Usoro mmepụta nke imi mmiri alkaline bụ usoro a na-ahụkarị maka imepụta hydroxypropyl methyl cellulose (HPMC). Usoro a gụnyere mmeghachi omume nke cellulose na sodium hydroxide (NaOH) na mgbe ahụ na propylene oxide (PO) na methyl chloride (MC) n'okpuru ọnọdụ ụfọdụ.
Usoro nmikpu alkaline nwere uru nke imepụta HPMC nwere nnukwu ngbanwe (DS), nke na-ekpebi njirimara ya dị ka solubility, viscosity, na gelation. Usoro a gụnyere usoro ndị a:
- Nkwadebe nke cellulose
A na-enweta cellulose site na isi mmalite ndị dị ka osisi, owu, ma ọ bụ ihe ọkụkụ ndị ọzọ. A na-ebu ụzọ mee ka cellulose dị ọcha wee mesoo ya na NaOH iji mepụta sodium cellulose, nke bụ etiti na-arụ ọrụ na mmepụta nke HPMC.
- Mmeghachi omume nke Sodium Cellulose na Propylene Oxide (PO)
A na-emeghachikwa sodium cellulose na PO n'ihu ihe na-eme ka tetramethylammonium hydroxide (TMAH) ma ọ bụ sodium hydroxide (NaOH) na oke okpomọkụ na nrụgide. Mmeghachi omume na-ebute nguzobe nke hydroxypropyl cellulose (HPC).
- Mmeghachi omume nke HPC na Methyl Chloride (MC)
A na-emeghachi omume HPC na MC na ọnụnọ nke ihe mkpali dị ka sodium hydroxide (NaOH) ma ọ bụ hydrochloric acid (HCl). Mmeghachi omume na-ebute nguzobe nke hydroxypropyl methyl cellulose (HPMC).
- Ịsacha na ihicha
Mgbe mmeghachi omume ahụ gasịrị, a na-asacha ngwaahịa ahụ na mmiri wee kpoo ya iji nweta HPMC. A na-asachapụ ngwaahịa a site na iji usoro nzacha na centrifugation iji wepụ adịghị ọcha ọ bụla.
Usoro nmikpu alkaline nwere ọtụtụ uru karịa ụzọ ndị ọzọ, gụnyere DS dị elu na ịdị ọcha, ọnụ ala dị ala, yana mfe scalability. A pụkwara iji usoro ahụ mepụta HPMC nwere ihe dị iche iche site n'ịgbanwe ọnọdụ mmeghachi omume dị ka okpomọkụ, nrụgide, na itinye uche.
Otú ọ dị, usoro ahụ nwekwara ụfọdụ drawbacks. Ojiji nke NaOH na MC nwere ike ibute nchekwa na ihe ize ndụ gburugburu ebe obibi, na usoro mmepụta nwere ike na-ewe oge ma chọọ nnukwu ume.
N'ikpeazụ, usoro mmepụta nke mmiri mmiri alkaline bụ usoro a na-ejikarị eme ihe maka ịmepụta HPMC. Usoro na-agụnye mmeghachi omume nke cellulose na NaOH, PO, na MC n'okpuru ọnọdụ ụfọdụ, na-esote ịdị ọcha na ihicha. Ọ bụ ezie na usoro ahụ nwere ụfọdụ ihe ndọghachi azụ, uru ya na-eme ka ọ bụrụ nhọrọ na-ewu ewu maka ụlọ ọrụ mmepụta ihe na ngwa ọgwụ.
Oge nzipu: Eprel-23-2023