1. Iselula yemvelo
Impahla eyisisekelo eluhlaza yeI-HPMCIngabe i-cellulose yemvelo, evame ukususelwa ku-solip pulp noma u-pulp ukotini. Le micu yezitshalo zemvelo iqukethe inani elikhulu lamayunithi wesakhiwo se-β-glucose futhi ayisisekelo esibalulekile sokukhiqizwa kwe-HPMC. I-cotton cottoose ecwengekile ephithizelayo ivame ukusetshenziswa ekwenziweni kwe-HPMC esezingeni eliphakeme ngenxa yokuqukethwe kwayo okungekho emthethweni.
2. I-Sodium Hydroxide (Naoh)
I-Sodium Hydroxide (Naoh) iyadingeka ekuhlelekeni nasekuthambekeni kwe-cellulose. Imisebenzi yayo eyinhloko ifaka phakathi:
Ukuvuvukala ama-molecule e-cellulose kanye nokwandisa umsebenzi wokuphendula;
Ukubhubhisa indawo ye-crystalline ye-celtulose ukwenza kube lula ukusabela ukusheshisa;
Ukukhuthaza ukusabela okulandelayo kwe-methylution kanye ne-hydroxypropylition.
3. I-Methyl Chloride (CH₃CL)
I-Methyl Chloride (Methyl Cloride) iyindlela ebalulekile ye-methylation reaction ekukhiqizeni kwe-Kimacell®hHPMC. Iphendula nge-alkalised celvule ukuze ithathe amanye amaqembu athile we-hydroxyl (-OH) ngamaqembu we-methoxy (-Och₃) ukuze akhaI-methyl cellulose (MC), ngaleyo ndlela ethuthukisa i-solubity kanye nezakhiwo zomzimba nezamakhemikhali zeselula.
4. I-Phypene Oxide (C₃H₆O)
I-Phylene Oxide isetshenziswa ekuphenduleni kwe-hydroxypropylation, okungethula amaqembu we-hydroxypropyll (-ch₂chohch₃) kumaketanga ama-molecular ama-cellulose. Ukwethulwa kwe-Hydroxypropyl kunga:
Uphinde uthuthukise i-solubility yamanzi ye-HPMC;
Thuthukisa ukubonakala kanye nezinto ezimbongini zembobo yesisombululo sayo;
Thuthukisa ukuqina kwayo emazingeni okushisa ahlukile.
I-5. I-solvent (amanzi noma i-organic solvent)
Amanzi noma i-organic solvent (efana ne-isopropanol, i-methanol, i-njll.) Isetshenziswa njengendlela yokusabela kwinqubo yokukhiqiza ukusiza ukuhlanganiswa komfaniswano kwezinto zokwakha nokuphendula. Ngaphezu kwalokho, amanye ama-solvents asetshenziselwa ukususa imikhiqizo eyenziwe ngezethuliwe kwinqubo elandelayo yokuhlunga kanye nokugeza ukuze aqinisekise ubumsulwa bomkhiqizo.
6. I-Acidic noma i-Alkaline Catalyst
Ukuze uthuthukise izimo zokuphendula futhi uthuthukise ukusebenza kahle kokuthezeka, ama-catalysts acidic noma alkali afana ne-sodium bicarbonate (Nahco₃) noma i-sulfuric acid (h₂so₃)
7. Ezinye izinto zokusetshenziswa ezisizayo
Abanye abaqinisi, ama-inhibitors noma ezinye izengezo zamakhemikhali zingasetshenziswa kwinqubo yokukhiqiza ukuze athuthukise ikhwalithi ye-HPMC, athuthukise ukuqina kwawo, futhi alawule izakhiwo zawo ezenyama nezamakhemikhali.
I-KimaCell®HPMC ikhiqizwa ikakhulukazi nge-alkalization, i-methylation kanye ne-hydroxypropylication ye-cellulose yemvelo.Izinto zalo eziphambili ezilukhuni zifaka:
I-cellulose yemvelo (ikakhulukazi etholakala ku-soni upulpiti noma ukotini ocwengekile)
I-Sodium Hydroxide (Naoh) (ye-Alkalization)
I-methyl chloride (ch₃cl) (ye-methylation)
I-Phypene Oxide (C₃H₆O) (ye-Hydroxypropylation)
Amanzi noma i-organic solvent (ukuphendula nokugeza)
Ama-Catalysts kanye nokuziqinisa (ukwenza ukuphendula okuhle)
I-HPMC isetshenziswa kabanzi kwizimboni eziningi ezifana nomuthi, ukwakhiwa, ukudla kanye nezimbozo ngenxa yokusebenzisa amanzi aso amahle, amandla okulungiswa kwento nokuqina.
Isikhathi sePosi: Feb-11-2025