Umehluko phakathi kwe-methylcellose ne-hydroxypropyll methylcellulose

I-methylcellulose (MC)na-I-Hydroxypropylmethylcellellellellose (HPMC)Zombili izisulu ezivamile ze-cellulose, ezisetshenziswa kabanzi ekudleni, umuthi, izimonyo, ezokwakha kanye nemboni. Yize kwatholakala khona izinhlaka zazo zamakhemikhali eziyisisekelo ezivela ku-cellulose, kukhona umehluko obalulekile kwizakhiwo zamakhemikhali, izakhiwo ezibonakalayo nezindawo zohlelo lokusebenza.

1. Umehluko wamakhemikhali umehluko

I-methylcellulose (MC) yenziwa ngokufaka enye ingxenye yamaqembu e-hydroxyl (-oh) kumaqembu we-cellulose nge-methyl (-Och3). Izinga le-methylation lingalawulwa, livame ukuvezwa njengezinga le-methylation efakwa esikhundleni se-methylation. Ukwakheka kwe-MC kulula kakhulu, ikakhulukazi amaqembu e-hydroxyl kumaketa we-cellulose molecular athathelwa indawo amaqembu we-methylated.

I-Hydroxypropyll methylcellulose (HPMC) isuselwe ku-methylation, futhi iphinde iphinde ibambe ingxenye yamaqembu e-hydroxyl (-oh) kuma-molecule we-cellulose nge-hydroxypropylyl (-c3h'oh) amaqembu. Ngakho-ke, i-HPMC iyinto etholwa yi-methylcellulose, kepha inenkimbinkimbi ngokwengeziwe. I-HPMC iqukethe amaqembu amabili, i-methylypropyl, ngakho-ke isakhiwo sawo siyinkimbinkimbi kakhulu kune-MC.

2. Izakhiwo ezibonakalayo kanye ne-solubity

I-Solubity:

I-methylcellulose ingakha isixazululo se-colloidal emanzini abandayo, kepha akulula ukuncibilikisa emanzini ashisayo. I-solubility yayo ithinteke kakhulu emazingeni okushisa amanzi nenani lamanzi, ikakhulukazi lapho izinga lokushisa likhuphuka, ukuboleka kwe-MC kuzokwehla kakhulu.

I-Hydroxypropylm methylcellulose ine-solubility engcono. Kungakha isixazululo esizinzile emanzini abandayo, futhi i-solubelity yayo ibuye ikhombisa ukuqina okuhle ngaphansi kwezinguquko zamanzi ph kanye lokushisa. I-HPMC inamanzi aphezulu amanzi futhi ingancibilikisa ebangeni lokushisa elibanzi, ikakhulukazi emanzini afudumele.

I-Viscosity:

I-methylcellulose solution ine-viscosity ephansi, ngakho-ke ivame ukusetshenziswa kwezinye izinhlelo zokusebenza ezidinga ukubonakala okuphansi.

I-Hydroxypropyllllylyl methylcellulose isixazululo esiphakeme, okwenza i-HPMC ivame ukusetshenziswa kwezinye izinhlelo zokusebenza ezidinga ukubonwa okuphezulu, okufana nokukhululwa kwezidakamizwa ezintweni zokwakha.

Izakhiwo ze-Gelling:

I-Methylcellose inento ebalulekile ye-genal gelation genomenon, okungukuthi, izokwakha into ekhanyayo ngemuva kokushisa, futhi ichithe futhi lapho amazinga okushisa ehla. Ngakho-ke, kuvame ukusetshenziswa njenge-ejenti ye-gelling ekudleni nasezokwelapha.

I-Hydroxypropyllylylylylyllly ivamisile ukungabi nandaba okushisayo okushisayo, futhi ivame ukwakha isixazululo esizinzile emanzini kunokuba ijeli.

3. Izindawo zohlelo lokusebenza
Imboni yokudla:
I-Methylcellose isetshenziswa ikakhulukazi ekudleni ukuthuthukisa ukunambitheka, inyuse ukubonakala futhi ilondoloze ukwakheka kokudla. Isibonelo, ingasetshenziswa ekudleni okunamakhalori aphansi, u-ayisikhilimu we-ayisikhilimu nemikhiqizo yenyama yemifino. Ngenxa yezakhiwo zayo ze-gelation ezishisayo, ingasetshenziswa futhi njenge-ejenti ye-gelling ekudleni.
I-Hydroxypropyl methylcellulose isetshenziswa kakhulu ekudleni, kepha futhi ingasetshenziswa kokunye kokudla okusebenzayo, okufana nama-moisturizers nama-emulsifers.

Imboni Yezemithi:
I-Methylcellose ivame ukusetshenziswa njenge-excipied for izidakamizwa, ikakhulukazi ezibhebheni, ama-caplule kanye nezingubo zemithi. Ingasetshenziswa futhi njenge-ejenti yokukhishwa okuqhubekayo kwezidakamizwa ze-ophthalmic ukusiza ukwandisa isikhathi sezidakamizwa.
I-Hydroxypropylm methylcellulose isetshenziswa kabanzi kumalungiselelo wezidakamizwa, ikakhulukazi kumathebulethi, amaphilisi kanye namalungiselelo e-liquid. Idlala indima ebalulekile ezinhlelweni zezidakamizwa ezisetshenziselwa ukukhishwa kwezidakamizwa. Ngaphezu kwalokho, i-HPMC nayo isetshenziswa kaningi kuzidakamizwa ze-opthalmic kanye nama-mucosal ukulungisa ama-ejenti.

Imboni Yokwakha:
I-methylcellose isetshenziswa ikakhulukazi njenge-gender kanye ne-ejenti yokugcina amanzi yezinto zokwakha ezifana nesimende naku-gypsum embonini yezokwakha. Kungathuthukisa izakhiwo ezibophayo nokusebenza kwalezi zinto zokwenziwa.
I-Hydroxypropyllylyl methylcellulose isetshenziswa kabanzi ezindaweni zokwakha, ikakhulukazi ekwakheni imikhiqizo efana namathayi anjengodaka lwamathayili kanye nodaka owomile, olunganikeza ukugcinwa kwamanzi okuphezulu.

Imboni yezimonyo:

MCImvamisa isetshenziswa njengomuntu omkhulu, ohlekisayo no-emulsifier kwizimonyo ukuze kuthuthukiswe induduzo yesikhumba nemiphumela yokufudumala.

I-HPMCIvame ukusetshenziswa ekunakekelweni kwesikhumba kanye nemikhiqizo yezinwele, ikakhulukazi emikhiqizweni efana nama-gels, okhilimu kanye nama-shampoos, anganikeza ukwenziwa okungcono nomphumela.

Yize i-methylcellulose (MC) neHydroxypropyll Methylcellulose (HPMC) zombili izinto ze-cellulose, izinhlaka zazo zamakhemikhali kanye nezinto ezibonakalayo zihlukile, ziphumela ezisetshenzisweni ezahlukahlukene emikhakheni ehlukene. I-MC imvamisa ine-viscosity ephansi nezakhiwo ezishisayo ezishisayo, futhi ilungele ukusetshenziswa njenge-ejenti ye-gelling kanye nomkhulu; Ngenkathi i-HPMC ine-solubility engcono futhi ivame ukusetshenziswa kuzinhlelo zokusebenza ezidinga ukubonakala okuphezulu nokuqina okuphezulu, ikakhulukazi ezimbonini zokwakha. Ngokusho kwezidingo ezihlukile zokusebenzisa, ukukhetha okufuywayo okufanele kwe-cellulose kungahlangabezana kangcono nezidingo zohlelo oluthile.