Kedu ihe kpatara HEMC ji dị mma karịa HPMC?

Hypromellose (HPMC) na hydroxyethylmethylcellulose (HEMC) bụ ihe abụọ a na-ejikarị cellulose eme ihe na ngwa na ụlọ ọrụ ọgwụ, nri na ịchọ mma. Ọ bụ ezie na HPMC na HEMC na-ekerịta ọtụtụ myirịta, ha dị iche n'ụzọ ụfọdụ, na-eme ka otu dị elu karịa nke ọzọ maka ụfọdụ ngwa.

HEMC bụ cellulose ether emezigharịrị enwetara site n'imeghachi methyl cellulose na ethylene oxide na ethyl chloride, wee dochie ethyl maka hydroxyl. Ya mere, HEMC nwere ogo dị elu nke nnọchi (DS) karịa HPMC. DS na-ezo aka na nkezi ọnụọgụ nke ihe nnọchi kwa nkeji glucose, nke na-emetụta njirimara anụ ahụ na kemịkalụ nke polymer. N'ozuzu, DS dị elu na-ebute solubility ka mma na ihe mgbaze organic, ọnụego mgbasa ngwa ngwa, na ụbara mmasị ịbanye mmiri. DS nke HEMC na-abụkarị 1.7-2.0, ebe DS nke HPMC na-adịkarị n'etiti 1.2 na 1.5.

Uru dị iche iche nke HEMC karịa HPMC bụ ikike ijide mmiri dị mma, na-eme ka ọ dị mma maka nhazi nrapado, ihe owuwu na ngwaahịa ndị ọzọ na-achọ ezigbo njide mmiri. HEMC na-eguzogidekwa ọgụ microbial karịa HPMC ma nwee ogologo ndụ. Mmụba hydrophobicity nke HEMC na ọnụnọ nke otu ethyl dị n'azụ ya na-eme ka ọ bụrụ emulsifier magburu onwe ya ma nwee ike imeziwanye nkwụsi ike ogologo oge nke emulsions.

Uru ọzọ nke iji HEMC bụ ndakọrịta ya na ọtụtụ kemịkalụ ndị ọzọ, nke na-enye aka n'ịgbanwe ya na ngwa dị iche iche. Tụkwasị na nke ahụ, HEMC nwere ezigbo ihe nkiri na-emepụta ihe nkiri, nke na-eme ka ọ baa uru maka mmepụta nke mkpuchi na ihe eji eme ihe na mmepụta nke mbadamba nkume, mkpụrụ ọgwụ na granules.

N'aka nke ọzọ, HPMC nwere ezigbo gelling thermal, nke na-eme ka ọ bụrụ nhọrọ magburu onwe ya maka usoro ọgwụ na-ewepụta ngwa ngwa nke chọrọ gels nwere mmetụta okpomọkụ. HPMC nwekwara mma mmiri solubility na ọ dịghị mfe na-akpụ coagglomerates, nke bụ insoluble aggregates nke polymers na ngwọta.

N'ikpeazụ, ma HEMC na HPMC bụ ihe mmepụta cellulose bara uru nke na-enye uru dị iche iche dabere na ngwa ahụ. HEMC nwere njide mmiri ka mma, emulsification, na ndakọrịta na kemịkalụ ndị ọzọ, ebe HPMC nwere ezigbo ọkụ ọkụ yana solubility mmiri. Ya mere, nhọrọ n'etiti HEMC na HPMC dabere na ngwa a chọrọ, usoro mmepụta na ngwaahịa ikpeazụ chọrọ.