I-HPMC K100m/K15m/K4m Euqual kuya ku-Rutocel&Headcel

IHydroxypropyl Methylcellulose (HPMC) iyipolymer eguquguqukayo esetshenziswa kabanzi ezimbonini ezahlukahlukene ezifana nemithi, ukwakhiwa, ukudla, nezimonyo. Ngaphakathi kombuso weI-HPMC, amabanga ahlukene ayatholakala, okuhlanganisa i-K100m, i-K15m, ne-K4m. Lawa mabanga anezici ezihlukile kanye nezicelo. Lesi sihloko sihlose ukuhlolisisa izakhiwo, izinhlelo zokusebenza, nokulingana kwamabanga e-HPMC K100m, K15m, kanye ne-K4m uma kuqhathaniswa ne-Rutocel kanye ne-Headcel.

Amabanga e-HPMC: K100m, K15m, kanye ne-K4m

I-HPMC K100m:

• I-HPMC K100m iyibanga le-viscosity ephezulu ye-HPMC, ebonakala ngokujiya kwayo kanye nezakhiwo ze-gelling.
• Ivamise ukusetshenziswa ekwenziweni kwemithi njengamathebulethi akhishwe okulawulwayo, lapho kudingeka khona ukukhululwa kwezidakamizwa okuqhubekayo.
• I-viscosity yayo ephezulu inikeza izakhiwo ezinhle kakhulu zokwenza ifilimu, okwenza ifaneleke ukufakwa kwezicelo embonini yezemithi.
• Ukwengeza, i-HPMC K100m ithola izinhlelo zokusebenza embonini yezokwakha njengokujiya ezintweni ezisekelwe kusimende.

I-HPMC K15m:

• I-HPMC K15m iyibanga eliphakathi nendawo le-viscosity le-HPMC, enezinto zokujiya ezimaphakathi kanye ne-gelling.
• Isetshenziswa kakhulu ekwenziweni kwemithi njenge-binder, i-disintegrant, kanye ne-ejenti ekhishwa isikhathi eside.
• Ngenxa ye-viscosity yayo emaphakathi, i-HPMC K15m ilungele ukukhiqiza amafomu emithamo aqinile njengamaphilisi namaphilisi.
• Ngaphezu kwalokho, ithola ukusetshenziswa embonini yokudla njenge-stabilizer kanye ne-ejenti yokuqina emikhiqizweni ehlukahlukene yokudla.

I-HPMC K4m:

• I-HPMC K4m iyibanga eliphansi le-viscosity le-HPMC, elaziwa ngokuqedwa kwayo ngokushesha kanye nezakhiwo ze-hydration.
• Ivamise ukusetshenziswa ekwenziweni kwemithi ukuze kuthuthukiswe ukuqedwa kwezidakamizwa kanye nokuba khona kwe-bioavailability.
• I-HPMC K4m iwusizo ikakhulukazi ekwakhiweni kwethebulethi ehlukanisayo ngomlomo (i-ODT), lapho ukuhlakazeka okusheshayo nokuhlakazeka kubalulekile ekulethweni kwezidakamizwa.
• Ngaphezu kwalokho, isetshenziswa emikhiqizweni yezimonyo efana namakhilimu nama-lotions njenge-thickener kanye ne-emulsifier.

Ukulingana ne-Rutocel ne-Headcel:

I-Rutocel:

• I-Rutocel igama lomkhiqizo elihlotshaniswa nama-cellulose ethers, okuhlanganisa i-HPMC, ekhiqizwa inkampani ethile.
• I-HPMC amabanga K100m, K15m, kanye ne-K4m angabhekwa njengalingana namabanga e-Rutocel ngokusekelwe ku-viscosity nokusebenza kwawo.
• Isibonelo, i-HPMC K100m yabelana ngezakhiwo ezifanayo zokujiya kanye ne-gelling namamaki e-Rutocel afanele izicelo zemithi nezokwakha.
• Ngokufanayo, i-HPMC K15m ihambisana namamaki e-Rutocel asetshenziswa njengama-binders nama-disintegrants ekwakhiweni kwemithi.
• Ngokunjalo, i-HPMC K4m ihambisana namabanga e-Rutocel aziwa ngokuqedwa ngokushesha kanye nezakhiwo ze-hydration.

I-Headcel:

• I-Headcel ingolunye uhlobo olunikeza ama-cellulose ethers, okuhlanganisa i-HPMC, ehlinzeka ngezimboni ezihlukahlukene.
• I-HPMC amamaki e-K100m, i-K15m, ne-K4m angaqhathaniswa nemikhiqizo ye-Headcel ngokusekelwe ekubonakaleni kwayo nokusebenza kwayo.
• I-HPMC K100m ingasebenza njengenye indlela yamamaki e-Headcel ukuze kuqiniswe izinhlelo zokusebenza zokwenza ifilimu.
• I-HPMC K15m ibonisa izakhiwo ezifanayo kumamaki e-Headcel afanele amafomu omthamo oqinile kanye nezicelo zokudla.
• I-HPMC K4m yabelana ngezici namamaki e-Headcel asetshenziselwa ukuqedwa ngokushesha kanye nokuthuthukiswa kokutholakala kwe-bioavailability kwezemithi.

I-HPMC amabanga i-K100m, i-K15m, ne-K4m anikela ngezinhlelo zokusebenza eziningi kuzo zonke izimboni ezihlukahlukene, okuhlanganisa ezemithi, ezokwakha, zokudla, nezimonyo. Lawa mabanga ane-viscosity kanye nokusebenza okuhlukile, okuhambisana nezidingo ezithile zokubunjwa. Ngaphezu kwalokho, zingabhekwa njengezilingana ne-Rutocel kanye nemikhiqizo ye-Headcel ngokusekelwe ezintweni zabo nokusebenza kwazo. Ukuqonda umehluko nokulingana phakathi kwamabanga e-HPMC namanye ama-cellulose ether kusiza abadidiyeli ekukhetheni i-polymer efaneleke kakhulu yezinhlelo zabo zokusebenza.