HPMC (Hydroxypropyl Methylcellulose) kayan aiki ne da yawa da ake amfani da su a cikin magunguna, abinci, kayan gini da sauran fannoni. Ana iya raba samfuran HPMC zuwa jerin mahara bisa ga buƙatun aikace-aikacen daban-daban, daga cikinsu waɗanda suka fi kowa shine jerin K da jerin E. Kodayake duka biyun HPMC ne, suna da wasu bambance-bambance a tsarin sinadarai, kaddarorin jiki da filayen aikace-aikace.
1. Bambanci a tsarin sinadarai
Abun cikin methoxy: Babban bambanci tsakanin jerin K da E jerin HPMC shine abun ciki na methoxy. Abubuwan da ke cikin methoxy na E jerin HPMC ya fi girma (gaba ɗaya 28-30%), yayin da abun ciki na methoxy na jerin K yana da ƙarancin ƙarancin (kimanin 19-24%).
Abun ciki na Hydroxypropoxy: Sabanin haka, abun ciki na hydroxypropoxy na jerin K (7-12%) ya fi na jerin E (4-7.5%). Wannan bambance-bambancen da ke tattare da sinadarai yana haifar da bambance-bambancen aiki da aikace-aikace tsakanin su biyun.
2. Bambance-bambance a cikin kayan jiki
Solubility: Saboda bambanci a cikin methoxy da hydroxypropoxy abun ciki, da solubility na K jerin HPMC ne dan kadan kasa da na E jerin, musamman a cikin ruwan sanyi. Jerin E ya fi narkewa a cikin ruwan sanyi saboda mafi girman abun ciki na methoxy.
Gel zafin jiki: Gel zafin jiki na K jerin ya fi na E jerin. Wannan yana nufin cewa a ƙarƙashin yanayi guda, yana da wahala ga K jerin HPMC su samar da gel. Gel zafin jiki na jerin E yana da ƙasa, kuma a cikin wasu takamaiman aikace-aikace, kamar kayan gel mai zafi, jerin E na iya yin aiki mafi kyau.
Danko: Ko da yake danko ya dogara ne akan nauyin kwayoyin HPMC, a ƙarƙashin yanayi guda, dankowar E jerin HPMC yawanci ya fi na jerin K. Bambanci a cikin danko yana da tasiri mai mahimmanci akan abubuwan rheological a lokacin shirye-shiryen shirye-shiryen, musamman ma lokacin da aka yi amfani da su zuwa sutura da dakatarwa.
3. Bambance-bambance a cikin filayen aikace-aikacen
Saboda bambance-bambancen tsarin sinadarai da kaddarorin jiki na jerin K da E jerin HPMC, aikace-aikacen su a fannoni daban-daban ma sun bambanta.
Filin magunguna: A cikin shirye-shiryen harhada magunguna, ana yawan amfani da jerin HPMC E a matsayin babban sinadari na shirye-shiryen sakewa. Wannan ya faru ne saboda ƙarancin zafin jiki na gelation da babban danko, wanda ke ba shi damar sarrafa ƙimar sakin miyagun ƙwayoyi lokacin ƙirƙirar fim ɗin ci gaba da sakewa. An fi amfani da jerin K don allunan masu rufin ciki da kuma azaman kayan bangon capsule, saboda yawan zafin jiki na gelation yana hana sakin kwayoyi a cikin ruwan ciki, wanda ke ba da gudummawa ga sakin kwayoyi a cikin hanji.
Filin abinci: A cikin masana'antar abinci, ana yawan amfani da jerin HPMC azaman mai kauri, mai daidaitawa da emulsifier. Saboda babban solubility da danko mai dacewa, zai iya zama mafi tarwatsawa kuma a narkar da shi cikin abinci. Ana amfani da jerin K mafi yawa a cikin abincin da ke buƙatar kiyaye kwanciyar hankali a ƙarƙashin yanayin zafi mai zafi, kamar kayan da aka gasa, saboda yawan zafin jiki na gelation.
Filin kayan gini: A cikin kayan gini, K series HPMC yawanci ana amfani da su a busasshen turmi da kuma busassun foda, suna aiki azaman mai riƙe ruwa da kauri, musamman ga lokutan da ake buƙatar ginawa a yanayin zafi. Jerin E ya fi dacewa da kayan da ke da manyan kaddarorin rheological irin su fenti na bene da sutura saboda ƙananan zafin jiki na gelation da babban danko.
4. Sauran abubuwan da ke tasiri
Baya ga bambance-bambancen da ke sama, takamaiman amfani na daban-daban jerin HPMC na iya shafar abubuwa kamar nauyin kwayoyin halitta, matakin maye gurbin, da rarrabawa. Bugu da ƙari, a cikin aikace-aikace masu amfani, zaɓi na HPMC kuma yana buƙatar la'akari da dacewarsa tare da sauran sinadaran da tasirinsa akan aikin ƙarshen samfurin.
Kodayake jerin K da E na HPMC duka biyun hydroxypropyl methylcellulose ne, suna nuna bambance-bambance a bayyane a cikin kaddarorin jiki da wuraren aikace-aikacen saboda abubuwan da ke ciki daban-daban na ƙungiyoyin methoxy da hydroxypropoxy. Fahimtar waɗannan bambance-bambance yana da mahimmanci don zaɓar nau'in HPMC daidai a aikace-aikace masu amfani.
Lokacin aikawa: Agusta-13-2024