Hydroxypropyl methylcellulose (HPMC) ndi yochokera ku cellulose ndipo imagwiritsidwa ntchito kwambiri m'mafakitale osiyanasiyana chifukwa cha mawonekedwe ake apadera. Ndi nonionic cellulose ether yomwe imapezeka mwa kusintha mamolekyu a cellulose achilengedwe ndi propylene oxide ndi methyl chloride. HPMC nthawi zambiri imagulitsidwa mu mawonekedwe a ufa ndipo imasungunuka m'madzi kuti ikhale yomveka bwino, yopanda mtundu, ya viscous.
Zofunikira za HPMC ndizosiyanasiyana komanso zothandiza pazinthu zambiri. Zina mwazinthu zake zodziwika bwino ndizomwe zimasunga madzi, kukhuthala komanso kupanga mafilimu. HPMC ndi gulu lokhazikika kwambiri lomwe siliwonongeka mosavuta chifukwa cha kutentha kapena kukalamba.
Chimodzi mwazinthu zofunika kwambiri za HPMC ndikutha kusunga mamolekyu amadzi. Makhalidwe ake osunga madzi ndi ofunika kwambiri pa ntchito zosiyanasiyana, makamaka pomanga ndi zomangamanga. Ikawonjezeredwa ku simenti kapena zida zina zomangira, HPMC imatha kuchedwetsa kuyanika, kuletsa kuuma kwambiri komanso kuphulika mwachangu. Posunga mamolekyu amadzi, HPMC imalimbikitsa kuchiritsa koyenera ndi kuthirira madzi, potero kumawonjezera mphamvu ndi kulimba kwa chinthu chomalizidwa.
Chinthu china chofunika kwambiri cha HPMC ndi mphamvu yake yowonjezera. HPMC imakulitsa zakumwa popanga netiweki ya gel ikasungunuka m'madzi. Kunenepa ndikofunikira m'mafakitale ambiri omwe amafunikira kukhuthala kwazinthu zinazake. Mwachitsanzo, m'makampani azakudya, HPMC imagwiritsidwa ntchito ngati chowonjezera mu sosi ndi zovala kuti zisinthe mawonekedwe awo komanso kusasinthika. M'makampani opanga mankhwala, HPMC imagwiritsidwa ntchito ngati chomangira pamapangidwe amapiritsi kuti apititse patsogolo kulumikizana kwawo komanso kupasuka.
HPMC ndiwopanganso bwino kwambiri kupanga mafilimu. Ikasungunuka m'madzi, imatha kupanga filimu yopyapyala, yowonekera, yosinthika. Kuthekera kopanga filimu kwa HPMC kumapangitsa kuti ikhale yofunikira popanga mitundu yolimba yapakamwa ndi zigamba za transdermal. Kapangidwe ka filimu ka HPMC kumathandiza kuti mayamwidwe a mankhwala azikhala bwino popereka chotchinga pakati pa mankhwalawa ndi chilengedwe.
Kuphatikiza pa kusunga madzi, kukhuthala ndi kupanga mafilimu, HPMC ili ndi zinthu zina zofunika. Mwachitsanzo, HPMC amaonetsa zabwino rheological katundu, kutanthauza angagwiritsidwe ntchito kulamulira otaya ndi mamasukidwe akayendedwe amadzimadzi. Kuchuluka kwake kumangiriza kumapangitsa kuti amange particles ndi sediments mu njira zothetsera mavuto, zomwe zimapangitsa kuti zikhale zogwira mtima poyimitsidwa.
HPMC ndi gulu lokhazikika lomwe lili ndi kukana kutentha komanso kukana kukalamba. Sichichita ndi zinthu zina, zomwe zimapangitsa kuti zigwirizane ndi zipangizo zosiyanasiyana. Kukhazikika kwake kumapangitsanso kuti ikhale yoyenera kugwiritsidwa ntchito pazinthu zomwe zimafuna moyo wautali wa alumali.
HPMC ntchito m'mafakitale ambiri, kuphatikizapo zomangamanga, mankhwala, mankhwala chisamaliro munthu, chakudya ndi zodzoladzola. Pomanga, amagwiritsidwa ntchito ngati chosungira madzi mu simenti, konkire ndi matope kuti apititse patsogolo ntchito ndi kuika nthawi. Pazamankhwala, HPMC imagwiritsidwa ntchito ngati binder, disintegrant, and controlled release agent mumapiritsi. Amagwiritsidwanso ntchito ngati viscosity modifier mu ophthalmic solutions.
M'makampani osamalira anthu, HPMC imagwiritsidwa ntchito ngati chowonjezera mu ma shampoos, mafuta odzola ndi zinthu zina zodzikongoletsera kuti ziwongolere mawonekedwe ndi kukhuthala. Amagwiritsidwanso ntchito ngati chopangira filimu mu zodzoladzola kuti athandize kugawa bwino mtundu wa inki komanso kupewa kugwa.
M'makampani azakudya, HPMC imagwiritsidwa ntchito ngati thickener, emulsifier ndi stabilizer muzinthu monga mkaka, soups ndi zakumwa. HPMC imagwiritsidwanso ntchito ngati ❖ kuyanika ndi kupanga mafilimu muzopaka za zipatso, masamba ndi maswiti.
HPMC ndi zosunthika pawiri ndi katundu ambiri zofunika monga kusunga madzi, thickening, ndi mafilimu kupanga katundu. Chifukwa cha katundu wake wosiyanasiyana, amagwiritsidwa ntchito kwambiri m'mafakitale osiyanasiyana, kuphatikizapo zomangamanga, mankhwala, mankhwala osamalira anthu, zakudya ndi zodzoladzola. HPMC ndi gulu lokhazikika lomwe siligwirizana ndi zinthu zina, ndikupangitsa kuti likhale logwirizana ndi zinthu zambiri zosiyanasiyana. Choncho, HPMC ali osiyanasiyana ntchito angathe ndi ziyembekezo yotakata m'mafakitale osiyanasiyana.
Nthawi yotumiza: Sep-13-2023