HPMC (hydroxypropyl methylcellulose) bụ ihe a na-ejikarị eme ihe na-abụghị ionic mmiri-soluble polymer ihe, nke a na-ejikarị na ọgwụ, nri, ihe owuwu, nlekọta onwe onye na ubi ndị ọzọ.
1. Njirimara ihe owuwu
The molekụla Ọdịdị nke HPMC nwere elu viscosity na ezi rheological Njirimara. Enwere otutu hydroxyl otu (-OH) na agbụ molekụla ya, nke nwere ike ịmepụta njikọ hydrogen na ụmụ irighiri mmiri, ka HPMC wee gbazee nke ọma na mmiri iji mepụta ngwọta colloidal viscosity dị elu. Ngwongwo a na-enye HPMC ohere itolite nke oma n'ime usoro ma bulie viscosity nke ngwaahịa.
2. Mmetụta mmetụta
The ndim mmetụta nke HPMC na-tumadi enweta site mmekọrịta nke molekụla chains ya. Mgbe HPMC gbazere n'ime mmiri, agbụ ndị molekụla ga-ejikọta ibe ha iji mepụta usoro netwọkụ, si otú ahụ na-abawanye viscosity nke ngwọta. Mmetụta a na-esiwanye ike na-apụta ìhè na ngwaahịa mmiri (dị ka ihe ọṅụṅụ, condiments) na ngwaahịa mado (dị ka ointments, ngwaahịa nlekọta anụ ahụ), nke nwere ike imeziwanye uto na iji ahụmahụ nke ngwaahịa ahụ.
3. Nkwụsi ike ka mma
Site na ịba ụba viscosity, HPMC nwekwara ike melite nkwụsi ike nke ngwaahịa. N'ọtụtụ nkwusioru na emulsions, ịba ụba viscosity nwere ike igbochi sedimentation na nkewa nkewa nke ihe siri ike, si otú ahụ na-edobe ịdị n'otu na ọdịdị nke ngwaahịa ahụ. Dịka ọmụmaatụ, na mkpuchi na adhesives, ojiji nke HPMC nwere ike melite nkwụsi ike rheological nke ngwaahịa ahụ ma gbochie ihe omume nke sedimentation na stratification.
4. arụmọrụ ntọhapụ na-achịkwa
N'ebe a na-emepụta ọgwụ, a na-ejikarị HPMC eme ihe dị ka akụkụ nke usoro ntọhapụ ọgwụ na-achịkwa. Site n'ịgbanwe nleba anya na ịdị arọ molekụla nke HPMC, enwere ike nweta ntọhapụ ọgwụ na-akwado ma na-achịkwa ya. Njirimara ọzịza nke HPMC n'ime mmiri na-enye ohere ka a chịkwaa ọnụego ọgwụ n'ime ahụ, si otú ahụ na-emeziwanye nrụpụta ọgwụ na ibelata mmetụta.
5. Nnukwu mgbanwe
HPMC ka nwere ike ịnọgide na-enwe ezigbo ihe ọkụkụ na gburugburu nwere ụkpụrụ pH dị iche iche na ike ionic, nke na-eme ka ọ rụọ ọrụ n'ọtụtụ usoro mgbagwoju anya. Ma ọ bụ usoro acidic, alkaline ma ọ bụ na-anọpụ iche, HPMC nwere ike inye viscosity kwụsiri ike ma melite ngwa ngwa nke ngwaahịa ahụ.
6. Obere itinye uche irè
Tụnyere ndị ọzọ thickeners, HPMC nwere ike n'ụzọ dị irè dịkwuo viscosity na ala ịta, ibelata mmepụta ụgwọ. N'otu oge ahụ, ntinye uche dị ala a nwere ike ibelata mmetụta na ihe ndị ọzọ na-emepụta ma nọgide na-enwe mgbanwe na nkwụsi ike nke usoro ahụ.
7. Ihe na-emetụta
The ndim mmetụta nke HPMC na-emetụta ọtụtụ ihe, gụnyere ụdị HPMC (dị ka dị iche iche molekụla arọ, hydroxyl nnọchi), ngwọta okpomọkụ, ion ịta, wdg Na kpọmkwem ngwa, ọ dị mkpa ime ka kwekọrọ ekwekọ mgbanwe dị ka mkpa. nke ngwaahịa iji nweta mmetụta viscosity kacha mma.
8. Ihe atụ ngwa
N'ụlọ ọrụ nri, a na-ejikarị HPMC eme nri ndị na-adịchaghị abụba na ngwaahịa mmiri ara ehi iji nyere aka melite uto na nkwụsi ike. N'ime ụlọ ọrụ na-ewu ụlọ, a na-eji HPMC na ihe ndị dabeere na ciment iji meziwanye adhesion na ịrụ ọrụ. Na ọgwụ ubi, HPMC na ọtụtụ-eji na mbadamba, capsules na dị iche iche onunu ogwu ụdị ka mma ha fluidity na kwụsie ike.
A pụghị ilele ọrụ HPMC n'ịkwalite viscosity ngwaahịa. Ngwongwo anụ ahụ na kemịkal ya pụrụ iche na-eme ka ọ bụrụ ihe siri ike na nkwụsi ike n'ọtụtụ ụlọ ọrụ. Mgbe ị na-ahọrọ ma na-etinye HPMC, ọ dị mkpa iji mee oke ezi uche dị na ya ma jiri dị ka njirimara na mkpa nke ngwaahịa dị iche iche iji nye egwuregwu zuru oke maka uru ya.
Oge nzipu: Ọktoba 21-2024