Kodi Hydroxypropyl Methylcellulose (HPMC) imapangidwa bwanji?

Hydroxypropyl methylcellulose (HPMC) ndi polima yosungunuka m'madzi yomwe imagwiritsidwa ntchito kwambiri m'makampani opanga mankhwala, zomangamanga ndi zakudya, pakati pa ena. Amachokera ku cellulose, polima yachilengedwe yomwe imapezeka m'makoma a cellulose. Zotsatirazi ndizofotokozera mwachidule za njira yopangira HPMC:

Gwero la cellulose:

Zopangira zazikulu zopangira HPMC ndi cellulose, yomwe imatha kupangidwa kuchokera kumitengo yamatabwa kapena ma linter a thonje. Mitengo ya nkhuni ndi gwero lofala chifukwa ndi yochuluka komanso yotsika mtengo.

Chithandizo cha alkali:

Cellulose amathandizidwa ndi alkali (kawirikawiri sodium hydroxide) kuchotsa zonyansa ndi hemicellulose. Njira imeneyi, yotchedwa mercerization, imapanga cellulose yoyeretsedwa.

Etherification:

Ma cellulose oyeretsedwa amapangidwa ndi etherification, mankhwala omwe amayambitsa magulu a ether mumsana wa cellulose. Kwa HPMC, magulu onse a hydroxypropyl ndi methyl amalowetsedwa pa molekyulu ya cellulose.

Hydroxypropylation:

Propylene oxide imagwiritsidwa ntchito poyambitsa magulu a hydroxypropyl kukhala cellulose. Gawoli limakhudza momwe propylene oxide ndi cellulose imayendera pamaso pa chothandizira.

Methylation:

Magulu a Methyl amalowetsedwa mu cellulose ya hydroxypropylated pogwiritsa ntchito methyl chloride kapena dimethyl sulfate. Njira imeneyi imatchedwa methylation.

Kusalowerera ndale ndi kutsuka:

Pambuyo anachita etherification, mankhwala ndi neutralized kuchotsa m'munsi otsala. HPMC yotulukayo imatsukidwa kuti ichotse zopangira ndi mankhwala omwe sanagwiritsidwe ntchito.

kuyanika:

Gawo lomaliza limaphatikizapo kuyanika HPMC kuchotsa madzi ochulukirapo ndikupeza chinthu chomwe mukufuna mu ufa kapena mawonekedwe a granular.

Ndikofunika kuzindikira kuti tsatanetsatane wa ndondomeko yopangira akhoza kusiyana pakati pa opanga, ndipo angagwiritse ntchito zinthu zosiyanasiyana, zopangira, ndi ma reagents kuti akwaniritse ntchito yomwe HPMC ikufunira. Kuonjezera apo, njira zoyendetsera khalidwe zimayendetsedwa panthawi yonse yopangira kuti zitsimikizire kusasinthasintha ndi kuyera kwa chinthu chomaliza.