I-Hydroxypropyll methylcellulose (HPMC) umenzi
I-CAS: 9004-65-3
Hydroxypropyl methylcellulose (HPMC) nomaI-Hypromellosekukhona amanzi ancibilikayo methyl celtule ether, esetshenziswa kabanzi ekwakheni, ezenza ngemithi, ukudla, izimonyo, ama-emulsifier, amafilimu, i-ejenti, i-ejenti, i-ejenti, i-ejenti yokuvikela, Futhi kunganikeza ukuguqulwaI-HPMCngokwezidingo zamakhasimende. Ngemuva kokwelashwa okuguquliwe nangokwelashwa komhlaba, singathola izimpahla ezihlakazwa emanzini ngokushesha, zandisa isikhathi esivulekile, anti-sagging, njll.
| Ukubonakala | Okumhlophe noma okumhlophe-okumhlophe okumhlophe |
| Methoxy (%) | 19.0 ~ 24.0 |
| Hydroxypropopoxy (%) | 4.0 ~ 12.0 |
| pH | 5.0 ~ 7.5 |
| Umswakama (%) | ≤ 5.0 |
| Destifure ekulahliseni (%) | ≤ 5.0 |
| Ukushisa kwe-Gelling (℃) | 70 ~ 90 |
| Usayizi wezinhlayiyana | Min.99% udlula ku-100 mesh |
| Ibanga elijwayelekile | I-Viscosity (NDJ, MPA.S, 2%) | I-Viscosity (Brookfield, MPA.S, 2%) |
| I-HPMC MP400 | I-320-480 | I-320-480 |
| I-HPMC MP60M | 48000-72000 | I-24000-36000 |
| I-HPMC MP100M | I-80000-120000 | 40000-55000 |
| I-HPMC MP150m | I-120000-180000 | 55000-65000 |
| I-HPMC MP200M | 160000-240000 | Min70000 |
| I-HPMC MP60MS | 48000-72000 | I-24000-36000 |
| I-HPMC MP100ms | I-80000-120000 | 40000-55000 |
| I-HPMC MP150ms | I-120000-180000 | 55000-65000 |
| I-HPMC MP200ms | 160000-240000 | Min70000 |
Ukusetshenziswa okujwayelekile kwe-HPMC:
Tile anamathela
● Ukugcinwa kwamanzi okuhle: Isikhathi sokuvula isikhathi eside sizokwenza ukunciphisa ukusebenza kahle.
● Ukutholwa okuthuthukile nokuphikiswa okushelelayo: ikakhulukazi amathayili asindayo.
● Ukusebenza okungcono: Ukugcoba kanye ne-plastiki yodaka kuyaqinisekiswa, udaka angasetshenziswa lula futhi asheshe.
Usimende pollarte / danga owomile
● Easy mix formula ngenxa yokubuyiselwa kwamanzi abandayo
● Ukugcinwa kwamanzi okuhle: Ukuvimbela ukulahlekelwa koketshezi kuma-substrate, okuqukethwe okufanele kwamanzi kugcinwa ku-ngxube okuqinisekisa isikhathi esisebusheni.
● Imfuno yokwenyuka kwamanzi: ukukhuphuka kwesikhathi esivulekile, indawo eyandisiwe ye-spry kanye nokwakhiwa okwengeziwe kwezomnotho.
● Ukusakazeka okulula nokuthuthuka okwenziwe ngcono ngenxa yokuvumelana okuthuthukile.
Udonga uPutty
● Ukugcinwa kwamanzi: Okuqukethwe kwamanzi okukhulisiwe ku-slurry.
● I-Anti-sagging: Lapho usakaza ukulungiswa kwejazi elikhulu kungagwenywa.
● Ukwanda kwesivuno sikaDitare: Kuya ngesisindo sengxube elomile kanye nokwakhiwa okufanele, i-HPMC ingakhuphula ivolumu yodaka.
Ukufakwa kwangaphandle kanye nokuqeda uhlelo (ama-EIF)
● Ukutholwa okuthuthukile.
● Amandla amahle we-wetting webhodi le-EPS kanye ne-substrate.
● inciphise ukufakwa komoya kanye nokuthathwa kwamanzi.
Ukuzimela
● Ukuvikelwa ekujuleni kwamanzi nasekudonseni okubonakalayo.
● Awukho umthelela e-slurry fluidy nge-viscosity ephansi
I-HPMC, ngenkathi izici zayo zokugcina amanzi zithuthukisa ukusebenza kokuqeda ebusweni.
Umfutho wokufa
● Ukusebenza okungcono: ubukhulu obufanele nobukhulu.
● Ukugcinwa kwamanzi kuqinisekisa isikhathi eside somsebenzi.
● Ukumelana kwe-SAG: Ikhono elithuthukisiwe le-Gotar Bonding.
Isicelo se-Pharmaceutical Exessient kanye nesicelo sokudla:
| Umsebenzi | Umkhiqizo webanga le-USP / EP / E464 | Isilinganiso somuthi |
| Inqwaba ye-laxative | I-HPMC K4M, HPMC K100M | 3-30% |
| Okhilimu, ama-gels | I-HPMC E4M, HPMC F4M, HPMC K4M | 1-5% |
| Ukulungiselela kwe-Ophthalmic | I-HPMC E50 | 01. - 0.5% |
| Iso lehla amalungiselelo | I-HPMC E4M, HPMC F4M, HPMC K4M | 0.1-0.5% |
| Umenzeli osamile | I-HPMC E3, HPMC E5 | I-1-2% |
| Ama-antacid | I-HPMC E50, HPMC F50 | I-1-2% |
| Amathebhulethi | I-HPMC E5, HPMC E100 | 0.5-5% |
| Umhlangano wamanzi we-Convention | I-HPMC E5, HPMC A4C | 2-6% |
| Imbobo yethebhulethi | I-HPMC E5, HPMC E15 | 0.5-5% |
| I-Matrix elawulwayo yokukhishwa | I-HPMC K100, HPMC K100M | I-20-55% |
Ukupakishwa:
Umkhiqizo we-HPMC ugcwele esikhwameni samaphepha amathathu esikhwameni se-polyethylene esigcwalisiwe, isisindo se-net siyisikhwama ngasinye.
Isitoreji:
Gcina endaweni yokugcina indawo epholile eyomile, kude nomswakama, ilanga, umlilo, imvula.