I-HPMC yokuhlanganisa amafilimu

I-HPMC yeI-Film coatis yindlela yokwenza ifilimu elincanyana le-polymer ngaphezulu kokulungiselela okuqinile. Isibonelo, ungqimba lwezinto ezizinzile ze-polymer lufafazwa ngokufana ebusweni beshidi elisobala ngendlela yokufafaza indlela yokufafaza ama-microns ama-microns amaningana. Ukwakheka kwalolu ngqimba lwefilimu ngaphandle kwethebhulethi ukuthi kunamathebhulethi elilodwa elinamathela kwi-polymer coating impahla ngemuva kokudlula endaweni yokufafaza, bese ithola ingxenye elandelayo yezinto zokufanisa ngemuva kokomiswa. Ngemuva kokunamathela okuphindaphindiwe nokomisa, ukuhlanganiswa kuqediwe kuze kube yilapho wonke ubuso bokulungiselela bumbozwe ngokuphelele. I-Film Coating iyifilimu eqhubekayo, ukushuba kakhulu phakathi kwamagciwane ayi-8 kuye kwayi-100, izinga elithile lokuqina nokuvumelana nezimo, anamathele ngokuqinile ebusweni bomgogodla.

Ngo-1954, u-Abbott wakhiqiza i-batch yokuqala yamashidi wefilimu atholakalayo, kusukela ngaleso sikhathi, ngokuthuthuka okuqhubekayo kanye nokuphelela kwemishini yokukhiqiza nobuchwepheshe, kukhishwe ubuchwepheshe befilimu yamafilimu, ngakho-ke kuthuthukiswe ubuchwepheshe befilimu. Hhayi izinhlobonhlobo kuphela, ubungako kanye nekhwalithi yama-color coating agents akhuphuke ngokushesha, kepha nezinhlobo, amafomu nezimpawu zefilimu ye-coating, imishini yamaphilisi e-TCM athuthukiswe kakhulu. Ngakho-ke, ukusetshenziswa kobuchwepheshe be-film coating sekuyisidingo kanye nentuthuko yezentuthuko yamabhizinisi amakhambi ukuthuthukisa ikhwalithi yomkhiqizo.

Ukusetshenziswa Kwasekuqaleni Kwefilimu Coating ifilimu kwakha izinto zokwakha, kusenenombolo enkulu yemikhiqizo esebenzisa i-HPMChydroxypropyl methylcellulosenjengezinto zokwakha ulwelwesi. KungukuhlanzwaI-HPMCI-Cellulose kusuka ku-COLINTIMI LOKWING NOMA, kanye ne-Sodium Hydroxide Solution ukukhombisa ukuvuvukala kwe-Alkali Cellulose, bese kuthi nge-chloromethane kanye ne-propelene oxide ukwelashwa ukuze uthole i-methylyproseproseproseproselylylylylylylylylylylylylylylylylylylylylylylylylylylylylylylylylylylylylylylysI-HPMC, umkhiqizo ukususa ukungcola ngemuva kokomiswa, ukuchoboza, ukupakishwa. Ngokuvamile, i-viscusic ephansi i-HPMC ephansi isetshenziswa njengeulwembuI-coating impahla, kanye no-2% ~ 10% khambisi asetshenziswa njengesixazululo se-coating. Okubi ukuthi i-viscosity inkulu kakhulu futhi ukwanda kunamandla kakhulu.

Isizukulwane sesibili sefilimu eyakha impahla yi-polyvinyl alcohol (PVA). I-Polyvinyl Alcohol yasungulwa yi-Adfysysis of Polyvinyl Acetate. Amayunithi wokuphinda utshwala weVinyl awakwazi ukusetshenziswa njengabaphenduli ngoba abahlangabezana nobungako kanye nobumsulwa obudingekayo kwi-polymerization. E-methanol, ethanol noma i-ethanol ne-methyl acetha isixazululo esixubile nge-alkali yensimbi noma i-acid ye-inorganic njenge-catalyst, i-hydrolysis ishesha.

I-PVA isetshenziswa kabanzi kwinhlanganisela yefilimu. Ngoba kungukungabonakali emanzini emazingeni okushisa asekamelweni, kuvame ukuhlanganiswa ngokuhlakazeka kwamanzi cishe angama-20. Umphunga wamanzi nomoya-mpilo ukubhekelwa kwe-PVA kuphansi kune-HPMC ne-EC, ngakho-ke amandla okuvinjwa komoya wamanzi nomoya-mpilo kunamandla, okungavikela kangcono umnyombo we-chip.

I-Plistic isho impahla engakhuphula iplastiki yeplastiki ye-Fili yefilimu. Ezinye izinto zokwakha amafilimu zishintsha izakhiwo zazo ezibonakalayo ngemuva kokushiswa kwezinga lokushisa, futhi ukuhamba kwama-macromolekyuli awo kuba kuncane, okwenza ukuqubuka kanzima nokuphulukisa, futhi kube lula ukugqashula. I-Plistic yengezwa ukunciphisa izinga lokushisa le-Glass Transion (TG) futhi yandise ukuguquguquka kwe-coatiny. Amapulasitiki ajwayelekile asetshenziswa ngama-amorphoous polymers anesisindo esikhulu se-molecular kanye nobumbano oluqinile ngezinto zokwakha amafilimu. I-insoluble spitizizizer isiza ukunciphisa ukuvumela ukuhlanganiswa, ngaleyo ndlela yandisa ukuqina kokulungiselela.

Ngokuvamile kuzwakala ukuthi inqubo yepulasitiki yilolo molecule yepulasitiki lifakwe ku-polymer chain, elivimba ukuxhumana phakathi kwama-polymer molecule ngezinga elikhulu. Ukuxhumana kulula lapho ukusebenzisana kwe-polymer-spistizer kunamandla kunokuxhumana kwe-polymer-scicilizer. Ngakho-ke, amathuba ezingxenye ze-polymer ukunyakaza ayanda.

Isizukulwane sesithathu sezinto zokwakha amafilimu yipulasitiki yindlela yamakhemikhali yaxhunyelelwa kufilimu eyakha i-polymer ekwakhelweni

Isibonelo, ifilimu entsha yakha izinto ze-kollicoat® IR eyethulwe yi-BASF ukuthi i-PEG ifakwe ngamakhemikhali ku-PVA polymer ngaphandle kokufaka i-Plistizer, ngakho-ke kungakugwema ukufuduka kwechibi ngemuva kokuhlanganisa