Hydroxypropyl methylcellulose na-eji na mbadamba

Hydroxypropyl methylcellulose (HPMC) bụ ihe mgbakwunye a na-ejikarị eme ihe na ọgwụ, gụnyere mbadamba. HPMC bụ polymer nke dabeere na cellulose nke na-agbaze na mmiri ma nwee ihe dị iche iche na-eme ka ọ baa uru na nhazi mbadamba. Edemede a ga-atụle njirimara HPMC na ojiji dị iche iche n'ichepụta mbadamba ihe.

Njirimara nke HPMC:

HPMC bụ polymer hydrophilic nke enwere ike iji dị ka ihe nkedo, thickener, stabilizer, na emulsifier. Ọ nwere nnukwu ihe dị arọ na ihe ngbanwe dị elu (DS), nke na-emetụta solubility na viscosity ya. Enwere ike igbari HPMC na mmiri ma ọ bụ mmanya, mana ọ naghị agbaze n'ọtụtụ ihe mgbaze organic. Ọ bụkwa ihe na-adịghị egbu egbu, enweghị mgbakasị ahụ, na nke na-adịghị ahụkebe, na-eme ka ọ bụrụ nhọrọ dị mma maka ngwa ọgwụ.

Ojiji nke HPMC na mbadamba:

1. Ihe nkedo:

A na-ejikarị HPMC eme ihe dị ka ihe nkedo n'ụdị mbadamba. A na-agbakwunye ya na granules mbadamba iji jide ha ọnụ ma gbochie ha ịdaba. Enwere ike iji HPMC naanị ya ma ọ bụ yana njikọta ya na ihe ndị ọzọ, dị ka microcrystalline cellulose (MCC), iji melite ike ike na ịdị nro.

2. Nkewa:

A pụkwara iji HPMC mee ihe dị ka ihe na-agbasasị n'ụdị mbadamba nkume. A na-agbakwunye ihe ndị na-agbasasị na mbadamba nkume iji nyere ha aka ikewa ma gbazee ngwa ngwa n'ime eriri afọ. HPMC na-arụ ọrụ dị ka ihe mgbasa site na ọzịza na mmiri na ịmepụta ọwa maka mmiri ịbanye na mbadamba nkume. Nke a na-enyere aka ikewapụ mbadamba nkume ma hapụ ihe na-arụ ọrụ.

3. Ntọhapụ a na-achịkwa:

A na-eji HPMC n'ụdị mbadamba ihe eji achị achị iji hazie ntọhapụ nke ihe na-arụ ọrụ. HPMC na-etolite akwa gel gburugburu mbadamba nkume, nke na-achịkwa mwepụta nke ihe na-arụ ọrụ. Enwere ike ịchịkwa ọkpụrụkpụ nke oyi akwa gel site n'ịgbanwe DS nke HPMC, nke na-emetụta viscosity na solubility nke polymer.

4. Ihe mkpuchi ihe nkiri:

A na-ejikwa HPMC dị ka ihe mkpuchi ihe nkiri n'ụdị mbadamba nkume. Ihe mkpuchi ihe nkiri bụ usoro itinye obere oyi akwa polymer n'elu mbadamba nkume iji meziwanye ọdịdị ya, chebe ya pụọ ​​​​na mmiri mmiri, ma kpuchie uto ya. Enwere ike iji HPMC naanị ma ọ bụ jikọtara ya na ihe ndị ọzọ na-ekpuchi ihe nkiri, dị ka polyethylene glycol (PEG), iji meziwanye ihe na-emepụta ihe nkiri nke mkpuchi.

5. Onye nnọchi anya nkwusioru:

A na-ejikwa HPMC dị ka ihe nkwusioru n'ụdị mmiri mmiri. Enwere ike iji ya kwụsịtụ irighiri ihe ndị na-adịghị soluble n'ime mmiri mmiri iji mepụta nkwusioru kwụsiri ike. HPMC na-arụ ọrụ site n'ịkpụ oyi akwa na gburugburu ụmụ irighiri ihe ndị ahụ, na-egbochi ha ka ha na-emewanyewanye ma na-edozi na ala nke akpa ahụ.

Mmechi:

Hydroxypropyl methylcellulose bụ polymer vasatail nke nwere ọtụtụ ojiji n'ụdị mbadamba. Enwere ike iji ya dị ka ihe nkedo, ihe na-agbasa, onye na-ewepụta ihe na-achịkwa, ihe mkpuchi ihe nkiri, na onye nkwusioru. Ngwongwo ya na-adịghị egbu egbu, nke na-adịghị mma, na nke na-adịghị ahụkebe na-eme ka ọ bụrụ nhọrọ dị mma maka ngwa ọgwụ. Enwere ike ịhazi akụrụngwa nke HPMC site n'ịgbanwe ogo ngbanwe, na-eme ka ọ bụrụ polymer na-agbanwe agbanwe nke enwere ike iji mee ihe n'ụdị mbadamba mbadamba.