Focus on Cellulose ethers

Ngwa nke CMC na Medicine

Ngwa nke CMC na Medicine

Carboxymethyl cellulose (CMC) bụ polymer soluble mmiri nke sitere na cellulose, nke a na-ejikarị eme ihe na ụlọ ọrụ ahụike n'ihi ihe ndị pụrụ iche ya, dị ka biocompatibility, enweghị nsí, na ikike mucoadhesive magburu onwe ya. N'isiokwu a, anyị ga-atụle ngwa dị iche iche nke CMC na nkà mmụta ọgwụ.

  1. Ngwa ophthalmic: A na-eji CMC eme ihe n'ọtụtụ ebe na nkwadebe ophthalmic, dị ka nsị anya na mmanu, n'ihi ike ya na-abawanye oge obibi nke ọgwụ ahụ n'elu anya anya, si otú ahụ na-eme ka bioavailability ya dịkwuo elu. CMC na-arụkwa ọrụ dị ka ihe na-eme ka ọ dị arọ ma na-enye mmanu mmanu, na-ebelata mgbakasị ahụ nke ntinye ọgwụ ahụ kpatara.
  2. Ọgwụgwọ ọnya: E mepụtala hydrogels nke sitere na CMC maka ngwa ọgwụgwọ ọnya. Hydrogels ndị a nwere oke mmiri dị elu ma na-enye ebe mmiri mmiri na-akwalite ọgwụgwọ ọnya. CMC hydrogels nwekwara ezigbo biocompatibility ma enwere ike iji ya dị ka ihe nhụcha maka uto nke mkpụrụ ndụ na anụ ahụ.
  3. Nnyefe ọgwụ: A na-eji CMC eme ihe n'ọtụtụ ebe na sistemụ nnyefe ọgwụ, dị ka microspheres, nanoparticles, na liposomes, n'ihi ịdị ndụ ya, biodegradability, na akụrụngwa mucoadhesive. Usoro nnyefe ọgwụ dabere na CMC nwere ike melite bioavailability nke ọgwụ, belata nsí ha, ma nye nnyefe ezubere iche na anụ ahụ ma ọ bụ akụkụ ahụ akọwapụtara.
  4. Ngwa nke eriri afọ: A na-eji CMC na-emepụta mbadamba nkume na capsules iji melite mgbasa ha na nkesa ha. A na-ejikwa CMC mee ihe dị ka ihe nkedo na nkwụsịtụ n'imepụta mbadamba nkume ndị na-etisa ọnụ. A na-eji CMC eme ihe n'ụdị nkwusioru na emulsions iji meziwanye nkwụsi ike na viscosity ha.
  5. Ngwa eze: A na-eji CMC eme ihe n'ụdị eze, dị ka ntacha eze na ọnụ ọnụ, n'ihi ikike ya inye viscosity ma melite njirimara eruba nke nhazi ahụ. CMC na-arụkwa ọrụ dị ka ihe nkedo, na-egbochi ikewa nke akụkụ dị iche iche nke nhazi ahụ.
  6. Ngwa ikpu: A na-eji CMC eme ihe n'ụdị ikpu, dị ka gels na creams, n'ihi njirimara mucoadhesive ya. Usoro nke sitere na CMC nwere ike imeziwanye oge obibi nke ọgwụ na mucosa ikpu, si otú a na-emeziwanye bioavailability ya.

N'ikpeazụ, CMC bụ polymer dị iche iche nwere ọtụtụ ngwa na ọgwụ. Ngwongwo ya pụrụ iche, dị ka biocompatibility, adịghị egbu egbu, na ikike nke mucoadhesive, na-eme ka ọ bụrụ ihe bara uru na nkwadebe anya, ọgwụgwọ ọnya, usoro nnyefe ọgwụ, usoro eriri afọ, usoro eze, na nkwadebe nke vaginal. Iji usoro dabere na CMC nwere ike melite bioavailability nke ọgwụ, belata nsí ha, ma nye nnyefe ezubere iche na anụ ahụ ma ọ bụ akụkụ ahụ akọwapụtara, si otú a na-eme ka nsonaazụ ndị ọrịa dịkwuo mma.


Oge nzipu: Mee-09-2023
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