Ngwa nke mkpuchi Ethylcellulose na Hydrophilic Matrices

Ethylcellulose (EC) bụ polymer a na-ejikarị eme ihe na ụlọ ọrụ ọgwụ maka mkpuchi ọgwụ. Ọ bụ polymer hydrophobic nke nwere ike inye ihe mgbochi iji chebe ọgwụ ahụ site na mmiri mmiri, ìhè, na ihe ndị ọzọ gburugburu ebe obibi. Ihe mkpuchi EC nwekwara ike gbanwee ntọhapụ nke ọgwụ ahụ site na nhazi ahụ, dị ka site n'inye profaịlụ ntọhapụ na-adịgide adịgide.

Hydrophilic matrices bụ ụdị nhazi ọgwụ nke nwere polymers na-agbaze mmiri ma ọ bụ na-aza mmiri, dị ka hydroxypropyl methylcellulose (HPMC). Enwere ike iji matrices ndị a wepụta ntọhapụ nke ọgwụ a na-achịkwa, mana ha nwere ike bụrụ ndị nwere ike ịnweta mmiri na mwepụta ọgwụ na-esote. Iji merie njedebe a, enwere ike itinye mkpuchi EC n'elu matrix hydrophilic iji mepụta oyi akwa nchebe.

Ngwa nke mkpuchi EC na matrices hydrophilic nwere ike inye ọtụtụ uru. Nke mbụ, mkpuchi EC nwere ike ime dị ka ihe mgbochi mmiri iji chebe matriks hydrophilic site na iwepụta mmiri na ntọhapụ ọgwụ na-esote. Nke abụọ, mkpuchi EC nwere ike gbanwee ntọhapụ nke ọgwụ ahụ site na matrix hydrophilic, dị ka site n'inye profaịlụ ntọhapụ na-adịgide adịgide. N'ikpeazụ, mkpuchi EC nwere ike imeziwanye nkwụsi ike anụ ahụ nke nhazi ahụ, dị ka site na igbochi agglomeration ma ọ bụ ịrapagidesi ike nke ihe ndị ahụ.

Enwere ike nweta ntinye nke mkpuchi EC na matrices hydrophilic site na iji usoro mkpuchi dị iche iche, dị ka mkpuchi ịgba, mkpuchi akwa mmiri, ma ọ bụ mkpuchi pan. Nhọrọ nke usoro mkpuchi na-adabere na ihe ndị dị ka ihe mmepụta ihe, ihe mkpuchi mkpuchi chọrọ, na ọnụ ọgụgụ nke mmepụta.

Na nchịkọta, ntinye nke mkpuchi EC na matrices hydrophilic bụ atụmatụ a na-ahụkarị na ụlọ ọrụ ọgwụ iji gbanwee profaịlụ ntọhapụ ma melite nkwụsi ike nke usoro ọgwụ.