kenaka muziziziritsa kusakaniza.

3). Thirani madzi okwanira 1/3 kapena 2/3 mumtsuko ndikutenthetsa mpaka 70°C. Malinga ndi njira ya 1), kumwaza hydroxypropyl methylcellulose (HPMC) kukonzekera madzi otentha slurry; Kuchuluka kotsala kwa madzi ozizira kapena ayezi kumawonjezeredwa ku slurry yamadzi otentha ndipo kusakaniza kumakhazikika pambuyo poyambitsa.

2. Njira yophatikizira ufa: hydroxypropyl methylcellulose (HPMC) tinthu tating'onoting'ono ta ufa ndi wofanana kapena wokulirapo wa zosakaniza zina za powdery zimamwazikana ndi kusakaniza kowuma, kenako kusungunuka m'madzi, ndiye hydroxypropyl methylcellulose Base cellulose (HPMC) imatha kusungunuka popanda agglomeration. . 3. Organic zosungunulira kunyowetsa njira: pre-kumwazikana kapena yonyowa hydroxypropyl methylcellulose (HPMC) ndi organic solvents monga ethanol, ethylene glycol kapena mafuta, ndiyeno kupasuka m'madzi. Panthawiyi, hydroxypropyl methylcellulose (HPMC) imathanso kusungunuka bwino.